G:5617

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Official Symbol PRL
Aliases none
EntrezGene 5617
UniProt Coming Soon
Unique Molecular Interactions 73
Total Molecular Interactions 93
Total Single Events 1849
Unique Interaction Partners 46

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PRL. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PRL. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PRL. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT32182 PRL Regulation of GHRH 2 0.17 0 1.12
2 INT79094 PDYN Positive_regulation of PRL 1 0.35 0.09 1.07
3 INT33135 Binding of NFKBIL1 and PRL 1 0.09 0.29 1.01
4 INT25155 TRH Positive_regulation of PRL 2 0.50 0.4 1
5 INT32327 POMC Positive_regulation of Localization of PRL 4 0.45 0 0.99
6 INT41659 IL31RA Regulation of PRL 1 0.22 1.07 0.98
7 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94
8 INT35160 GH1 Regulation of PRL 2 0.37 0 0.89
9 INT2000 ASNA1 Positive_regulation of Localization of PRL 1 0.07 0 0.79
10 INT40127 Lhb Regulation of Localization of PRL 1 0.20 0.41 0.75
11 INT40126 PRL Regulation of Localization of Lhb 1 0.20 0.41 0.75
12 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73
13 INT44519 Penk Regulation of PRL 1 0.01 0 0.73
14 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61
15 INT35159 FSHR Regulation of PRL 2 0.34 0 0.6
16 INT35154 PLOD1 Regulation of PRL 2 0.17 0 0.6
17 INT25156 TRH Regulation of PRL 2 0.27 0.81 0.56
18 INT33513 GH1 Positive_regulation of PRL 1 0.30 0 0.53
19 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53
20 INT120852 PRL Positive_regulation of IRF1 1 0.44 0.99 0.51
21 INT44523 Penk Regulation of Gene_expression of PRL 1 0.01 0 0.49
22 INT44521 Penk Regulation of Localization of PRL 1 0.01 0 0.49
23 INT67984 GHRH Regulation of PRL 1 0.22 0 0.49
24 INT182705 NPFF Regulation of Localization of PRL 1 0.03 0 0.48
25 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45
26 INT46008 OPRM1 Regulation of Localization of PRL 1 0.14 0 0.44
27 INT25157 TRH Regulation of TRH Regulation of PRL 1 0.29 0 0.42
28 INT34786 KCNA1 Positive_regulation of Localization of PRL 1 0.05 0 0.4
29 INT78621 PRL Positive_regulation of Localization of INS 2 0.06 0.5 0.39
30 INT285746 IL6 Regulation of Localization of PRL 1 0.08 1.51 0.39
31 INT285749 IL6 Positive_regulation of Localization of PRL 1 0.08 1.51 0.39
32 INT285750 IL1B Positive_regulation of Localization of PRL 1 0.05 1.51 0.39
33 INT285744 IL1B Regulation of Localization of PRL 1 0.05 1.51 0.39
34 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37
35 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37
36 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33
37 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33
38 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33
39 INT40855 GGH Regulation of PRL 1 0.10 0 0.32
40 INT285748 PRL Positive_regulation of Positive_regulation of C6orf25 1 0.01 1.01 0.31
41 INT89895 LHB Positive_regulation of Localization of PRL 1 0.09 0 0.29
42 INT89911 PLOD1 Positive_regulation of Localization of PRL 1 0.12 0 0.29
43 INT89903 AVP Positive_regulation of Localization of PRL 1 0.40 0 0.29
44 INT36571 MDK Positive_regulation of Localization of PRL 1 0.04 0.19 0.29
45 INT89899 PRL Positive_regulation of Localization of POMC 1 0.33 0 0.28
46 INT43838 POMC Positive_regulation of PRL 1 0.36 0 0.28
47 INT43839 Regulation of POMC Positive_regulation of PRL 1 0.32 0 0.28
48 INT89908 GH1 Positive_regulation of Localization of PRL 1 0.11 0 0.27
49 INT89896 GHRH Positive_regulation of Localization of PRL 1 0.30 0 0.27
