G:5027

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Official Symbol P2RX7
Aliases P2X7, MGC20089
EntrezGene 5027
UniProt Coming Soon
Unique Molecular Interactions 10
Total Molecular Interactions 14
Total Single Events 166
Unique Interaction Partners 10

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to P2RX7. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to P2RX7. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to P2RX7. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT281241 Positive_regulation of P2RX7 Negative_regulation of Gene_expression of P2rx3 1 0.03 0.79 0.71
2 INT282821 TACR1 Regulation of P2RX7 1 0.01 2.06 0.54
3 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
4 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
5 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43
6 INT322015 Binding of IL1B and P2RX7 1 0.07 1 0.37
7 INT191128 Positive_regulation of P2RX7 Positive_regulation of Localization of Il1b 1 0.02 0.71 0.34
8 INT217041 TNF Positive_regulation of Gene_expression of P2RX7 1 0.50 0.81 0.34
9 INT322011 BSG Regulation of P2RX7 1 0.00 0.48 0.21
10 INT322037 Binding of P2RX7 and Myh1 1 0.06 0 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5027. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5027. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT127046 Gene_expression of P2RX7 65 0.78 34.28 14.76
2 INT137980 Positive_regulation of P2RX7 30 0.67 22.49 10
3 INT127047 Negative_regulation of P2RX7 10 0.39 7.17 4.01
4 INT191120 Regulation of P2RX7 8 0.41 5.29 2.96
5 INT137978 Localization of P2RX7 6 0.73 5.04 2.84
6 INT137972 Binding of P2RX7 12 0.36 8.01 2.18
7 INT141385 Positive_regulation of Gene_expression of P2RX7 7 0.62 3.95 1.73
8 INT191121 Regulation of Gene_expression of P2RX7 3 0.36 3.69 0.99
9 INT215567 Positive_regulation of Positive_regulation of P2RX7 2 0.45 0.07 0.93
10 INT278119 Positive_regulation of Localization of P2RX7 2 0.45 1.14 0.77
11 INT217017 Transcription of P2RX7 1 0.27 0.36 0.39
12 INT146278 Negative_regulation of Gene_expression of P2RX7 2 0.42 0.21 0.25
13 INT322030 Regulation of Positive_regulation of P2RX7 1 0.41 0.55 0.24
14 INT322025 Positive_regulation of Binding of P2RX7 1 0.45 0 0.1
15 INT351575 Negative_regulation of Positive_regulation of P2RX7 1 0.41 1.81 0.04
16 INT224008 Regulation of Localization of P2RX7 1 0.22 0.74 0.03
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