G:5141

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Official Symbol PDE4A
Aliases PDE4, DPDE2, PDE46
EntrezGene 5141
UniProt Coming Soon
Unique Molecular Interactions 12
Total Molecular Interactions 14
Total Single Events 224
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PDE4A. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PDE4A. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PDE4A. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT127663 IRF6 Positive_regulation of PDE4A 1 0.14 0.76 0.48
2 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
3 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
4 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47
5 INT273172 Negative_regulation of PDE4A Negative_regulation of Localization of CD4 1 0.11 0.74 0.37
6 INT226365 Negative_regulation of PDE4A Negative_regulation of Localization of IL5 1 0.05 0.18 0.16
7 INT226382 Negative_regulation of PDE4A Negative_regulation of Localization of IL4 1 0.12 0.18 0.16
8 INT273171 PDE4A Regulation of IL8 1 0.05 0.53 0.15
9 INT263176 Binding of PDE4A and COPD 1 0.01 1 0.15
10 INT273185 PDE4A Regulation of Gene_expression of Mmp12 1 0.08 0.57 0.13
11 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05
12 INT263198 Pde5a Negative_regulation of PDE4A 1 0.09 0.16 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5141. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5141. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59
2 INT79456 Gene_expression of PDE4A 35 0.77 19.42 7.42
3 INT127668 Positive_regulation of PDE4A 12 0.68 8.39 5.13
4 INT98557 Regulation of PDE4A 12 0.44 8.42 2.56
5 INT79455 Positive_regulation of Gene_expression of PDE4A 3 0.67 2.07 1.5
6 INT209138 Negative_regulation of Negative_regulation of PDE4A 4 0.42 3.84 1.21
7 INT139117 Negative_regulation of Gene_expression of PDE4A 4 0.42 2.28 1.02
8 INT127669 Regulation of Negative_regulation of PDE4A 4 0.45 2.74 0.88
9 INT263129 Positive_regulation of Negative_regulation of PDE4A 3 0.35 2.92 0.86
10 INT209136 Regulation of Gene_expression of PDE4A 3 0.27 1.63 0.49
11 INT103316 Localization of PDE4A 2 0.68 1.76 0.41
12 INT209137 Negative_regulation of Positive_regulation of PDE4A 1 0.42 0.8 0.37
13 INT257213 Binding of PDE4A 5 0.36 1.69 0.3
14 INT209140 Transcription of PDE4A 3 0.71 0.59 0.26
15 INT263124 Positive_regulation of Regulation of PDE4A 1 0.26 0.65 0.24
16 INT263128 Negative_regulation of Binding of PDE4A 3 0.22 1.33 0.18
17 INT263130 Phosphorylation of PDE4A 2 0.42 0.67 0.11
18 INT209139 Regulation of Transcription of PDE4A 1 0.61 0.28 0.04
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