G:4312

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Official Symbol MMP1
Aliases CLG, CLGN
EntrezGene 4312
UniProt Coming Soon
Unique Molecular Interactions 76
Total Molecular Interactions 105
Total Single Events 641
Unique Interaction Partners 39

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to MMP1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to MMP1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to MMP1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
2 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
3 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24
4 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
5 INT144069 Positive_regulation of TRPV1 Positive_regulation of Gene_expression of MMP1 1 0.43 1.35 1.03
6 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
7 INT121700 IL12RB1 Positive_regulation of Gene_expression of MMP1 1 0.06 0.22 0.9
8 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
9 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
10 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
11 INT260895 CRH Regulation of MMP1 1 0.11 0.31 0.74
12 INT162240 Binding of COL7A1 and MMP1 1 0.03 0.86 0.73
13 INT157935 Negative_regulation of TRPV1 Negative_regulation of Gene_expression of MMP1 1 0.42 0.1 0.68
14 INT157934 TRPV1 Positive_regulation of Positive_regulation of MMP1 1 0.45 0.07 0.57
15 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57
16 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55
17 INT196522 Binding of MMP1 and TIMP1 1 0.39 0.29 0.53
18 INT144070 Gene_expression of TRPV1 Positive_regulation of Positive_regulation of MMP1 1 0.43 0.68 0.52
19 INT144072 Gene_expression of TRPV1 Positive_regulation of MMP1 1 0.43 0.68 0.52
20 INT196527 Positive_regulation of Binding of MMP1 and MMP2 1 0.44 0.74 0.51
21 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51
22 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51
23 INT196520 Binding of MMP1 and MMP2 1 0.33 0.74 0.51
24 INT185800 SPP1 Negative_regulation of Gene_expression of MMP1 1 0.26 1.03 0.49
25 INT277065 CRP Positive_regulation of Gene_expression of MMP1 1 0.41 1.52 0.47
26 INT218706 Olr811 Positive_regulation of MMP1 1 0.00 3.16 0.45
27 INT218707 Mmp1a Negative_regulation of MMP1 1 0.00 2.03 0.38
28 INT264521 PTGDS Negative_regulation of Positive_regulation of MMP1 1 0.06 1.42 0.34
29 INT224462 Positive_regulation of F2RL1 Positive_regulation of MMP1 1 0.10 0.47 0.28
30 INT277066 MMP1 Positive_regulation of Gene_expression of TIMP1 1 0.16 0.76 0.24
31 INT264524 PTGDS Negative_regulation of Gene_expression of MMP1 1 0.09 0.5 0.22
32 INT264516 PTGDS Positive_regulation of TFDP1 Negative_regulation of Gene_expression of MMP1 1 0.02 0.5 0.22
33 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
34 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
35 INT156681 REG3A Negative_regulation of Gene_expression of MMP1 1 0.05 0.39 0.19
36 INT335304 IRF6 Positive_regulation of Gene_expression of MMP1 1 0.01 0.21 0.18
37 INT335302 IRF6 Positive_regulation of MMP1 1 0.01 0.21 0.18
38 INT185815 Binding of MMP1 and SPP1 1 0.21 0.34 0.17
39 INT173599 Binding of MMP1 and Mmp1a 1 0.06 0.5 0.15
40 INT182261 EDN1 Regulation of Gene_expression of MMP1 1 0.17 0.7 0.15
41 INT264385 Binding of IL1B and MMP1 1 0.24 0.09 0.13
42 INT264384 MMP3 Regulation of Positive_regulation of MMP1 1 0.13 0.06 0.12
43 INT264395 MMP9 Regulation of Positive_regulation of MMP1 1 0.13 0.06 0.12
44 INT264411 MMP14 Regulation of Positive_regulation of MMP1 1 0.20 0.06 0.12
45 INT182270 EDN1 Positive_regulation of Gene_expression of MMP1 1 0.18 0.55 0.1
46 INT171263 TNFSF12 Positive_regulation of MMP1 1 0.01 0.57 0.08
47 INT182269 EDN1 Positive_regulation of Localization of MMP1 1 0.17 0.31 0.07
48 INT171261 IL8 Positive_regulation of MMP1 1 0.04 0.05 0.07
49 INT218710 MMP1 Regulation of Positive_regulation of Col1a1 1 0.00 0.15 0.07
