G:4986

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Official Symbol OPRK1
Aliases KOR, OPRK
EntrezGene 4986
UniProt Coming Soon
Unique Molecular Interactions 39
Total Molecular Interactions 57
Total Single Events 414
Unique Interaction Partners 24

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to OPRK1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to OPRK1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to OPRK1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8
2 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 3 0.00 0.63 3.1
3 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
4 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
5 INT133937 Binding of OPRK1 and ARFGEF1 1 0.01 0 1.39
6 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
7 INT67383 Binding of OPRK1 and Pdyn 2 0.00 0 1.25
8 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
9 INT134971 Positive_regulation of OPRK1 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.07
10 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
11 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
12 INT108413 Binding of OPRK1 and Oprd1 1 0.00 0.08 1.04
13 INT51204 Positive_regulation of Binding of OPRK1 and OPRM1 1 0.38 0.3 1.03
14 INT81329 Binding of ARRB1 and OPRK1 1 0.05 0.1 0.93
15 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
16 INT133941 ARFGEF1 Positive_regulation of OPRK1 1 0.02 0 0.76
17 INT133935 DNM2 Positive_regulation of OPRK1 1 0.11 0 0.76
18 INT126598 Binding of BSG and OPRK1 1 0.01 0.05 0.72
19 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
20 INT86264 OPRK1 Negative_regulation of Gene_expression of HIVEP1 1 0.33 1.76 0.51
21 INT81331 ADRBK1 Regulation of OPRK1 1 0.03 0.09 0.48
22 INT112843 Binding of OPRK1 and Nfatc4 1 0.00 0 0.48
23 INT81330 ARRB1 Regulation of OPRK1 1 0.04 0.09 0.47
24 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
25 INT117703 OPRK1 Positive_regulation of Positive_regulation of JUN 1 0.01 0.08 0.47
26 INT81333 Binding of OPRK1 and SNORD50A 1 0.07 0.09 0.46
27 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
28 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
29 INT81335 Negative_regulation of Binding of OPRK1 and SNORD50A 1 0.08 0.1 0.46
30 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
31 INT116929 OPRK1 Positive_regulation of JUN 1 0.28 0.15 0.46
32 INT116931 OPRK1 Regulation of MAPK8 1 0.31 0.07 0.43
33 INT66196 OPRK1 Negative_regulation of Oprd1 1 0.00 0 0.43
34 INT70836 Positive_regulation of OPRK1 Positive_regulation of Binding of CRYGS 1 0.03 0.09 0.36
35 INT51629 Binding of DRD3 and OPRK1 1 0.15 0 0.33
36 INT102953 OPRK1 Positive_regulation of Localization of ADRBK2 1 0.13 0 0.3
37 INT102955 OPRK1 Positive_regulation of Localization of ADRBK1 1 0.13 0 0.3
38 INT102954 Binding of ADRBK1 and OPRK1 1 0.11 0 0.14
39 INT102952 ADRBK2 Positive_regulation of Binding of ADRBK1 and OPRK1 1 0.14 0 0.14
40 INT62775 Regulation of Binding of NT5E and OPRK1 1 0.03 0 0.1
41 INT62776 Binding of NT5E and OPRK1 1 0.02 0 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4986. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4986. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18
2 INT10304 Binding of OPRK1 89 0.48 9.28 49.42
3 INT29105 Positive_regulation of OPRK1 68 0.70 7.06 44.69
4 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49
5 INT20881 Negative_regulation of OPRK1 20 0.43 3.73 13.37
6 INT50191 Positive_regulation of Gene_expression of OPRK1 9 0.67 3.44 7.91
7 INT12699 Transcription of OPRK1 11 0.52 0.08 6.66
8 INT76741 Localization of OPRK1 7 0.68 0.22 5.9
9 INT74182 Positive_regulation of Binding of OPRK1 8 0.49 1.39 5.25
10 INT29354 Regulation of Binding of OPRK1 7 0.60 1.72 5.04
11 INT102363 Negative_regulation of Positive_regulation of OPRK1 7 0.43 0.99 4.25
12 INT66782 Negative_regulation of Gene_expression of OPRK1 4 0.28 1.42 3.41
13 INT80521 Negative_regulation of Binding of OPRK1 4 0.43 0.8 2.93
14 INT52166 Positive_regulation of Positive_regulation of OPRK1 2 0.57 0.48 2.74
15 INT85597 Positive_regulation of Localization of OPRK1 2 0.45 0 2.65
16 INT118924 Positive_regulation of Regulation of OPRK1 2 0.68 0 1
17 INT121687 Positive_regulation of Negative_regulation of OPRK1 1 0.49 0 0.79
18 INT118923 Protein_catabolism of OPRK1 1 0.00 0 0.59
19 INT71672 Phosphorylation of OPRK1 2 0.12 0 0.56
20 INT70840 Regulation of Positive_regulation of OPRK1 1 0.09 0.09 0.5
21 INT146074 Regulation of Transcription of OPRK1 1 0.26 0 0.34
22 INT181237 Negative_regulation of Negative_regulation of OPRK1 1 0.07 0 0.14
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