G:5069

Official Symbol PAPPA Aliases PAPA, DIPLA1, PAPP-A, PAPPA1, ASBABP2, IGFBP-4ase EntrezGene 5069 UniProt Coming Soon

Unique Molecular Interactions 14 Total Molecular Interactions 19 Total Single Events 132 Unique Interaction Partners 12

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PAPPA. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PAPPA. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PAPPA. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT141322	Binding of PAPPA and TNNI3	1	0.09	0.98	0.16
2	INT277012	Binding of PAPPA and ACE2	1	0.02	1.26	0.15
3	INT4107	Binding of CSF2 and PAPPA	1	0.15	0	0.14
4	INT271343	Binding of CRP and PAPPA	1	0.20	0.86	0.1
5	INT271349	ACCS Positive_regulation of PAPPA	1	0.06	0.87	0.09
6	INT277010	Binding of PAPPA and TNNT1	1	0.24	0.99	0.07
7	INT277016	Binding of MB and PAPPA	1	0.10	1	0.07
8	INT106823	Binding of MBP and PAPPA	2	0.17	3.89	0.05
9	INT266070	LIF Regulation of Gene_expression of PAPPA	1	0.35	0.49	0.03
10	INT266067	PAPPA Regulation of Gene_expression of LIF	1	0.35	0.49	0.03
11	INT266081	PAPPA Regulation of Gene_expression of LGALS1	1	0.24	0.49	0.03
12	INT266077	LGALS1 Regulation of Gene_expression of PAPPA	1	0.24	0.49	0.03
13	INT266073	PAPPA Regulation of Gene_expression of PAEP	1	0.27	0.49	0.03
14	INT266080	Binding of PAPPA and MUC16	1	0.40	0.74	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5069. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5069. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT24907	Gene_expression of PAPPA	42	0.75	28.32	6.63
2	INT28145	Binding of PAPPA	26	0.48	7.4	4.96
3	INT117614	Positive_regulation of PAPPA	18	0.67	11.9	3.76
4	INT24904	Negative_regulation of PAPPA	13	0.57	9.93	2.74
5	INT98497	Regulation of PAPPA	5	0.44	3.18	1.74
6	INT107381	Positive_regulation of Gene_expression of PAPPA	4	0.49	2.32	0.85
7	INT24903	Negative_regulation of Gene_expression of PAPPA	6	0.42	2.98	0.52
8	INT158990	Localization of PAPPA	3	0.78	2.48	0.27
9	INT48333	Regulation of Gene_expression of PAPPA	3	0.60	0.95	0.24
10	INT141328	Positive_regulation of Binding of PAPPA	1	0.49	0.94	0.15
11	INT141329	Transcription of PAPPA	1	0.52	0.95	0.15
12	INT271371	Positive_regulation of Positive_regulation of PAPPA	1	0.49	0.76	0.08
13	INT271368	Negative_regulation of Localization of PAPPA	1	0.41	0.65	0.06
14	INT266089	Positive_regulation of Localization of PAPPA	1	0.49	0.44	0.03