G:5728

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Official Symbol PTEN
Aliases BZS, DEC, GLM2, MHAM, TEP1, MMAC1, PTEN1, 10q23del, MGC11227
EntrezGene 5728
UniProt Coming Soon
Unique Molecular Interactions 23
Total Molecular Interactions 25
Total Single Events 202
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PTEN. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PTEN. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PTEN. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
2 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
3 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
4 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
5 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
6 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
7 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
8 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09
9 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
10 INT221815 PPARA Negative_regulation of PTEN 1 0.15 0.5 0.05
11 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03
12 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
13 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0
14 INT348723 ED Positive_regulation of PTEN 1 0.04 1.3 0
15 INT313885 XRCC1 Positive_regulation of Localization of PTEN 1 0.00 0.65 0
16 INT293802 PTEN Regulation of PIK3CG 1 0.03 0.07 0
17 INT351682 Fut1 Positive_regulation of PTEN 1 0.01 1.81 0
18 INT223574 PTEN Negative_regulation of AKT1 1 0.06 0.56 0
19 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0
20 INT223579 PTEN Negative_regulation of PIK3CG 1 0.18 0.56 0
21 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0
22 INT293804 PTEN Regulation of AKT1 1 0.04 0.07 0
23 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5728. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5728. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
2 INT192676 Binding of PTEN 14 0.46 10.58 3.06
3 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
4 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
5 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
6 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
7 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75
8 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63
9 INT161322 Localization of PTEN 9 0.73 5.65 0.57
10 INT176146 Positive_regulation of Localization of PTEN 3 0.36 1.69 0.5
11 INT263819 Regulation of Gene_expression of PTEN 1 0.25 0.63 0.32
12 INT133488 Negative_regulation of Phosphorylation of PTEN 4 0.41 1.88 0.26
13 INT183242 Negative_regulation of Gene_expression of PTEN 6 0.55 3.81 0.16
14 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12
15 INT176144 Positive_regulation of Phosphorylation of PTEN 1 0.36 0.29 0.04
16 INT315882 Regulation of Negative_regulation of PTEN 2 0.44 1.39 0
17 INT304062 Regulation of Localization of PTEN 1 0.43 1.29 0
18 INT351091 Negative_regulation of Binding of PTEN 1 0.09 0.23 0
19 INT334324 Positive_regulation of Negative_regulation of PTEN 1 0.41 0.81 0
20 INT176158 Regulation of Positive_regulation of PTEN 1 0.32 0.23 0
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