G:5624

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Official Symbol PROC
Aliases PC, APC, PROC1, THPH3, THPH4
EntrezGene 5624
UniProt Coming Soon
Unique Molecular Interactions 50
Total Molecular Interactions 89
Total Single Events 642
Unique Interaction Partners 44

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PROC. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PROC. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PROC. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
2 INT139722 PROC Positive_regulation of CDCP1 1 0.00 1.61 1.29
3 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
4 INT298730 PROC Positive_regulation of Gene_expression of Ngf 1 0.00 0.6 0.74
5 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
6 INT145491 PROC Positive_regulation of Cpox 1 0.00 1.08 0.58
7 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56
8 INT298729 PROC Positive_regulation of Set 1 0.00 0.76 0.55
9 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
10 INT95644 PROC Negative_regulation of NPEPPS 1 0.00 1.24 0.35
11 INT195669 Binding of F2 and PROC 1 0.04 1.44 0.31
12 INT191799 PROC Negative_regulation of Binding of F2r 1 0.00 0.92 0.3
13 INT282646 Binding of PROC and PROCR 1 0.40 0.99 0.26
14 INT348364 PROC Negative_regulation of TNF 1 0.01 0.89 0.23
15 INT250779 PROC Regulation of IRF6 Positive_regulation of AMIGO2 1 0.00 0.74 0.22
16 INT69390 Binding of PENK and PROC 1 0.00 0.22 0.21
17 INT348363 PCTP Positive_regulation of PROC 1 0.01 0.41 0.2
18 INT348372 Binding of PROC and Stard10 1 0.01 0.41 0.2
19 INT117517 PROC Positive_regulation of PTGS2 1 0.01 0.61 0.19
20 INT210029 PROC Negative_regulation of PRTN3 1 0.00 1.06 0.18
21 INT326390 Binding of PROC and Ezr 1 0.00 1 0.17
22 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15
23 INT195662 Binding of PROC and KAT8 1 0.10 2.25 0.12
24 INT326387 Binding of PROC and Rhoa 1 0.00 0.59 0.12
25 INT266683 IL1B Positive_regulation of Gene_expression of PROC 1 0.00 1.62 0.11
26 INT65958 PROC Positive_regulation of NDUFA1 1 0.00 0.31 0.09
27 INT195777 THBD Positive_regulation of PROC 1 0.00 1.26 0.08
28 INT326388 Binding of PROC and Slc9a3r2 1 0.00 1.26 0.06
29 INT266082 PROC Regulation of Localization of VEGFA 1 0.00 0.84 0.05
30 INT222684 TEAD1 Negative_regulation of PROC 1 0.01 0.39 0.05
31 INT348365 Binding of PROC and TNF 1 0.00 0.19 0.05
32 INT262256 Binding of PROC and AMIGO2 1 0.00 0.72 0.04
33 INT213422 MITF Negative_regulation of PROC 1 0.00 0.52 0.03
34 INT324593 Binding of PROC and RNASEL 1 0.01 0.91 0.03
35 INT260318 Binding of PROC and Anxa5 1 0.00 0 0
36 INT212527 Binding of PROC and Crp 1 0.00 1.5 0
37 INT208364 Hdl1 Positive_regulation of Localization of PROC 1 0.00 1.13 0
38 INT208365 Apoc3 Positive_regulation of Localization of PROC 1 0.00 1.13 0
39 INT326389 Binding of PROC and Eras 1 0.00 0 0
40 INT297740 Cbr1 Negative_regulation of Positive_regulation of PROC 1 0.00 0.42 0
41 INT55160 Binding of PROC and REL 1 0.01 0.09 0
42 INT326386 Binding of PROC and Gopc 1 0.00 0 0
43 INT195661 Binding of APC and PROC 1 0.23 0.89 0
44 INT55166 Binding of PROC and RELA 1 0.01 0.09 0
45 INT344000 PROC Positive_regulation of PRNP 1 0.00 0.07 0
46 INT234440 Binding of PROC and RARA 1 0.00 0.73 0
47 INT350168 Binding of DMD and PROC 1 0.00 0.67 0
48 INT297741 Cbr1 Negative_regulation of PROC 1 0.00 0.4 0
49 INT212526 Binding of PROC and Apcs 1 0.01 2.54 0
50 INT195659 APC Positive_regulation of Gene_expression of PROC 1 0.26 0.31 0
51 INT341628 Binding of ADAR and PROC 1 0.03 5.01 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5624. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5624. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75
2 INT4535 Localization of PROC 106 0.73 76.24 21.1
3 INT1767 Positive_regulation of PROC 83 0.67 54.14 17
4 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79
5 INT1168 Binding of PROC 62 0.38 44.15 9.04
6 INT4534 Regulation of PROC 38 0.33 19.81 8.99
7 INT16461 Negative_regulation of Gene_expression of PROC 13 0.24 4.39 2.17
8 INT55962 Positive_regulation of Localization of PROC 9 0.20 7.76 1.87
9 INT69000 Positive_regulation of Gene_expression of PROC 6 0.20 5.87 1.84
10 INT88523 Positive_regulation of Negative_regulation of PROC 4 0.01 3.76 1.76
11 INT1768 Negative_regulation of Positive_regulation of PROC 5 0.41 2.8 1.51
12 INT55979 Protein_catabolism of PROC 8 0.22 2.8 1.49
13 INT65319 Transcription of PROC 6 0.01 2.96 1.44
14 INT55980 Positive_regulation of Protein_catabolism of PROC 1 0.16 1.64 1.04
15 INT56406 Regulation of Gene_expression of PROC 4 0.05 1.52 0.79
16 INT120012 Negative_regulation of Transcription of PROC 1 0.00 0.97 0.71
17 INT305315 Positive_regulation of Positive_regulation of PROC 3 0.49 1.52 0.64
18 INT55981 Negative_regulation of Binding of PROC 1 0.15 0 0.48
19 INT195677 Regulation of Positive_regulation of PROC 1 0.22 1.57 0.06
20 INT212047 Phosphorylation of PROC 2 0.13 1.41 0
21 INT195682 Positive_regulation of Binding of PROC 1 0.25 0 0
22 INT217203 Positive_regulation of Phosphorylation of PROC 1 0.01 1.96 0
23 INT56405 Negative_regulation of Localization of PROC 1 0.08 0 0
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