G:4988

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Official Symbol OPRM1
Aliases MOR, LMOR, MOR1, OPRM, KIAA0403
EntrezGene 4988
UniProt Coming Soon
Unique Molecular Interactions 142
Total Molecular Interactions 205
Total Single Events 1553
Unique Interaction Partners 92

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to OPRM1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to OPRM1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to OPRM1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
2 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
3 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
4 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
5 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
6 INT88730 Binding of OPRM1 and Mop3 1 0.00 0 2.34
7 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
8 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
9 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08
10 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08
11 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
12 INT167319 Binding of OPRM1 and PCSK2 1 0.22 0.63 1.77
13 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
14 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
15 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
16 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64
17 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
18 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
19 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
20 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
21 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
22 INT141676 OPRM1 Positive_regulation of Ltp 1 0.04 0 1.46
23 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 0.04 0 1.46
24 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
25 INT161860 OPRM1 Positive_regulation of OPRM1 Positive_regulation of GRIN1 1 0.56 0.12 1.45
26 INT128915 PENK Regulation of Gene_expression of OPRM1 1 0.22 0.07 1.43
27 INT96796 ITIH4 Regulation of Gene_expression of OPRM1 2 0.20 0.89 1.41
28 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
29 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
30 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
31 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
32 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
33 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
34 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
35 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
36 INT51200 Binding of OPRM1 and PENK 2 0.17 0.23 1.31
37 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
38 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
39 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
40 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
41 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
42 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
43 INT49956 OPRM1 Positive_regulation of SGCG 1 0.53 0.3 1.18
44 INT137144 ITIH4 Regulation of OPRM1 1 0.20 1.13 1.16
45 INT125696 Binding of OPRM1 and SNRNP70 1 0.06 0.99 1.15
46 INT221183 Binding of OPRM1 and Mors1 1 0.00 0 1.12
47 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
48 INT127133 Positive_regulation of OPRM1 Positive_regulation of Protein_catabolism of SUCLG2 1 0.20 0.2 1.1
49 INT90145 Binding of OPRL1 and OPRM1 2 0.27 0.31 1.08
50 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
51 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
52 INT133075 TFAM Positive_regulation of Transcription of OPRM1 1 0.03 0 1.04
53 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
54 INT51204 Positive_regulation of Binding of OPRK1 and OPRM1 1 0.38 0.3 1.03
55 INT1415 Binding of OPRM1 and POMC 3 0.16 0.3 0.98
56 INT51201 Negative_regulation of Binding of OPRM1 and PENK 1 0.20 0.23 0.98
57 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 0.28 0 0.97
58 INT40287 OPRM1 Positive_regulation of Negative_regulation of Prl 1 0.00 0.93 0.96
59 INT133076 STAT6 Positive_regulation of OPRM1 1 0.38 0 0.95
60 INT152388 Binding of NFKB1 and OPRM1 1 0.04 0.14 0.94
61 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
62 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
63 INT152389 Negative_regulation of Binding of NFKB1 and OPRM1 1 0.05 0.14 0.94
64 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
65 INT89314 Binding of CRYGS and OPRM1 1 0.07 0.08 0.91
66 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
67 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
68 INT97012 Binding of CALM1 and OPRM1 1 0.18 0 0.82
69 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82
70 INT89529 OPRM1 Regulation of CALM1 1 0.27 0 0.81
71 INT90143 Negative_regulation of Binding of OPRL1 and OPRM1 1 0.31 0.07 0.8
72 INT151807 Binding of NFATC1 and OPRM1 1 0.19 0 0.79
73 INT133074 CNR2 Positive_regulation of Transcription of OPRM1 1 0.11 0 0.77
74 INT151808 NFATC1 Positive_regulation of Positive_regulation of OPRM1 1 0.20 0 0.76
75 INT96795 ITIH4 Positive_regulation of Gene_expression of OPRM1 1 0.49 0.17 0.76
76 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75
77 INT151810 JUND Positive_regulation of Positive_regulation of OPRM1 1 0.26 0 0.74
78 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
79 INT133070 Positive_regulation of CNR2 Positive_regulation of Transcription of OPRM1 1 0.11 0 0.74
80 INT151806 TRAF3IP2 Positive_regulation of Positive_regulation of OPRM1 1 0.06 0 0.74
81 INT157541 Binding of YY1 and Regulation of Gene_expression of OPRM1 1 0.31 1.21 0.72
82 INT137139 ITIH4 Positive_regulation of OPRM1 1 0.37 0.67 0.72
83 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
84 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
85 INT82759 Binding of IGHG3 and OPRM1 2 0.06 0 0.7
86 INT107741 Binding of OPRM1 and Pld2 1 0.01 0 0.69
87 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
88 INT86638 POMC Negative_regulation of Gene_expression of OPRM1 1 0.34 0.33 0.68
