G:5644

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Official Symbol PRSS1
Aliases TRP1, TRY1, TRY4, TRYP1, FLJ57296, MGC120175, MGC149362, DKFZp779A0837
EntrezGene 5644
UniProt Coming Soon
Unique Molecular Interactions 50
Total Molecular Interactions 70
Total Single Events 364
Unique Interaction Partners 33

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PRSS1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PRSS1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PRSS1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36536 PRSS1 Positive_regulation of PENK 1 0.24 0.86 4.39
2 INT36535 PRSS1 Positive_regulation of Regulation of PENK 1 0.23 0.54 3.06
3 INT23280 PRSS1 Positive_regulation of Penk 1 0.05 1.53 2.74
4 INT104975 MITF Regulation of Transcription of PRSS1 1 0.68 0.35 1.46
5 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29
6 INT35862 PRSS1 Regulation of Localization of GBE1 1 0.00 0.35 0.59
7 INT201512 Binding of PRSS1 and hcp 1 0.09 1.9 0.57
8 INT229127 SPINK1 Positive_regulation of PRSS1 1 0.53 1.59 0.48
9 INT144110 PRSS1 Positive_regulation of Gene_expression of IL8 1 0.21 1.38 0.48
10 INT229128 Binding of CP and PRSS1 1 0.14 0.77 0.47
11 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45
12 INT72348 Mbp Positive_regulation of Localization of PRSS1 1 0.01 0.22 0.41
13 INT72345 MBP Positive_regulation of Localization of PRSS1 1 0.00 0.22 0.41
14 INT35861 PRSS1 Regulation of Localization of CCK 1 0.26 0.17 0.33
15 INT35859 PRSS1 Regulation of Regulation of CCK 1 0.13 0.18 0.3
16 INT35863 PRSS1 Regulation of Positive_regulation of CCK 1 0.22 0.18 0.3
17 INT35858 PRSS1 Regulation of Positive_regulation of SCT 1 0.17 0.18 0.3
18 INT115514 Binding of PRSS1 and KRT79 1 0.02 1.19 0.26
19 INT229129 SPINK1 Negative_regulation of PRSS1 1 0.49 0.79 0.24
20 INT46285 SCT Positive_regulation of PRSS1 1 0.16 0.1 0.19
21 INT46283 CCK Positive_regulation of PRSS1 1 0.06 0.1 0.19
22 INT115510 Binding of PRSS1 and PRSS2 1 0.41 0.8 0.18
23 INT35860 PRSS1 Regulation of Localization of SCT 1 0.10 0.08 0.16
24 INT199129 Ctsb Positive_regulation of PRSS1 1 0.01 0.9 0.15
25 INT106995 PRSS1 Positive_regulation of SPG21 1 0.04 0.29 0.14
26 INT107004 PRSS1 Positive_regulation of PAR4 1 0.08 0.28 0.14
27 INT107000 PRSS1 Positive_regulation of NR1I2 1 0.08 0.28 0.13
28 INT107005 F2 Positive_regulation of PRSS1 1 0.00 0.28 0.13
29 INT312568 AMBP Regulation of Negative_regulation of PRSS1 1 0.02 0.95 0.12
30 INT115512 KRT79 Negative_regulation of Positive_regulation of PRSS1 1 0.02 0.72 0.12
31 INT115513 PRSS1 Positive_regulation of PRSS2 1 0.40 0.71 0.12
32 INT3326 PRSS1 Positive_regulation of ATP6AP2 1 0.01 0 0.11
33 INT341529 PRSS1 Positive_regulation of Gene_expression of F2RL1 1 0.06 0 0.11
34 INT341543 PRSS1 Positive_regulation of Transcription of F2RL1 1 0.06 0 0.11
35 INT229393 Negative_regulation of PRSS1 Negative_regulation of Gene_expression of IL8 1 0.00 0.86 0.11
36 INT171645 Negative_regulation of CTSB Positive_regulation of PRSS1 1 0.44 0.36 0.1
37 INT171644 CTSB Positive_regulation of PRSS1 1 0.52 0.36 0.1
38 INT120700 PRSS1 Positive_regulation of ICAM1 1 0.15 0.29 0.1
39 INT171648 Binding of CTSB and PRSS1 1 0.27 0.42 0.1
40 INT115507 Binding of PRSS1 and KRT79 Positive_regulation of Positive_regulation of PRSS2 1 0.03 0.46 0.09
41 INT199130 PRSS1 Positive_regulation of Prss1 1 0.15 0.8 0.09
42 INT184164 Binding of PRSS1 and SAA@ 1 0.02 0.39 0.07
43 INT107859 PRSS1 Positive_regulation of EDNRA 1 0.03 0.69 0.04
44 INT45690 PRSS1 Positive_regulation of NRD1 1 0.00 0 0.03
45 INT45687 PRSS1 Negative_regulation of NRD1 1 0.00 0 0.03
46 INT45685 PRSS1 Negative_regulation of PRSS1 Positive_regulation of NRD1 1 0.00 0 0.03
47 INT201490 Gene_expression of SPINK1 Negative_regulation of PRSS1 1 0.44 0.82 0.03
48 INT45689 Negative_regulation of PRSS1 Positive_regulation of NRD1 1 0.00 0 0.03
49 INT170885 Binding of PRSS1 and RHBDD2 1 0.01 0.4 0
50 INT293055 Binding of ANXA5 and PRSS1 1 0.00 0.59 0
51 INT171646 PRSS1 Positive_regulation of NXF1 1 0.34 0.53 0
52 INT351465 PRSS1 Regulation of Gene_expression of IKBKAP 1 0.00 0.65 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5644. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5644. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48
2 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33
3 INT12240 Negative_regulation of PRSS1 46 0.57 29.5 10.77
4 INT22782 Localization of PRSS1 25 0.81 14.44 7.34
5 INT24946 Binding of PRSS1 23 0.47 16.75 6.41
6 INT3327 Protein_catabolism of PRSS1 22 1.00 6.96 4.29
7 INT35864 Regulation of PRSS1 19 0.61 8.14 3.63
8 INT12241 Negative_regulation of Positive_regulation of PRSS1 6 0.43 5.39 3.22
9 INT104980 Transcription of PRSS1 5 0.69 3.54 2.12
10 INT45692 Positive_regulation of Gene_expression of PRSS1 8 0.49 4.07 1.73
11 INT39519 Positive_regulation of Localization of PRSS1 6 0.69 3.78 1.52
12 INT3333 Positive_regulation of Protein_catabolism of PRSS1 3 0.49 2.23 1.29
13 INT91815 Positive_regulation of Positive_regulation of PRSS1 6 0.49 3.79 0.75
14 INT118133 Negative_regulation of Gene_expression of PRSS1 2 0.50 3.58 0.69
15 INT100731 Negative_regulation of Localization of PRSS1 2 0.14 2.17 0.47
16 INT36553 Regulation of Gene_expression of PRSS1 2 0.13 0.82 0.35
17 INT108283 Negative_regulation of Binding of PRSS1 2 0.28 0.82 0.31
18 INT171651 Regulation of Positive_regulation of PRSS1 1 0.60 1.07 0.16
19 INT201509 Regulation of Protein_catabolism of PRSS1 1 0.61 1.2 0.14
20 INT171653 Positive_regulation of Negative_regulation of PRSS1 2 0.49 1.27 0.11
21 INT95361 Negative_regulation of Protein_catabolism of PRSS1 1 0.43 0.66 0.08
22 INT201510 Negative_regulation of Negative_regulation of PRSS1 1 0.37 0.78 0.04
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