G:5173

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Official Symbol PDYN
Aliases ADCA, PENKB, SCA23, MGC26418
EntrezGene 5173
UniProt Coming Soon
Unique Molecular Interactions 66
Total Molecular Interactions 106
Total Single Events 1030
Unique Interaction Partners 54

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PDYN. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PDYN. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PDYN. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10268 Binding of PDYN and POMC 11 0.39 0.08 10.36
2 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8
3 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77
4 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 3 0.00 0.63 3.1
5 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14
6 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08
7 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08
8 INT23755 Mptp1 Regulation of PDYN 1 0.01 2.27 1.98
9 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54
10 INT30463 Binding of PDYN and Penk 2 0.01 0 1.5
11 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46
12 INT41591 Binding of PDYN and FAIM3 1 0.00 0 1.41
13 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
14 INT40900 PDYN Regulation of Localization of POMC 2 0.07 0.56 1.22
15 INT240095 Binding of PDYN and Oprk1 1 0.52 1.3 1.22
16 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
17 INT79094 PDYN Positive_regulation of PRL 1 0.35 0.09 1.07
18 INT20888 POMC Positive_regulation of Localization of PDYN 1 0.40 0 0.92
19 INT42765 Binding of PDYN and Oprl1 1 0.00 0 0.87
20 INT29781 PDYN Negative_regulation of Npr1 1 0.00 0.22 0.84
21 INT18663 PDYN Negative_regulation of Binding of Gnrhr 1 0.01 0 0.83
22 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
23 INT133939 Binding of OPRL1 and PDYN 1 0.00 0 0.73
24 INT133934 Binding of OPRD1 and PDYN 1 0.02 0 0.73
25 INT14178 DHCR24 Positive_regulation of Localization of PDYN 1 0.05 0 0.72
26 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72
27 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
28 INT14177 DHCR24 Positive_regulation of PDYN 1 0.05 0 0.71
29 INT45497 PDYN Positive_regulation of TNFRSF10B 1 0.52 0 0.7
30 INT133944 Binding of PDYN and TP53INP2 1 0.00 0 0.69
31 INT240065 KCNIP3 Regulation of Transcription of PDYN 1 0.42 0.88 0.67
32 INT70833 Binding of PDYN and Pnoc 1 0.53 0 0.65
33 INT38820 Binding of MTR and PDYN 1 0.03 0.19 0.65
34 INT77529 PDYN Positive_regulation of Odc1 1 0.02 0 0.63
35 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61
36 INT109256 PDYN Positive_regulation of Binding of CRYGS 1 0.00 0.1 0.61
37 INT34840 Binding of KNG1 and PDYN 1 0.01 0 0.61
38 INT47461 PDYN Regulation of POMC 1 0.01 0 0.6
39 INT240069 KCNIP3 Regulation of Gene_expression of PDYN 1 0.25 0.75 0.59
40 INT72416 Binding of PDYN and El2 1 0.45 0 0.58
41 INT62035 PDYN Regulation of Gene_expression of IGHE 1 0.33 0 0.57
42 INT114647 Fos Positive_regulation of Gene_expression of PDYN 1 0.48 0.52 0.52
43 INT28082 POMC Regulation of PDYN 1 0.04 0.09 0.45
44 INT44520 PDYN Regulation of Localization of Prl 1 0.00 0 0.4
45 INT44513 PDYN Regulation of Localization of CGA 1 0.00 0 0.4
46 INT13715 PDYN Positive_regulation of TYMS 1 0.27 0 0.39
47 INT10825 Binding of PDYN and Tyr 1 0.01 0 0.39
48 INT18089 Binding of GNRH1 and PDYN 1 0.01 0 0.38
49 INT30353 Binding of PDYN and Sst 1 0.02 0 0.37
50 INT18098 PDYN Positive_regulation of Localization of Prl 1 0.00 0 0.37
51 INT20889 PDYN Regulation of Localization of IGKV1D-39 1 0.15 0 0.37
52 INT337115 Tg(CAG-EGFP)D4Nagy Positive_regulation of Gene_expression of PDYN 1 0.04 0.07 0.36
53 INT13548 Binding of PDYN and TALDO1 1 0.40 0 0.35
54 INT37328 Binding of PDYN and Mme 1 0.02 0 0.34
55 INT35180 Binding of STT3A and PDYN 1 0.14 0.37 0.29
56 INT105003 Binding of PDYN and SHMT2 1 0.04 0.49 0.26
57 INT105004 Binding of DRD3 and PDYN 1 0.23 0.49 0.26
58 INT135070 Preb Regulation of Gene_expression of PDYN 1 0.00 0 0.22
59 INT182913 KCNIP3 Negative_regulation of PDYN 1 0.13 0.2 0.14
60 INT133631 IRF6 Negative_regulation of Transcription of PDYN 1 0.17 0 0.03
61 INT18642 Binding of AVP and PDYN 1 0.39 0 0
62 INT182920 Binding of PDYN and VDR 1 0.12 0.07 0
63 INT182934 Binding of PDYN and KCNIP3 1 0.13 0.09 0
64 INT182956 Binding of PDYN and TNFRSF25 1 0.08 0.09 0
65 INT182928 VDR Regulation of PDYN 1 0.09 0.07 0
66 INT18643 Binding of OXT and PDYN 1 0.44 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5173. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5173. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65
2 INT442 Localization of PDYN 99 0.81 11.87 72.75
3 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04
4 INT1430 Regulation of PDYN 88 0.60 16.99 60.32
5 INT1510 Binding of PDYN 94 0.48 4.68 56.44
6 INT5136 Negative_regulation of PDYN 71 0.59 11.22 51.14
7 INT8531 Transcription of PDYN 56 0.72 19.51 30.99
8 INT7644 Positive_regulation of Gene_expression of PDYN 27 0.69 10.19 17.47
9 INT9663 Protein_catabolism of PDYN 43 0.99 0.67 16.15
10 INT12232 Regulation of Gene_expression of PDYN 21 0.60 9.91 12.18
11 INT28770 Negative_regulation of Gene_expression of PDYN 16 0.57 4.95 12.06
12 INT29964 Positive_regulation of Positive_regulation of PDYN 9 0.67 1.56 11.31
13 INT17233 Positive_regulation of Localization of PDYN 9 0.69 2.84 10.06
14 INT8532 Regulation of Transcription of PDYN 10 0.44 4.97 6.95
15 INT18460 Positive_regulation of Transcription of PDYN 11 0.67 2.14 6.61
16 INT17234 Positive_regulation of Negative_regulation of PDYN 4 0.45 0.66 4.89
17 INT9390 Negative_regulation of Negative_regulation of PDYN 5 0.42 1.31 4.54
18 INT103579 Negative_regulation of Positive_regulation of PDYN 2 0.42 1.34 3.77
19 INT18662 Negative_regulation of Binding of PDYN 5 0.57 0.34 3.58
20 INT30701 Regulation of Localization of PDYN 4 0.27 0.31 2.79
21 INT133632 Negative_regulation of Transcription of PDYN 5 0.57 2.79 1.96
22 INT186441 Regulation of Regulation of PDYN 2 0.26 1.81 1.92
23 INT9662 Positive_regulation of Protein_catabolism of PDYN 5 0.57 0 1.9
24 INT29202 Negative_regulation of Regulation of PDYN 1 0.06 0 1.38
25 INT6175 Negative_regulation of Localization of PDYN 3 0.41 0.1 1.37
26 INT29524 Positive_regulation of Binding of PDYN 2 0.45 0 1.19
27 INT10091 Regulation of Protein_catabolism of PDYN 2 0.05 0 1.16
28 INT10686 Regulation of Binding of PDYN 3 0.43 0.61 1.1
29 INT54682 Positive_regulation of Regulation of PDYN 1 0.17 0 1.09
30 INT42734 Negative_regulation of Protein_catabolism of PDYN 2 0.06 0 0.86
31 INT28219 Regulation of Positive_regulation of PDYN 1 0.12 0 0.56
32 INT37642 Phosphorylation of PDYN 1 0.51 0 0.24
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