G:5732

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Official Symbol PTGER2
Aliases EP2
EntrezGene 5732
UniProt Coming Soon
Unique Molecular Interactions 158
Total Molecular Interactions 202
Total Single Events 1326
Unique Interaction Partners 85

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PTGER2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PTGER2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PTGER2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
2 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
3 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
4 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
5 INT25113 RYBP Negative_regulation of Binding of PTGER2 1 0.05 0 1.02
6 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 1.47 0.94
7 INT73492 PTGER2 Positive_regulation of Gene_expression of IL4 1 0.08 1.11 0.87
8 INT124743 ARSA Negative_regulation of PTGER2 1 0.03 0.15 0.85
9 INT124744 ARSA Negative_regulation of Gene_expression of PTGER2 1 0.03 0.15 0.85
10 INT65011 IL1B Positive_regulation of PTGER2 4 0.08 0.92 0.82
11 INT203164 PTGER2 Regulation of ALOX5 1 0.00 0.9 0.78
12 INT203171 PTGER2 Negative_regulation of ALOX5 1 0.01 0.89 0.77
13 INT74941 IL1B Positive_regulation of Gene_expression of PTGER2 1 0.08 0.48 0.72
14 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7
15 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
16 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
17 INT193218 Binding of PTGER1 and PTGER2 3 0.12 2.31 0.66
18 INT312105 ELANE Positive_regulation of Localization of PTGER2 4 0.03 1.3 0.64
19 INT94262 IL1B Positive_regulation of Localization of PTGER2 1 0.22 0.8 0.49
20 INT67528 PTGER2 Positive_regulation of Gene_expression of IL6 2 0.10 1.38 0.45
21 INT48715 PTGER2 Regulation of Gene_expression of SERPINE1 1 0.21 0.6 0.44
22 INT193217 Binding of PTGER2 and PTGER3 2 0.10 1.31 0.43
23 INT196348 PTGER2 Negative_regulation of Negative_regulation of MMP2 1 0.01 0.29 0.43
24 INT220193 PTGER2 Regulation of PTGES 1 0.06 0.66 0.41
25 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
26 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 0.03 0.67 0.38
27 INT229041 Gene_expression of IL32 Negative_regulation of Gene_expression of PTGER2 1 0.01 1.17 0.38
28 INT48714 PTGER2 Negative_regulation of Gene_expression of SERPINE1 1 0.15 0.28 0.38
29 INT74938 Negative_regulation of IL1B Positive_regulation of PTGER2 1 0.07 0.23 0.36
30 INT196644 PTGER2 Positive_regulation of Gene_expression of NA 1 0.00 0.93 0.35
31 INT73494 PTGER2 Positive_regulation of Gene_expression of IL12A 1 0.05 0.51 0.33
32 INT73493 PTGER2 Negative_regulation of Gene_expression of IL12A 1 0.04 0.51 0.33
33 INT312099 ELANE Positive_regulation of Gene_expression of PTGER2 1 0.02 0.64 0.32
34 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32
35 INT295725 PTGER2 Positive_regulation of RAC2 1 0.05 1.92 0.32
36 INT294115 IDO1 Positive_regulation of PTGER2 1 0.02 0.36 0.31
37 INT294117 HGF Positive_regulation of PTGER2 1 0.02 0.36 0.31
38 INT102869 PTGER2 Negative_regulation of Transcription of IL6 1 0.17 0.42 0.31
39 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
40 INT203169 CPOX Regulation of Gene_expression of PTGER2 2 0.00 0.48 0.29
41 INT220194 PTGER2 Negative_regulation of COL2A1 1 0.26 0.55 0.29
42 INT196621 PTGER2 Negative_regulation of Gene_expression of DNAH8 1 0.00 0.33 0.28
43 INT196631 PTGER2 Negative_regulation of NFKB1 1 0.00 0.32 0.28
44 INT116592 CPOX Regulation of PTGER2 1 0.02 0.45 0.28