50 INT171299 TNFSF12 Negative_regulation of MMP1 1 0.01 0.06 0.07
51 INT355577 ANGPT2 Positive_regulation of MMP1 1 0.04 0.79 0.05
52 INT171281 IL6 Positive_regulation of MMP1 1 0.03 0.38 0.04
53 INT175631 F2RL1 Positive_regulation of Positive_regulation of MMP1 1 0.08 0.69 0.04
54 INT171285 TNFSF12 Negative_regulation of Gene_expression of MMP1 1 0.01 0 0.04
55 INT175629 PAR1 Positive_regulation of Positive_regulation of MMP1 1 0.21 0.69 0.04
56 INT264393 MMP1 Positive_regulation of Gene_expression of MMP13 1 0.29 0.14 0.04
57 INT218708 Mmp1a Regulation of MMP1 1 0.00 0.41 0.03
58 INT171260 TNFSF12 Positive_regulation of Gene_expression of MMP1 1 0.01 0 0.03
59 INT222977 Positive_regulation of COL1A1 Positive_regulation of MMP1 1 0.01 0.61 0.03
60 INT222987 Positive_regulation of COL1A1 Positive_regulation of Protein_catabolism of MMP1 1 0.01 0.61 0.03
61 INT171274 TNF Regulation of Gene_expression of MMP1 1 0.06 0 0.03
62 INT171265 TNF Positive_regulation of Gene_expression of MMP1 1 0.10 0 0.03
63 INT220910 GNS Negative_regulation of MMP1 1 0.01 0 0.03
64 INT218712 Timp1 Regulation of MMP1 1 0.00 0.41 0.03
65 INT106464 STK16 Positive_regulation of Gene_expression of MMP1 2 0.06 0.05 0
66 INT274716 TBL1XR1 Positive_regulation of Gene_expression of MMP1 1 0.02 0.45 0
67 INT335292 IRF6 Positive_regulation of Localization of MMP1 1 0.01 0.06 0
68 INT335310 SLC15A4 Negative_regulation of Gene_expression of MMP1 1 0.00 0.07 0
69 INT264386 Binding of JUN and MMP1 1 0.03 0 0
70 INT185794 SPP1 Regulation of Gene_expression of MMP1 1 0.16 0 0
71 INT335290 SLC15A4 Positive_regulation of Localization of MMP1 1 0.00 0.06 0
72 INT185812 SPP1 Negative_regulation of MMP1 1 0.26 0 0
73 INT335308 SLC15A4 Negative_regulation of MMP1 1 0.00 0.07 0
74 INT264401 Binding of DR1 and MMP1 1 0.05 0 0
75 INT264383 MMP1 Regulation of Binding of MMP13 1 0.28 0 0
76 INT264378 MMP1 Regulation of Transcription of MMP13 1 0.28 0 0
77 INT264404 MMP13 Regulation of Binding of MMP1 1 0.28 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4312. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4312. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72
2 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86
3 INT103210 Localization of MMP1 43 0.78 12.15 15.13
4 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31
5 INT107606 Negative_regulation of MMP1 38 0.42 11.94 10.01
6 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08
7 INT95607 Regulation of MMP1 19 0.60 7.86 6.18
8 INT82871 Protein_catabolism of MMP1 13 0.96 10.71 4.09
9 INT94431 Transcription of MMP1 14 0.56 4.1 3.66
10 INT129961 Regulation of Gene_expression of MMP1 15 0.46 4.88 2.51
11 INT121707 Negative_regulation of Positive_regulation of MMP1 4 0.37 3.1 2.01
12 INT130728 Binding of MMP1 14 0.47 4.7 1.95
13 INT108393 Positive_regulation of Localization of MMP1 5 0.40 0.85 1.91
14 INT106469 Positive_regulation of Transcription of MMP1 5 0.40 1.57 0.81
15 INT224492 Regulation of Regulation of MMP1 1 0.09 0.77 0.66
16 INT150960 Positive_regulation of Positive_regulation of MMP1 4 0.34 0.85 0.44
17 INT196533 Regulation of Positive_regulation of MMP1 3 0.50 1.35 0.43
18 INT220936 Negative_regulation of Transcription of MMP1 2 0.34 0.53 0.29
19 INT122697 Regulation of Localization of MMP1 1 0.35 0.49 0.19
20 INT187825 Positive_regulation of Binding of MMP1 1 0.49 0.59 0.19
21 INT335319 Regulation of Negative_regulation of MMP1 1 0.07 0.18 0.17
22 INT222993 Positive_regulation of Protein_catabolism of MMP1 1 0.10 1.16 0.07
23 INT264445 Negative_regulation of Binding of MMP1 1 0.25 0 0.07
24 INT264433 Positive_regulation of Negative_regulation of MMP1 1 0.29 0.15 0.04
25 INT220942 Negative_regulation of Localization of MMP1 1 0.35 0 0.03
26 INT264432 Regulation of Transcription of MMP1 1 0.16 0.09 0
27 INT220930 Phosphorylation of MMP1 1 0.44 0 0
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