89 INT30503 OPRM1 Regulation of Localization of Prl 1 0.00 0 0.67
90 INT169215 Binding of OPRM1 and CARTPT 1 0.00 0.22 0.67
91 INT169219 Binding of OPRM1 and Coc 1 0.01 0.22 0.67
92 INT137140 HIVEP1 Regulation of Gene_expression of OPRM1 1 0.25 0.69 0.66
93 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
94 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65
95 INT322385 PPBP Negative_regulation of Positive_regulation of OPRM1 1 0.00 0 0.64
96 INT137145 HIVEP1 Regulation of OPRM1 1 0.10 0.7 0.64
97 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
98 INT30502 Negative_regulation of OPRM1 Negative_regulation of Gh 1 0.00 0 0.63
99 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 0.22 0.06 0.61
100 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
101 INT126951 PNOC Positive_regulation of OPRM1 1 0.21 0.06 0.6
102 INT137138 ITIH4 Positive_regulation of Positive_regulation of OPRM1 1 0.42 0.55 0.59
103 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
104 INT159125 Binding of OPRM1 and SUGT1 1 0.03 0.31 0.57
105 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55
106 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
107 INT137143 HIVEP1 Positive_regulation of OPRM1 1 0.15 0.43 0.52
108 INT113241 TRAF3IP2 Regulation of Transcription of OPRM1 1 0.05 0.82 0.52
109 INT113243 TNF Positive_regulation of Transcription of OPRM1 1 0.23 0.84 0.51
110 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51
111 INT144456 Binding of GPM6A and OPRM1 1 0.07 0 0.5
112 INT115800 Positive_regulation of HRASLS Positive_regulation of Positive_regulation of OPRM1 1 0.11 0 0.49
113 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48
114 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48
115 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48
116 INT150534 OPRM1 Positive_regulation of TNF 1 0.03 0.38 0.48
117 INT150535 OPRM1 Positive_regulation of Positive_regulation of TNF 1 0.08 0.38 0.48
118 INT26338 Binding of OPRM1 and Prl 1 0.02 0.37 0.47
119 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47
120 INT46008 OPRM1 Regulation of Localization of PRL 1 0.14 0 0.44
121 INT113537 Binding of OPRM1 and TACR1 1 0.01 0.1 0.42
122 INT80233 Positive_regulation of OPRM1 Positive_regulation of GNAI1 1 0.23 0 0.41
123 INT27451 OPRM1 Positive_regulation of Localization of Lhb 1 0.01 0.1 0.41
124 INT80232 OPRM1 Positive_regulation of GNAI1 1 0.23 0 0.41
125 INT18125 Binding of OPRM1 and Penk 1 0.54 0 0.4
126 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
127 INT55460 Binding of OPRM1 and HERPUD1 1 0.11 0 0.4
128 INT129293 OPRM1 Positive_regulation of Phosphorylation of IKBKE 1 0.05 0.28 0.35
129 INT93201 Positive_regulation of Binding of IGHG3 and OPRM1 1 0.02 0 0.35
130 INT43388 OPRM1 Positive_regulation of Localization of PLOD1 1 0.27 0 0.34
131 INT51630 Binding of ACHE and OPRM1 1 0.11 0 0.33
132 INT98292 IL4 Regulation of Transcription of OPRM1 1 0.05 0 0.33
133 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
134 INT129291 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of RELA 1 0.06 0.27 0.28
135 INT101630 Binding of OPRM1 and SST 1 0.34 0 0.26
136 INT82393 Binding of OPRM1 and MAPRE2 1 0.06 0.1 0.17
137 INT82392 Binding of OPRM1 and VPS11 1 0.25 0.1 0.17
138 INT122358 AR Regulation of Binding of AR and OPRM1 1 0.27 0.14 0.16
139 INT122361 Binding of AR and OPRM1 1 0.26 0.14 0.16
140 INT122362 AR Positive_regulation of Positive_regulation of OPRM1 1 0.32 0.19 0.14
141 INT55459 Binding of OPRM1 and TYR 1 0.08 0 0.1
142 INT150538 OPRM1 Positive_regulation of Negative_regulation of TNF 1 0.08 0 0
143 INT102798 OPRM1 Regulation of INSRR 1 0.01 0 0
144 INT72214 Positive_regulation of PRKCA Regulation of OPRM1 1 0.17 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 4988. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 4988. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36
2 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28
3 INT4658 Binding of OPRM1 188 0.48 25.96 136.24
4 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37
5 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57
6 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27
7 INT1564 Localization of OPRM1 41 0.80 8.03 44.67
8 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75
9 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22
10 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09
11 INT32753 Positive_regulation of Positive_regulation of OPRM1 19 0.62 3.3 16.73
12 INT76863 Negative_regulation of Gene_expression of OPRM1 21 0.57 6.56 13.69
13 INT80883 Positive_regulation of Phosphorylation of OPRM1 13 0.69 1.03 13.65
14 INT33209 Positive_regulation of Binding of OPRM1 8 0.68 0.63 8.95
15 INT31060 Negative_regulation of Binding of OPRM1 12 0.37 2.65 7.75
16 INT101721 Positive_regulation of Transcription of OPRM1 8 0.48 1.22 7.74
17 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36
18 INT42832 Negative_regulation of Positive_regulation of OPRM1 6 0.36 0.96 6.35
19 INT97600 Regulation of Transcription of OPRM1 8 0.52 1.14 6.21
20 INT27118 Regulation of Binding of OPRM1 10 0.62 1.18 5.97
21 INT110545 Regulation of Regulation of OPRM1 7 0.42 1.68 5.67
22 INT32979 Positive_regulation of Localization of OPRM1 5 0.50 0 5.54
23 INT42833 Positive_regulation of Negative_regulation of OPRM1 6 0.48 0.12 4.95
24 INT80882 Negative_regulation of Phosphorylation of OPRM1 4 0.45 0.21 3.68
25 INT13347 Regulation of Negative_regulation of OPRM1 5 0.45 0.64 3.38
26 INT64062 Negative_regulation of Regulation of OPRM1 2 0.41 0.3 2.48
27 INT32980 Positive_regulation of Regulation of OPRM1 2 0.45 0 1.98
28 INT142684 Protein_catabolism of OPRM1 2 0.66 0.48 1.81
29 INT115804 Regulation of Localization of OPRM1 2 0.33 0.12 1.33
30 INT67450 Negative_regulation of Localization of OPRM1 2 0.06 0.24 1.26
31 INT35786 Negative_regulation of Negative_regulation of OPRM1 2 0.33 0.91 1.1
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