45 INT116591 CASP1 Positive_regulation of PTGER2 1 0.01 0.46 0.28
46 INT34231 PTGER2 Positive_regulation of Gene_expression of TIMP1 1 0.13 0.23 0.27
47 INT278952 MST1 Regulation of Gene_expression of PTGER2 1 0.00 0.41 0.25
48 INT175322 Oxt Positive_regulation of Gene_expression of PTGER2 1 0.00 0.09 0.25
49 INT203165 Binding of IL10 and PTGER2 1 0.01 0.5 0.25
50 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25
51 INT65015 IL6 Negative_regulation of Gene_expression of PTGER2 1 0.09 0.17 0.24
52 INT92581 IGF1R Positive_regulation of Gene_expression of PTGER2 1 0.09 0.79 0.24
53 INT271001 Binding of PTGER2 and Aia1 1 0.00 1.28 0.23
54 INT213061 PTGER2 Regulation of Gene_expression of MMP9 1 0.03 0.25 0.23
55 INT203176 PTGER2 Regulation of Gene_expression of Lts1 1 0.00 0.37 0.23
56 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
57 INT65013 SOS1 Positive_regulation of Gene_expression of PTGER2 1 0.09 0.16 0.22
58 INT196629 PTGER2 Negative_regulation of Gene_expression of NA 1 0.00 0.24 0.22
59 INT220192 PTGER2 Negative_regulation of Positive_regulation of TIMP1 1 0.04 0.99 0.22
60 INT257989 PTGER2 Positive_regulation of RASGRP1 1 0.01 0.61 0.21
61 INT176622 Binding of MMP3 and PTGER2 1 0.02 0.3 0.21
62 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
63 INT102870 PTGER2 Regulation of IL1A 1 0.11 0.28 0.2
64 INT257985 PTGER2 Positive_regulation of MAPK1 1 0.04 0.61 0.2
65 INT231639 Binding of PTGER2 and PTGS2 1 0.00 0.44 0.19
66 INT314273 Uvbi1 Positive_regulation of Gene_expression of PTGER2 1 0.00 0.45 0.19
67 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18
68 INT220190 PTGER2 Regulation of COL2A1 1 0.32 0.92 0.18
69 INT220191 Binding of COL2A1 and PTGER2 1 0.22 0.35 0.18
70 INT314270 CPOX Negative_regulation of Gene_expression of PTGER2 1 0.01 0.15 0.17
71 INT207340 PTGER2 Negative_regulation of Gene_expression of CYP27A1 1 0.00 0 0.17
72 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
73 INT257986 Binding of PTGER2 and GOPC 1 0.04 0.42 0.16
74 INT278947 PTGER2 Regulation of Gene_expression of IL8 1 0.04 0.32 0.16
75 INT176623 Binding of PTGER2 and NDRG1 1 0.00 0.1 0.16
76 INT92580 IGF2 Positive_regulation of Gene_expression of PTGER2 1 0.07 0.43 0.15
77 INT176621 PTGS2 Regulation of Gene_expression of PTGER2 1 0.00 0.09 0.15
78 INT92583 IGF2 Positive_regulation of Transcription of PTGER2 1 0.07 0.43 0.15
79 INT92582 IGF1R Positive_regulation of Transcription of PTGER2 1 0.09 0.43 0.15
80 INT207332 PTGER2 Negative_regulation of ZNF398 Regulation of CYP27A1 1 0.00 0 0.14
81 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
82 INT207341 PTGER2 Negative_regulation of CPOX 1 0.01 0 0.14
83 INT207346 PTGER2 Negative_regulation of Negative_regulation of CYP27A1 1 0.00 0 0.14
84 INT196648 PTGER2 Regulation of DNAH8 1 0.00 0.14 0.12
85 INT266660 PTGER2 Positive_regulation of Gene_expression of MMP9 1 0.06 0.08 0.12
86 INT220197 PTGER2 Negative_regulation of TIMP1 1 0.03 0.23 0.12
87 INT196636 PTGER2 Regulation of NA 1 0.00 0.14 0.12
88 INT257976 Positive_regulation of EGFR Positive_regulation of PTGER2 Positive_regulation of RASGRP1 1 0.00 0.31 0.11
89 INT312116 Negative_regulation of PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 0.2 0.1
90 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1
91 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1
92 INT312121 Negative_regulation of PTGER2 Regulation of Gene_expression of ALOX5 1 0.02 0.2 0.1
93 INT136499 PTGER2 Positive_regulation of TRPC7 1 0.13 0.52 0.09
94 INT220195 PTGER2 Negative_regulation of Localization of COL2A1 1 0.26 0.51 0.09
