G:5595

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Official Symbol MAPK3
Aliases ERK1, ERT2, ERK-1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, MGC20180, p44-ERK1, p44-MAPK
EntrezGene 5595
UniProt Coming Soon
Unique Molecular Interactions 29
Total Molecular Interactions 30
Total Single Events 228
Unique Interaction Partners 22

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to MAPK3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to MAPK3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to MAPK3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
2 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
3 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
4 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
5 INT169296 PTPLA Positive_regulation of MAPK3 1 0.10 0.15 0.63
6 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
7 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
8 INT131371 MAPK3 Positive_regulation of Il4 1 0.02 0.37 0.51
9 INT131367 MAPK3 Positive_regulation of Bcar3 1 0.00 0.37 0.51
10 INT131370 MAPK3 Positive_regulation of Gene_expression of Il4 1 0.02 0.37 0.51
11 INT102552 HGF Positive_regulation of MAPK3 1 0.38 0.47 0.47
12 INT106396 DYT10 Positive_regulation of MAPK3 1 0.50 0 0.42
13 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
14 INT162045 F2 Positive_regulation of Phosphorylation of MAPK3 1 0.30 0.99 0.3
15 INT134401 Negative_regulation of MAPK3 Negative_regulation of Gene_expression of ARMC3 1 0.19 1.16 0.13
16 INT134399 Negative_regulation of MAPK3 Positive_regulation of Phosphorylation of MAPK8 1 0.39 1.14 0.13
17 INT156829 EGF Positive_regulation of MAPK3 2 0.08 0.87 0.1
18 INT156839 Binding of CYP24A1 and MAPK3 1 0.31 0 0.07
19 INT156835 Binding of MAPK3 and TRPV6 1 0.21 0 0.07
20 INT243318 MAPK3 Negative_regulation of FOS 1 0.04 0.14 0
21 INT342558 FGF9 Positive_regulation of MAPK3 1 0.03 1.21 0
22 INT177917 Positive_regulation of EGF Positive_regulation of Phosphorylation of MAPK3 1 0.04 0.4 0
23 INT254706 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
24 INT254702 Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
25 INT122545 FGF2 Positive_regulation of Positive_regulation of MAPK3 1 0.53 0 0
26 INT177912 EGF Regulation of MAPK3 1 0.02 0.84 0
27 INT254705 Map2k2 Positive_regulation of Phosphorylation of MAPK3 1 0.08 0.86 0
28 INT342557 FGF2 Positive_regulation of MAPK3 1 0.03 1.21 0
29 INT177913 EGF Positive_regulation of Phosphorylation of MAPK3 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5595. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5595. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
2 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
3 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
4 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
5 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18
6 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39
7 INT71783 Positive_regulation of Gene_expression of MAPK3 9 0.59 4.59 3.05
8 INT87288 Positive_regulation of Positive_regulation of MAPK3 5 0.67 1.62 3.04
9 INT87284 Negative_regulation of Positive_regulation of MAPK3 7 0.41 2.65 2.38
10 INT118683 Regulation of Phosphorylation of MAPK3 3 0.44 2.92 1.82
11 INT87282 Regulation of MAPK3 9 0.60 7.61 1.65
12 INT238919 Regulation of Gene_expression of MAPK3 3 0.16 1.6 1.13
13 INT164381 Regulation of Positive_regulation of MAPK3 2 0.60 1.49 1.03
14 INT166018 Protein_catabolism of MAPK3 1 0.23 0.59 0.56
15 INT119081 Negative_regulation of Gene_expression of MAPK3 2 0.41 2 0.33
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