G:4214

Official Symbol MAP3K1 Aliases MEKK, MEKK1, SRXY6, MEKK 1, MAPKKK1 EntrezGene 4214 UniProt Coming Soon

Unique Molecular Interactions 7 Total Molecular Interactions 9 Total Single Events 75 Unique Interaction Partners 6

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to MAP3K1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to MAP3K1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to MAP3K1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT354704	Binding of MAP3K1 and Pick1	1	0.00	0.76	0.41
2	INT177916	PRKG1 Positive_regulation of Positive_regulation of MAP3K1	1	0.05	1.07	0.14
3	INT215413	ITC1 Negative_regulation of MAP3K1	1	0.04	0.23	0
4	INT348521	TRAF2 Positive_regulation of MAP3K1	1	0.03	0.46	0
5	INT215416	MAP3K1 Regulation of MAPK9	1	0.14	0.64	0
6	INT215412	Binding of MAP3K1 and ITC1	1	0.03	0	0
7	INT215415	MAP3K1 Regulation of MAPK8	1	0.62	0.64	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4214. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4214. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT71788	Gene_expression of MAP3K1	13	0.70	4.9	1.66
2	INT71784	Positive_regulation of Gene_expression of MAP3K1	4	0.34	4.8	0.82
3	INT177933	Positive_regulation of MAP3K1	6	0.42	4.13	0.76
4	INT111602	Negative_regulation of Gene_expression of MAP3K1	1	0.06	0.58	0.58
5	INT102721	Negative_regulation of MAP3K1	2	0.53	8.03	0.3
6	INT177941	Phosphorylation of MAP3K1	2	0.20	1.31	0.24
7	INT173169	Regulation of MAP3K1	2	0.41	1.81	0.09
8	INT215426	Negative_regulation of Negative_regulation of MAP3K1	1	0.39	0.32	0
9	INT333617	Transcription of MAP3K1	1	0.23	0.09	0
10	INT215425	Positive_regulation of Negative_regulation of MAP3K1	1	0.45	0.78	0
11	INT215419	Regulation of Localization of MAP3K1	1	0.41	0.22	0
12	INT215423	Localization of MAP3K1	1	0.68	0.22	0
13	INT333621	Positive_regulation of Transcription of MAP3K1	1	0.16	0.09	0
14	INT215428	Binding of MAP3K1	1	0.44	0.05	0