95 INT346304 Col2a1 Positive_regulation of Localization of PTGER2 1 0.00 0.18 0.09
96 INT302167 PTGER2 Positive_regulation of EGFR 1 0.10 3.08 0.09
97 INT314264 Negative_regulation of CPOX Negative_regulation of Gene_expression of PTGER2 1 0.01 0.15 0.09
98 INT196640 PTGER2 Negative_regulation of DNAH8 1 0.00 0.46 0.08
99 INT196611 PTGER2 Negative_regulation of NA 1 0.00 0.46 0.08
100 INT337181 Binding of IL8 and PTGER2 1 0.01 0.5 0.08
101 INT314265 PTGER2 Positive_regulation of Gene_expression of PTGES2 1 0.00 0.19 0.08
102 INT231638 HR Positive_regulation of Gene_expression of PTGER2 1 0.00 0 0.08
103 INT171272 TNFSF12 Positive_regulation of PTGER2 1 0.00 0.57 0.08
104 INT337173 PTGER2 Positive_regulation of Gene_expression of CD83 1 0.02 0.63 0.08
105 INT294310 PTGER2 Positive_regulation of Gene_expression of IL11 1 0.06 0.12 0.08
106 INT312087 PTGER2 Regulation of Gene_expression of ALOX5 1 0.01 0.13 0.07
107 INT231631 NUCB1 Positive_regulation of Gene_expression of PTGER2 1 0.05 0 0.07
108 INT302152 PTGER2 Positive_regulation of EMR1 1 0.01 2.02 0.07
109 INT171275 IL8 Positive_regulation of PTGER2 1 0.01 0.05 0.07
110 INT337166 PTGER2 Positive_regulation of Gene_expression of CD40 1 0.02 0.77 0.07
111 INT92584 Negative_regulation of PIK3C3 Negative_regulation of Gene_expression of PTGER2 1 0.01 0.46 0.07
112 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06
113 INT171286 TNFSF12 Positive_regulation of Gene_expression of PTGER2 1 0.00 0 0.06
114 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
115 INT314274 Uvbi1 Regulation of Gene_expression of PTGER2 1 0.00 0.18 0.06
116 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06
117 INT302165 PTGER2 Positive_regulation of Localization of EGFR 1 0.06 1.73 0.05
118 INT295715 PTGER2 Regulation of Localization of FGF2 1 0.02 0.6 0.05
119 INT295719 VEGFA Regulation of Localization of PTGER2 1 0.02 0.6 0.05
120 INT296749 PTGER2 Positive_regulation of PTGER1 1 0.25 0 0.05
121 INT257988 PTGER2 Regulation of Gene_expression of PTGER1 1 0.15 0.4 0.05
122 INT302140 PTGER2 Positive_regulation of VEGFA 1 0.11 1.87 0.05
123 INT231634 NUCB1 Positive_regulation of Binding of PTGER2 1 0.05 0 0.04
124 INT224734 PTGER2 Positive_regulation of IL1B 1 0.02 0.79 0.04
125 INT178091 EDN1 Positive_regulation of Gene_expression of PTGER2 1 0.01 0.74 0.04
126 INT258006 PTGER2 Positive_regulation of Phosphorylation of Prkaca 1 0.03 0.13 0.04
127 INT224735 Positive_regulation of PTGER2 Positive_regulation of IL1B 1 0.02 0.81 0.04
128 INT171258 IL6 Positive_regulation of PTGER2 1 0.01 0.38 0.04
129 INT171270 TNFSF12 Negative_regulation of Gene_expression of PTGER2 1 0.00 0 0.04
130 INT302166 Positive_regulation of PTGER2 Positive_regulation of EGFR 1 0.07 1.49 0.04
131 INT171288 TNF Positive_regulation of PTGER2 1 0.03 0.38 0.04
132 INT295718 Binding of PTGER2 and Positive_regulation of Positive_regulation of SP1 1 0.02 0.58 0.04
133 INT220196 Binding of PTGER2 and Negative_regulation of Gene_expression of COL2A1 1 0.26 0.77 0.04
134 INT302153 PTGER2 Positive_regulation of Localization of AREG 1 0.06 1.1 0.03
135 INT207356 PTGER2 Regulation of Gene_expression of CYP27A1 1 0.00 0.05 0.03
136 INT314268 SUPT4H1 Positive_regulation of Gene_expression of PTGER2 1 0.01 0.13 0.03
137 INT257992 PTGER2 Negative_regulation of GOPC 1 0.04 0 0.03
138 INT231636 NUCB1 Regulation of Gene_expression of PTGER2 1 0.03 0 0.03
139 INT294303 PTGER2 Positive_regulation of Localization of IL11 1 0.04 0.08 0.03
140 INT312076 PTGER2 Regulation of ELANE Regulation of ALOX5 1 0.01 0.06 0.03
