G:5663

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Official Symbol PSEN1
Aliases AD3, FAD, PS1, PS-1, S182
EntrezGene 5663
UniProt Coming Soon
Unique Molecular Interactions 8
Total Molecular Interactions 11
Total Single Events 202
Unique Interaction Partners 8

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PSEN1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PSEN1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PSEN1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
2 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
3 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
4 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
5 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
6 INT193968 Binding of PSEN1 and Ps 1 0.07 0.66 0
7 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
8 INT334645 Binding of PSEN1 and HM13 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5663. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5663. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
2 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
3 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
4 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
5 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
6 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
7 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
8 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
9 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
10 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
11 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
12 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
13 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
14 INT234250 Positive_regulation of Negative_regulation of PSEN1 1 0.41 0 0
15 INT193934 Positive_regulation of Binding of PSEN1 1 0.49 0.92 0
16 INT177774 Transcription of PSEN1 1 0.33 0.09 0
17 INT234258 Negative_regulation of Phosphorylation of PSEN1 1 0.35 0.49 0
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