G:4851

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Official Symbol NOTCH1
Aliases hN1, TAN1
EntrezGene 4851
UniProt Coming Soon
Unique Molecular Interactions 15
Total Molecular Interactions 18
Total Single Events 154
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to NOTCH1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to NOTCH1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to NOTCH1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
2 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
3 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
4 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
5 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
6 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
7 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
8 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
9 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
10 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
11 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
12 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
13 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
14 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
15 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4851. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4851. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
2 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
3 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
4 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
5 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
6 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
7 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
8 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
9 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
10 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
11 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
12 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
13 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
14 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
15 INT300174 Negative_regulation of Gene_expression of NOTCH1 1 0.04 0.53 0
16 INT234247 Negative_regulation of Protein_catabolism of NOTCH1 1 0.05 0 0
17 INT130094 Regulation of Positive_regulation of NOTCH1 1 0.45 0.52 0
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