G:5154

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Official Symbol PDGFA
Aliases PDGF1, PDGF-A
EntrezGene 5154
UniProt Coming Soon
Unique Molecular Interactions 41
Total Molecular Interactions 54
Total Single Events 213
Unique Interaction Partners 30

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PDGFA. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PDGFA. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PDGFA. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
2 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
3 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
4 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
5 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
6 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18
7 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15
8 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15
9 INT238331 PDGFA Regulation of Gene_expression of GOPC 1 0.04 0 0.14
10 INT238330 Binding of PDGFA and Regulation of Gene_expression of GOPC 1 0.06 0 0.14
11 INT238333 Binding of PDGFA and Regulation of Gene_expression of ADAMTS1 1 0.06 0 0.14
12 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14
13 INT155687 PDGFA Positive_regulation of Phosphorylation of FBRS 1 0.01 0.43 0.14
14 INT238336 PDGFA Regulation of Negative_regulation of ADAMTS5 1 0.04 0 0.14
15 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14
16 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12
17 INT347302 PDGFA Positive_regulation of ITK 1 0.04 1.4 0.09
18 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08
19 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08
20 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
21 INT231440 PDGFA Positive_regulation of Gene_expression of HGF 1 0.16 0.83 0.07
22 INT231434 FN1 Positive_regulation of Gene_expression of PDGFA 1 0.04 0.83 0.07
23 INT246539 EGF Negative_regulation of Gene_expression of PDGFA 1 0.06 0.38 0.07
24 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
25 INT246538 PDGFA Negative_regulation of Gene_expression of EGF 1 0.06 0.38 0.07
26 INT231441 PDGFA Positive_regulation of Gene_expression of VEGFA 1 0.17 0.83 0.07
27 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
28 INT279291 PDGFA Positive_regulation of PDGFRB 1 0.16 1.02 0.06
29 INT279275 PDGFA Positive_regulation of TXK 1 0.05 1.02 0.06
30 INT279276 PDGFA Positive_regulation of NCOR2 1 0.00 1.02 0.06
31 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06
32 INT347304 PDGFA Positive_regulation of Gene_expression of AKT1 1 0.19 0.6 0
33 INT352995 IPMK Regulation of PDGFA 1 0.00 0.66 0
34 INT315868 Vhl Positive_regulation of Transcription of PDGFA 1 0.00 1.39 0
35 INT192328 UBR7 Regulation of Phosphorylation of PDGFA 1 0.00 0 0
36 INT315856 FLT3 Positive_regulation of Gene_expression of PDGFA 1 0.01 1.15 0
37 INT194362 PDGFA Regulation of EGFR 1 0.23 1.56 0
38 INT347296 PDGFA Positive_regulation of CCL16 1 0.06 0.6 0
39 INT286902 Binding of PDGFA and VEGFA 1 0.24 1.1 0
40 INT198002 KDR Negative_regulation of PDGFA 1 0.09 0.94 0
41 INT193307 Binding of PDGFA and PRNP 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5154. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5154. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
2 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
3 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
4 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
5 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
6 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
7 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79
8 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76
9 INT210390 Binding of PDGFA 12 0.36 6.78 0.63
10 INT198048 Protein_catabolism of PDGFA 2 0.28 2.05 0.5
11 INT343801 Negative_regulation of Transcription of PDGFA 1 0.29 0.37 0.5
12 INT192346 Positive_regulation of Localization of PDGFA 5 0.37 1.52 0.29
13 INT155694 Phosphorylation of PDGFA 2 0.58 0.42 0.13
14 INT210396 Negative_regulation of Binding of PDGFA 1 0.02 1.6 0.13
15 INT278037 Positive_regulation of Transcription of PDGFA 4 0.07 2.39 0.12
16 INT286904 Regulation of Binding of PDGFA 1 0.30 0.74 0.04
17 INT292120 Regulation of Regulation of PDGFA 1 0.12 0.93 0
18 INT347305 Negative_regulation of Positive_regulation of PDGFA 1 0.17 0.56 0
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