G:4864

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Official Symbol NPC1
Aliases NPC, FLJ98532
EntrezGene 4864
UniProt Coming Soon
Unique Molecular Interactions 13
Total Molecular Interactions 13
Total Single Events 180
Unique Interaction Partners 12

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to NPC1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to NPC1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to NPC1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT18116 NPC1 Negative_regulation of Binding of NPC1 and Oprd1 1 0.13 0 0.54
2 INT18115 Binding of NPC1 and Oprd1 1 0.11 0 0.54
3 INT28006 NPC1 Negative_regulation of Positive_regulation of Rps6ka1 1 0.01 0.37 0.33
4 INT28005 NPC1 Negative_regulation of Rps6ka1 1 0.01 0.45 0.32
5 INT234724 Binding of NPC1 and Cxcl1 1 0.00 0.33 0.21
6 INT86216 Hpd Regulation of NPC1 1 0.02 0.93 0.15
7 INT201543 Binding of NPC1 and RNASE1 1 0.07 1.33 0.08
8 INT201535 Binding of NPC1 and XRCC1 1 0.26 1.6 0.05
9 INT201539 Binding of NPC1 and THY1 1 0.36 1.28 0
10 INT201541 Binding of NPC1 and BRD7 1 0.35 1.59 0
11 INT201537 Binding of NPC1 and HHATL 1 0.16 1.43 0
12 INT201532 RASSF1 Regulation of NPC1 1 0.44 1.41 0
13 INT201540 GADD45G Negative_regulation of NPC1 1 0.32 1.7 0
14 INT201538 Binding of BCL2 and NPC1 1 0.17 1.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4864. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4864. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT76227 Binding of NPC1 30 0.41 32.31 4.05
2 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79
3 INT169862 Regulation of NPC1 13 0.53 13.61 1.84
4 INT18114 Gene_expression of NPC1 45 0.66 57.85 1.44
5 INT106952 Positive_regulation of NPC1 23 0.43 22.9 0.94
6 INT156997 Localization of NPC1 19 0.64 30 0.42
7 INT201565 Positive_regulation of Gene_expression of NPC1 5 0.43 5.94 0.26
8 INT309880 Positive_regulation of Localization of NPC1 1 0.04 1.06 0.25
9 INT222898 Protein_catabolism of NPC1 2 0.76 2.62 0.09
10 INT222902 Negative_regulation of Gene_expression of NPC1 2 0.36 1.6 0.04
11 INT325061 Regulation of Regulation of NPC1 1 0.01 0.76 0.03
12 INT201564 Regulation of Gene_expression of NPC1 2 0.39 3.26 0
13 INT222907 Negative_regulation of Localization of NPC1 1 0.36 1.46 0
14 INT342196 Transcription of NPC1 1 0.17 1.09 0
15 INT222901 Negative_regulation of Phosphorylation of NPC1 1 0.36 0.83 0
16 INT222904 Phosphorylation of NPC1 1 0.69 0.83 0
17 INT222896 Negative_regulation of Binding of NPC1 1 0.37 1.65 0
18 INT222894 Positive_regulation of Binding of NPC1 1 0.43 0.8 0
19 INT222895 Regulation of Binding of NPC1 1 0.39 0.77 0
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