141 INT312077 PTGER2 Regulation of ELANE Regulation of ALOX5AP 1 0.02 0.06 0.03
142 INT302126 PTGER2 Positive_regulation of SRC 1 0.11 1.08 0.03
143 INT294301 PTGER2 Positive_regulation of IL11 1 0.04 0.08 0.03
144 INT231633 HR Positive_regulation of Positive_regulation of PTGER2 1 0.00 0 0.03
145 INT231637 Gene_expression of HR Positive_regulation of Gene_expression of PTGER2 1 0.00 0.05 0.03
146 INT295702 PTGER2 Positive_regulation of Racgap1 1 0.05 0.22 0
147 INT295710 PTGER2 Regulation of Positive_regulation of RAC1 1 0.01 1.62 0
148 INT231632 HR Positive_regulation of Binding of PTGER2 1 0.00 0 0
149 INT302179 PTGER2 Positive_regulation of Phosphorylation of IFI27 1 0.05 0.75 0
150 INT295706 PTGER2 Regulation of Regulation of RHOA 1 0.01 0.61 0
151 INT258007 PTGER2 Negative_regulation of Phosphorylation of Prkaca 1 0.02 0 0
152 INT295714 PTGER2 Positive_regulation of RHOA 1 0.01 0.34 0
153 INT34763 Binding of AGT and PTGER2 1 0.04 0.24 0
154 INT298586 PTGER2 Regulation of Gene_expression of TNFSF11 1 0.06 0 0
155 INT312120 ELANE Regulation of Localization of PTGER2 1 0.03 0 0
156 INT298583 PTGER2 Regulation of Gene_expression of TNFRSF11B 1 0.04 0.1 0
157 INT258008 PTGER2 Negative_regulation of Prkaca 1 0.02 0 0
158 INT298581 PTGER2 Regulation of Gene_expression of CSF1 1 0.06 0 0
159 INT34765 Binding of PTGER2 and REN 1 0.16 0.24 0
160 INT34766 Binding of PTGER2 and PTGIR 1 0.14 0.24 0
161 INT229040 IL32 Regulation of Gene_expression of PTGER2 1 0.01 0 0
162 INT196349 PLAT Positive_regulation of Gene_expression of PTGER2 1 0.00 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5732. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5732. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4
2 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27
3 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26
4 INT1764 Negative_regulation of Gene_expression of PTGER2 81 0.34 34.74 19.45
5 INT35487 Localization of PTGER2 103 0.46 51.24 17.45
6 INT1762 Negative_regulation of PTGER2 64 0.43 28.21 11.27
7 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95
8 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75
9 INT58393 Positive_regulation of Localization of PTGER2 37 0.25 16.8 6
10 INT58390 Negative_regulation of Localization of PTGER2 25 0.21 14.4 4.25
11 INT25122 Binding of PTGER2 31 0.31 13.83 3.12
12 INT58392 Regulation of Localization of PTGER2 10 0.25 5.18 2.19
13 INT34234 Positive_regulation of Positive_regulation of PTGER2 8 0.28 3.69 1.04
14 INT224740 Protein_catabolism of PTGER2 2 0.58 2.46 0.79
15 INT193261 Positive_regulation of Regulation of PTGER2 3 0.28 2.14 0.76
16 INT88124 Regulation of Positive_regulation of PTGER2 4 0.17 2 0.63
17 INT224739 Negative_regulation of Positive_regulation of PTGER2 3 0.18 1.7 0.55
18 INT92592 Transcription of PTGER2 6 0.32 4.52 0.47
19 INT176628 Positive_regulation of Binding of PTGER2 3 0.07 0.46 0.35
20 INT58394 Positive_regulation of Negative_regulation of PTGER2 1 0.01 0 0.32
21 INT196684 Regulation of Negative_regulation of PTGER2 1 0.02 0.24 0.31
22 INT224738 Negative_regulation of Protein_catabolism of PTGER2 2 0.29 1.72 0.3
23 INT310798 Regulation of Regulation of PTGER2 1 0.01 0.48 0.27
24 INT252191 Phosphorylation of PTGER2 3 0.30 0.06 0
25 INT203618 Negative_regulation of Binding of PTGER2 2 0.04 0.8 0
26 INT226278 Negative_regulation of Regulation of PTGER2 1 0.03 0 0
27 INT258000 Negative_regulation of Phosphorylation of PTGER2 1 0.16 0.06 0
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