G:4313

From wiki-pain
Jump to: navigation, search
Official Symbol MMP2
Aliases CLG4, MONA, CLG4A, TBE-1, MMP-II
EntrezGene 4313
UniProt Coming Soon
Unique Molecular Interactions 64
Total Molecular Interactions 77
Total Single Events 721
Unique Interaction Partners 37

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to MMP2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to MMP2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to MMP2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT187174 RPS3AP9 Negative_regulation of MMP2 1 0.00 0.9 1.22
2 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
3 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
4 INT190147 MMP12 Positive_regulation of MMP2 Positive_regulation of Protein_catabolism of MMRN1 1 0.03 0.87 0.9
5 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
6 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
7 INT190165 MMP12 Positive_regulation of MMP2 1 0.13 0.72 0.85
8 INT106808 RECK Negative_regulation of MMP2 1 0.40 0.5 0.83
9 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
10 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
11 INT99602 ZNF398 Negative_regulation of MMP2 1 0.14 0.85 0.63
12 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
13 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57
14 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56
15 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55
16 INT150790 ZNF398 Positive_regulation of Localization of MMP2 1 0.04 0.51 0.53
17 INT196521 Binding of MMP2 and TIMP2 1 0.30 0.68 0.52
18 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
19 INT150792 THBS3 Negative_regulation of MMP2 1 0.11 0.49 0.51
20 INT196527 Positive_regulation of Binding of MMP1 and MMP2 1 0.44 0.74 0.51
21 INT196520 Binding of MMP1 and MMP2 1 0.33 0.74 0.51
22 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48
23 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48
24 INT345301 Binding of MMP14 and TIMP2 Positive_regulation of MMP2 1 0.02 0.21 0.48
25 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45
26 INT196348 PTGER2 Negative_regulation of Negative_regulation of MMP2 1 0.01 0.29 0.43
27 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37
28 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37
29 INT99603 ZNF398 Regulation of Transcription of MMP2 1 0.15 0.44 0.33
30 INT99598 ZNF398 Negative_regulation of Gene_expression of MMP2 1 0.10 0.44 0.33
31 INT340615 COL4A4 Regulation of MMP2 1 0.11 0.95 0.32
32 INT99601 ZNF398 Negative_regulation of Transcription of MMP2 1 0.10 0.41 0.3
33 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24
34 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
35 INT225118 Foxm1 Positive_regulation of Gene_expression of MMP2 1 0.01 0.34 0.23
36 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
37 INT205057 MMP3 Negative_regulation of MMP2 1 0.35 3.02 0.2
38 INT304279 ETS1 Positive_regulation of MMP2 1 0.05 1.83 0.17
39 INT185810 Binding of MMP2 and SPP1 1 0.14 0.34 0.17
40 INT304282 ETS1 Positive_regulation of Gene_expression of MMP2 1 0.05 1.83 0.17
41 INT245314 Binding of HYAL1 and MMP2 1 0.16 0.29 0.15
42 INT245312 Negative_regulation of Binding of HYAL1 and MMP2 1 0.19 0.29 0.15
43 INT34484 FPR1 Positive_regulation of Localization of MMP2 1 0.36 0.15 0.15
44 INT195443 MMP2 Positive_regulation of Protein_catabolism of Mmp9 1 0.15 0.95 0.14
45 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14
46 INT290443 Gene_expression of TIMP2 Negative_regulation of MMP2 1 0.06 1.56 0.13
47 INT163404 Negative_regulation of VEGFA Positive_regulation of MMP2 1 0.48 0.07 0.12
48 INT245313 Negative_regulation of Binding of MMP2 and TIMP1 1 0.01 0.45 0.11
49 INT264409 MMP2 Regulation of MMP3 1 0.07 0.06 0.11
50 INT264398 MMP9 Regulation of MMP2 1 0.07 0.06 0.11
51 INT264402 MMP2 Regulation of MMP14 1 0.10 0.06 0.11
52 INT264390 MMP3 Regulation of MMP2 1 0.07 0.06 0.11
53 INT183797 IL17A Positive_regulation of Positive_regulation of MMP2 1 0.03 0.24 0.1
54 INT294457 KLK4 Negative_regulation of MMP2 1 0.01 0 0.1
55 INT205160 Binding of CD44 and MMP2 1 0.09 0.61 0.07
56 INT275463 ZNF69 Negative_regulation of MMP2 1 0.01 0 0.05
57 INT209157 MMP9 Negative_regulation of MMP2 1 0.00 0.16 0.05
58 INT209156 MMP2 Negative_regulation of TIMP1 1 0.00 0.17 0.05
59 INT275464 ZNF69 Negative_regulation of Gene_expression of MMP2 1 0.01 0 0.05
60 INT335303 Binding of IRF6 and MMP2 1 0.01 0 0
61 INT67563 TNF Positive_regulation of Localization of MMP2 1 0.00 0 0
62 INT171757 Binding of MMP2 and SLC7A5 1 0.03 0.29 0
63 INT335301 Binding of MMP2 and SLC15A4 1 0.00 0 0
64 INT67561 TNF Positive_regulation of MMP2 1 0.00 0 0
65 INT335297 IRF6 Positive_regulation of Gene_expression of MMP2 1 0.01 0.07 0
66 INT67562 Negative_regulation of TNF Positive_regulation of MMP2 1 0.00 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4313. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4313. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9
2 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71
3 INT34487 Localization of MMP2 56 0.81 31.41 23.61
4 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72
5 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16
6 INT34485 Negative_regulation of Localization of MMP2 17 0.50 9.96 10.49
7 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42
8 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79
9 INT108628 Regulation of MMP2 27 0.60 14.85 6.06
10 INT90202 Protein_catabolism of MMP2 15 0.94 7.47 5.41
11 INT90374 Positive_regulation of Positive_regulation of MMP2 14 0.50 10.12 5.08
12 INT106468 Regulation of Gene_expression of MMP2 11 0.50 3.53 2.77
13 INT55736 Transcription of MMP2 11 0.68 5.78 2.28
14 INT185829 Negative_regulation of Positive_regulation of MMP2 7 0.40 4.93 2.02
15 INT91396 Positive_regulation of Negative_regulation of MMP2 3 0.33 0.97 1.8
16 INT47889 Binding of MMP2 9 0.41 6.37 1.68
17 INT34486 Regulation of Localization of MMP2 4 0.35 2.19 1.54
18 INT109105 Positive_regulation of Protein_catabolism of MMP2 3 0.46 1.98 1.38
19 INT96581 Negative_regulation of Negative_regulation of MMP2 4 0.57 3.1 1.04
20 INT55738 Positive_regulation of Transcription of MMP2 3 0.65 1.79 0.92
21 INT143953 Regulation of Positive_regulation of MMP2 3 0.44 2.25 0.69
22 INT108629 Negative_regulation of Regulation of MMP2 1 0.41 0.7 0.52
23 INT96580 Negative_regulation of Protein_catabolism of MMP2 2 0.55 0.6 0.51
24 INT166100 Phosphorylation of MMP2 1 0.32 0.56 0.51
25 INT275479 Negative_regulation of Transcription of MMP2 2 0.25 0.43 0.16
26 INT337690 Regulation of Protein_catabolism of MMP2 1 0.02 0.26 0.09
27 INT275481 Negative_regulation of Binding of MMP2 1 0.28 0.07 0.03
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox