G:5243

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Official Symbol ABCB1
Aliases CLCS, MDR1, P-GP, PGY1, ABC20, CD243, GP170, MGC163296
EntrezGene 5243
UniProt Coming Soon
Unique Molecular Interactions 21
Total Molecular Interactions 29
Total Single Events 408
Unique Interaction Partners 18

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to ABCB1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to ABCB1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to ABCB1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
2 INT144283 ACP1 Positive_regulation of ABCB1 1 0.63 0.6 0.81
3 INT335514 NR1I2 Regulation of Gene_expression of ABCB1 1 0.66 2.42 0.54
4 INT111837 Binding of ABCB1 and SLC22A3 1 0.35 0 0.31
5 INT95968 OPRD1 Negative_regulation of Gene_expression of ABCB1 1 0.34 0.75 0.21
6 INT95969 OPRD1 Negative_regulation of ABCB1 1 0.34 0.75 0.21
7 INT132897 Binding of ABCB1 and Slco1c1 1 0.03 0 0.2
8 INT113867 Binding of ABCB1 and PGP 1 0.46 1 0.16
9 INT137510 Nfkb1 Positive_regulation of Gene_expression of ABCB1 1 0.17 0.59 0.14
10 INT54470 Binding of DNAH8 and ABCB1 1 0.30 0 0.1
11 INT54471 Positive_regulation of Binding of DNAH8 and ABCB1 1 0.29 0 0.1
12 INT99910 Binding of MTX1 and ABCB1 1 0.25 0.09 0.1
13 INT99476 Binding of CYP3A4 and ABCB1 2 0.28 0 0.08
14 INT177294 Binding of ABCB1 and TNFRSF25 1 0.16 0 0.08
15 INT177295 Binding of CXADR and ABCB1 1 0.30 0 0.05
16 INT177272 Binding of ABCB1 and NR1H4 1 0.02 0 0.04
17 INT197713 CNTN2 Positive_regulation of ABCB1 1 0.01 0.34 0
18 INT276759 ABCB1 Regulation of TOP2A 1 0.04 0.61 0
19 INT335512 NFKB1 Regulation of NFKB1 Positive_regulation of Gene_expression of ABCB1 1 0.44 0.31 0
20 INT97565 JUN Positive_regulation of Gene_expression of ABCB1 1 0.45 0.06 0
21 INT177256 SV2A Positive_regulation of ABCB1 1 0.38 0 0
22 INT177287 CXADR Positive_regulation of ABCB1 1 0.39 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5243. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5243. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88
2 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67
3 INT54473 Binding of ABCB1 30 0.48 8.65 10.38
4 INT13467 Positive_regulation of ABCB1 36 0.68 9.68 8.95
5 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83
6 INT96198 Positive_regulation of Gene_expression of ABCB1 25 0.68 5.89 5.15
7 INT122448 Regulation of Gene_expression of ABCB1 13 0.62 3.67 3.5
8 INT95971 Negative_regulation of Gene_expression of ABCB1 7 0.58 5.61 3.34
9 INT70563 Localization of ABCB1 14 0.78 2.03 3.09
10 INT115665 Transcription of ABCB1 9 0.71 3.69 1.91
11 INT130748 Negative_regulation of Localization of ABCB1 2 0.42 0.71 1.02
12 INT199422 Positive_regulation of Negative_regulation of ABCB1 2 0.49 1.28 0.4
13 INT307279 Positive_regulation of Localization of ABCB1 1 0.05 0 0.25
14 INT83679 Positive_regulation of Binding of ABCB1 1 0.67 0 0.16
15 INT139832 Regulation of Negative_regulation of ABCB1 1 0.44 0 0.08
16 INT311750 Positive_regulation of Positive_regulation of ABCB1 1 0.68 0.13 0.03
17 INT115664 Positive_regulation of Transcription of ABCB1 3 0.37 0.54 0
18 INT104184 Negative_regulation of Negative_regulation of ABCB1 2 0.38 0 0
19 INT165323 Negative_regulation of Transcription of ABCB1 2 0.58 0.62 0
20 INT311749 Regulation of Binding of ABCB1 1 0.44 0 0
21 INT252201 Phosphorylation of ABCB1 1 0.61 0 0
22 INT63497 Protein_catabolism of ABCB1 1 0.24 0.22 0
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