G:5069

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Official Symbol PAPPA
Aliases PAPA, DIPLA1, PAPP-A, PAPPA1, ASBABP2, IGFBP-4ase
EntrezGene 5069
UniProt Coming Soon
Unique Molecular Interactions 14
Total Molecular Interactions 19
Total Single Events 132
Unique Interaction Partners 12

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PAPPA. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PAPPA. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PAPPA. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141322 Binding of PAPPA and TNNI3 1 0.09 0.98 0.16
2 INT277012 Binding of PAPPA and ACE2 1 0.02 1.26 0.15
3 INT4107 Binding of CSF2 and PAPPA 1 0.15 0 0.14
4 INT271343 Binding of CRP and PAPPA 1 0.20 0.86 0.1
5 INT271349 ACCS Positive_regulation of PAPPA 1 0.06 0.87 0.09
6 INT277010 Binding of PAPPA and TNNT1 1 0.24 0.99 0.07
7 INT277016 Binding of MB and PAPPA 1 0.10 1 0.07
8 INT106823 Binding of MBP and PAPPA 2 0.17 3.89 0.05
9 INT266070 LIF Regulation of Gene_expression of PAPPA 1 0.35 0.49 0.03
10 INT266067 PAPPA Regulation of Gene_expression of LIF 1 0.35 0.49 0.03
11 INT266081 PAPPA Regulation of Gene_expression of LGALS1 1 0.24 0.49 0.03
12 INT266077 LGALS1 Regulation of Gene_expression of PAPPA 1 0.24 0.49 0.03
13 INT266073 PAPPA Regulation of Gene_expression of PAEP 1 0.27 0.49 0.03
14 INT266080 Binding of PAPPA and MUC16 1 0.40 0.74 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5069. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5069. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24907 Gene_expression of PAPPA 42 0.75 28.32 6.63
2 INT28145 Binding of PAPPA 26 0.48 7.4 4.96
3 INT117614 Positive_regulation of PAPPA 18 0.67 11.9 3.76
4 INT24904 Negative_regulation of PAPPA 13 0.57 9.93 2.74
5 INT98497 Regulation of PAPPA 5 0.44 3.18 1.74
6 INT107381 Positive_regulation of Gene_expression of PAPPA 4 0.49 2.32 0.85
7 INT24903 Negative_regulation of Gene_expression of PAPPA 6 0.42 2.98 0.52
8 INT158990 Localization of PAPPA 3 0.78 2.48 0.27
9 INT48333 Regulation of Gene_expression of PAPPA 3 0.60 0.95 0.24
10 INT141328 Positive_regulation of Binding of PAPPA 1 0.49 0.94 0.15
11 INT141329 Transcription of PAPPA 1 0.52 0.95 0.15
12 INT271371 Positive_regulation of Positive_regulation of PAPPA 1 0.49 0.76 0.08
13 INT271368 Negative_regulation of Localization of PAPPA 1 0.41 0.65 0.06
14 INT266089 Positive_regulation of Localization of PAPPA 1 0.49 0.44 0.03
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