G:4846

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Official Symbol NOS3
Aliases eNOS, ECNOS
EntrezGene 4846
UniProt Coming Soon
Unique Molecular Interactions 27
Total Molecular Interactions 36
Total Single Events 335
Unique Interaction Partners 24

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to NOS3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to NOS3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to NOS3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
2 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
3 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
4 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
5 INT278226 Binding of FOSB and NOS3 1 0.03 1.22 0.36
6 INT281896 KNG1 Regulation of Binding of KNG1 and NOS3 1 0.02 0.17 0.22
7 INT281901 Binding of KNG1 and NOS3 1 0.05 0.17 0.22
8 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19
9 INT137417 MAPK7 Regulation of Gene_expression of NOS3 1 0.00 0.5 0.19
10 INT269333 Binding of BDKRB2 and NOS3 1 0.02 0 0.17
11 INT269332 Binding of NOS3 and TMPO 1 0.01 0 0.12
12 INT281905 Binding of AGTR2 and NOS3 1 0.08 0.37 0.1
13 INT184814 NOS3 Positive_regulation of Gene_expression of NOS1 1 0.09 0.54 0.1
14 INT281899 Binding of ANG and NOS3 1 0.12 0.37 0.1
15 INT252790 Binding of NOS1 and NOS3 1 0.03 0.37 0.1
16 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 0.01 0.46 0.09
17 INT252803 Binding of NOS3 and ISYNA1 1 0.02 0.32 0.09
18 INT192248 Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
19 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
20 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07
21 INT231438 LEP Positive_regulation of Negative_regulation of NOS3 1 0.09 0.32 0.03
22 INT181618 NOS3 Positive_regulation of INS 1 0.02 0.59 0.03
23 INT281908 VEGFA Positive_regulation of NOS3 1 0.14 0.14 0
24 INT183248 LPA Positive_regulation of NOS3 1 0.02 0 0
25 INT204318 NOS3 Regulation of NOS3 Regulation of SIRT1 1 0.20 0.1 0
26 INT281897 VEGFA Regulation of VEGFA Positive_regulation of NOS3 1 0.04 0.09 0
27 INT133825 TNF Negative_regulation of NOS3 1 0.28 0.06 0
28 INT133824 IL1B Negative_regulation of NOS3 1 0.48 0.06 0
29 INT333560 NOS3 Regulation of HCK 1 0.01 0.2 0
30 INT204321 NOS3 Regulation of SIRT1 1 0.23 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4846. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4846. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
2 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
3 INT70958 Binding of NOS3 19 0.37 11.84 3.29
4 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
5 INT91869 Transcription of NOS3 13 0.67 6.81 2.86
6 INT82166 Regulation of NOS3 14 0.54 7.57 2.08
7 INT91594 Localization of NOS3 12 0.78 5.39 2.02
8 INT107923 Regulation of Gene_expression of NOS3 11 0.61 2.73 1.73
9 INT181639 Positive_regulation of Positive_regulation of NOS3 8 0.41 3.72 1.41
10 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34
11 INT159477 Phosphorylation of NOS3 14 0.72 1.54 1.08
12 INT107922 Positive_regulation of Gene_expression of NOS3 17 0.60 9.32 1.04
13 INT152562 Regulation of Transcription of NOS3 1 0.23 0.34 0.71
14 INT159476 Positive_regulation of Phosphorylation of NOS3 6 0.44 1.43 0.58
15 INT91864 Negative_regulation of Transcription of NOS3 4 0.54 1.41 0.48
16 INT159479 Positive_regulation of Binding of NOS3 2 0.50 0.63 0.41
17 INT269409 Regulation of Phosphorylation of NOS3 1 0.18 0 0.2
18 INT92815 Positive_regulation of Negative_regulation of NOS3 1 0.12 1.03 0.2
19 INT269403 Regulation of Positive_regulation of NOS3 1 0.18 0 0.17
20 INT269395 Regulation of Binding of NOS3 2 0.39 1.84 0.12
21 INT186558 Negative_regulation of Positive_regulation of NOS3 2 0.37 0.26 0.1
22 INT192238 Positive_regulation of Localization of NOS3 2 0.21 0.76 0.09
23 INT336827 Regulation of Regulation of NOS3 1 0.23 0.51 0
24 INT174535 Negative_regulation of Negative_regulation of NOS3 1 0.11 0.32 0
25 INT140156 Positive_regulation of Transcription of NOS3 1 0.31 0 0
26 INT159478 Negative_regulation of Phosphorylation of NOS3 1 0.51 0 0
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