50 INT89905 PRL Positive_regulation of Localization of GH1 1 0.11 0 0.27
51 INT120856 PRL Positive_regulation of Localization of IL10 1 0.29 0.5 0.26
52 INT120855 PRL Positive_regulation of Localization of IL12A 1 0.43 0.5 0.26
53 INT44440 GNRH1 Positive_regulation of Localization of PRL 1 0.08 0.19 0.26
54 INT120850 PRL Positive_regulation of Localization of TNF 1 0.27 0.5 0.26
55 INT120853 PRL Positive_regulation of Positive_regulation of IRF1 1 0.41 0.49 0.25
56 INT120849 PRL Positive_regulation of NFKB1 1 0.07 0.49 0.25
57 INT44522 Gnrh1 Regulation of PRL 1 0.00 0 0.24
58 INT39738 PRL Regulation of Localization of GH1 1 0.37 0.6 0.24
59 INT11790 CA2 Regulation of Localization of PRL 1 0.23 0 0.18
60 INT11791 TRH Regulation of Localization of PRL 1 0.18 0 0.17
61 INT29876 OXTR Regulation of Regulation of PRL 1 0.15 0 0.12
62 INT29873 OXTR Regulation of PRL 1 0.25 0 0.12
63 INT243464 POU1F1 Regulation of PRL 1 0.28 1.26 0.08
64 INT100127 ADM Positive_regulation of PRL 1 0.28 0.51 0.08
65 INT328312 GHS Positive_regulation of Localization of PRL 1 0.02 0.21 0.03
66 INT215904 IL36B Regulation of PRL 1 0.01 0.22 0.03
67 INT112552 Binding of PRL and Prl 1 0.39 0 0
68 INT264663 Binding of ESR1 and PRL 1 0.22 0.18 0
69 INT264662 ESR1 Regulation of Gene_expression of PRL 1 0.43 0.21 0
70 INT47482 PRL Regulation of Gene_expression of LGALS1 1 0.19 0 0
71 INT212014 RAD51D Positive_regulation of Gene_expression of PRL 1 0.06 0.77 0
72 INT334281 NR2E3 Negative_regulation of Gene_expression of PRL 1 0.04 0 0
73 INT212009 Binding of PRL and PTHLH 1 0.32 0.48 0
74 INT264661 ESR1 Positive_regulation of PRL 1 0.43 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5617. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5617. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT425 Localization of PRL 455 0.81 189.64 144.8
2 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31
3 INT253 Regulation of PRL 184 0.62 47.27 65.79
4 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41
5 INT918 Positive_regulation of Localization of PRL 90 0.70 23.97 40.3
6 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13
7 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01
8 INT1578 Negative_regulation of Localization of PRL 52 0.59 20.62 17.18
9 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44
10 INT4487 Positive_regulation of Positive_regulation of PRL 27 0.70 8.06 8.09
11 INT21067 Regulation of Regulation of PRL 11 0.60 2 5.31
12 INT29290 Regulation of Gene_expression of PRL 13 0.49 6.46 5.23
13 INT6021 Binding of PRL 18 0.48 12.55 4.3
14 INT922 Regulation of Positive_regulation of PRL 7 0.60 3.57 3.95
15 INT4485 Negative_regulation of Positive_regulation of PRL 11 0.43 4.24 3.89
16 INT1577 Negative_regulation of Gene_expression of PRL 24 0.59 7.7 3.15
17 INT34891 Transcription of PRL 4 0.72 0.69 2.36
18 INT26341 Positive_regulation of Regulation of PRL 4 0.70 1.43 1.92
19 INT232445 Positive_regulation of Transcription of PRL 1 0.50 0 1.32
20 INT39955 Positive_regulation of Negative_regulation of PRL 3 0.70 0.47 0.9
21 INT42496 Regulation of Negative_regulation of PRL 1 0.45 0.36 0.69
22 INT34889 Regulation of Transcription of PRL 2 0.42 0.55 0.67
23 INT33518 Negative_regulation of Regulation of PRL 2 0.39 0.14 0.41
24 INT232449 Negative_regulation of Transcription of PRL 1 0.59 0 0.3
25 INT232452 Positive_regulation of Binding of PRL 1 0.50 0.18 0.27
26 INT215908 Negative_regulation of Binding of PRL 1 0.09 0.4 0.05
27 INT330963 Phosphorylation of PRL 1 0.42 2.37 0
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