G:4780

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Official Symbol NFE2L2
Aliases NRF2
EntrezGene 4780
UniProt Coming Soon
Unique Molecular Interactions 28
Total Molecular Interactions 42
Total Single Events 285
Unique Interaction Partners 17

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to NFE2L2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to NFE2L2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to NFE2L2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT165677 NFE2L2 Negative_regulation of Positive_regulation of HMOX1 1 0.40 0.32 0.44
2 INT165678 NFE2L2 Negative_regulation of HMOX1 1 0.40 0.31 0.43
3 INT209855 NFE2L2 Positive_regulation of Gene_expression of CD36 1 0.27 0.72 0.32
4 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29
5 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28
6 INT101806 Binding of NFE2L2 and KEAP1 Positive_regulation of Gene_expression of GCLC 1 0.55 0.1 0.19
7 INT101808 Binding of NFE2L2 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
8 INT296324 NFE2L2 Regulation of GSTK1 1 0.01 0.91 0.14
9 INT101809 Gene_expression of NFE2L2 Positive_regulation of Gene_expression of GCLC 1 0.75 0 0.12
10 INT101811 NFE2L2 Regulation of Gene_expression of GCLC 1 0.67 0.06 0.12
11 INT199594 FGF7 Positive_regulation of NFE2L2 1 0.01 0.52 0.09
12 INT262755 MRGPRF Positive_regulation of NFE2L2 1 0.18 1.24 0.09
13 INT197553 Binding of NFE2L2 and LILRA3 1 0.03 0.43 0.06
14 INT259638 COPD Positive_regulation of NFE2L2 1 0.03 1.31 0.05
15 INT197546 NFE2L2 Regulation of Gene_expression of ABCC2 1 0.17 0.72 0.04
16 INT197545 KEAP1 Regulation of NFE2L2 3 0.49 0.8 0
17 INT313305 SQSTM1 Regulation of NFE2L2 1 0.35 0.09 0
18 INT177792 Binding of ATF4 and NFE2L2 1 0.06 0.25 0
19 INT311534 Binding of CISH and NFE2L2 1 0.02 0.64 0
20 INT313307 TERT Positive_regulation of NFE2L2 1 0.01 0 0
21 INT246061 KEAP1 Regulation of Positive_regulation of NFE2L2 1 0.34 0 0
22 INT313297 SQSTM1 Positive_regulation of Positive_regulation of NFE2L2 1 0.26 0 0
23 INT246058 Binding of KEAP1 and Positive_regulation of NFE2L2 1 0.38 0 0
24 INT197576 Loh1 Positive_regulation of NFE2L2 1 0.49 1.1 0
25 INT215414 KEAP1 Regulation of Regulation of NFE2L2 1 0.02 0.19 0
26 INT313299 Negative_regulation of Binding of NFE2L2 and KEAP1 1 0.24 0.14 0
27 INT79900 NFE2L2 Positive_regulation of Gene_expression of AQP1 1 0.03 0 0
28 INT313290 Binding of NFE2L2 and Positive_regulation of Binding of NFE2L2 KEAP1 1 0.16 0.38 0
29 INT313292 Positive_regulation of SQSTM1 Regulation of NFE2L2 1 0.26 0.09 0
30 INT262756 STAT3 Positive_regulation of NFE2L2 1 0.31 1.55 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4780. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4780. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101816 Localization of NFE2L2 17 0.77 6.91 1.69
2 INT172479 Positive_regulation of NFE2L2 74 0.70 35.22 0.79
3 INT101818 Gene_expression of NFE2L2 48 0.78 23.8 0.66
4 INT165682 Phosphorylation of NFE2L2 4 0.78 1.53 0.51
5 INT101825 Binding of NFE2L2 9 0.37 3.82 0.48
6 INT177875 Positive_regulation of Positive_regulation of NFE2L2 18 0.66 9.4 0.4
7 INT101829 Positive_regulation of Localization of NFE2L2 9 0.67 3.61 0.38
8 INT101823 Negative_regulation of Gene_expression of NFE2L2 10 0.59 5.15 0.28
9 INT101828 Negative_regulation of Localization of NFE2L2 1 0.41 0 0.19
10 INT101817 Negative_regulation of NFE2L2 13 0.59 6.71 0.17
11 INT197568 Regulation of NFE2L2 17 0.59 7.85 0.15
12 INT101832 Positive_regulation of Gene_expression of NFE2L2 16 0.67 7.41 0.12
13 INT172476 Transcription of NFE2L2 7 0.69 2.47 0.11
14 INT197569 Protein_catabolism of NFE2L2 10 1.00 3.11 0.1
15 INT197571 Positive_regulation of Phosphorylation of NFE2L2 1 0.48 0.44 0.07
16 INT193678 Regulation of Transcription of NFE2L2 1 0.06 0.69 0.04
17 INT197559 Regulation of Positive_regulation of NFE2L2 2 0.45 0.84 0
18 INT172487 Positive_regulation of Transcription of NFE2L2 2 0.50 0.42 0
19 INT246063 Positive_regulation of Negative_regulation of NFE2L2 2 0.47 0.74 0
20 INT197558 Regulation of Gene_expression of NFE2L2 2 0.37 1.05 0
21 INT197557 Positive_regulation of Regulation of NFE2L2 1 0.44 0.56 0
22 INT197564 Positive_regulation of Protein_catabolism of NFE2L2 1 0.66 0.75 0
23 INT246066 Negative_regulation of Positive_regulation of NFE2L2 1 0.59 0.13 0
24 INT246065 Negative_regulation of Protein_catabolism of NFE2L2 1 0.59 1.01 0
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