G:5742

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Official Symbol PTGS1
Aliases COX1, COX3, PHS1, PCOX1, PGHS1, PTGHS, PGG/HS, PGHS-1
EntrezGene 5742
UniProt Coming Soon
Unique Molecular Interactions 25
Total Molecular Interactions 38
Total Single Events 1143
Unique Interaction Partners 19

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PTGS1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PTGS1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PTGS1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
3 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
4 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54
5 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5
6 INT167045 TRPA1 Regulation of PTGS1 1 0.19 0.1 0.35
7 INT5388 PTGS1 Negative_regulation of APRT 1 0.21 0.4 0.34
8 INT68557 ZNF697 Negative_regulation of PTGS1 1 0.02 0.59 0.33
9 INT64859 Negative_regulation of PTGS1 Negative_regulation of PTGS2 1 0.07 0.05 0.31
10 INT213062 PTGS1 Regulation of Gene_expression of MMP9 1 0.04 0.25 0.3
11 INT156082 Binding of PTGS1 and AKR1C3 1 0.01 0.31 0.3
12 INT65539 PTGS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.06 0.18 0.3
13 INT62207 Binding of PTGS1 and PTGS2 3 0.06 0.07 0.29
14 INT74942 HGF Positive_regulation of PTGS1 1 0.11 0.25 0.29
15 INT65540 Gene_expression of PTGS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.05 0.17 0.29
16 INT122000 Negative_regulation of PTGS1 Positive_regulation of Gene_expression of TNF 1 0.23 0.11 0.28
17 INT107392 PTGS2 Positive_regulation of PTGS1 2 0.31 1.01 0.26
18 INT64860 PTGS1 Negative_regulation of PTGS2 1 0.07 0 0.26
19 INT38711 CYSLTR1 Positive_regulation of Gene_expression of PTGS1 1 0.08 0.14 0.25
20 INT69317 PTGS2 Positive_regulation of Gene_expression of PTGS1 1 0.42 0.09 0.16
21 INT63453 Positive_regulation of PTGS1 Positive_regulation of Gene_expression of PLEKHM1 1 0.05 0.09 0.16
22 INT50500 Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
23 INT134405 Binding of PTGS1 and HPGDS 1 0.01 0.33 0.14
24 INT50498 Edn1 Regulation of Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
25 INT46268 MAPKAP1 Regulation of PTGS1 1 0.13 0 0.13
26 INT158506 COX5A Negative_regulation of PTGS1 1 0.06 0.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5742. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5742. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
2 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
3 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
4 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
5 INT9197 Binding of PTGS1 44 0.48 18.48 16.26
6 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27
7 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9
8 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23
9 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87
10 INT50491 Regulation of Gene_expression of PTGS1 17 0.47 6 5.4
11 INT39256 Localization of PTGS1 17 0.74 6.62 5.1
12 INT54823 Phosphorylation of PTGS1 4 0.51 1.61 2.14
13 INT32557 Negative_regulation of Negative_regulation of PTGS1 8 0.43 3.44 2.1
14 INT64915 Regulation of Negative_regulation of PTGS1 4 0.20 1.81 1.76
15 INT59077 Transcription of PTGS1 11 0.43 2.37 1.65
16 INT73260 Regulation of Positive_regulation of PTGS1 3 0.26 2.65 1.37
17 INT130198 Negative_regulation of Binding of PTGS1 3 0.34 2.6 1.16
18 INT78353 Positive_regulation of Positive_regulation of PTGS1 4 0.27 0.95 1.06
19 INT100142 Negative_regulation of Localization of PTGS1 2 0.35 1.71 0.91
20 INT69553 Negative_regulation of Regulation of PTGS1 1 0.16 0.78 0.91
21 INT80142 Positive_regulation of Localization of PTGS1 4 0.21 1.52 0.87
22 INT130782 Positive_regulation of Transcription of PTGS1 1 0.02 0.19 0.25
23 INT59081 Regulation of Transcription of PTGS1 1 0.11 0.16 0.21
24 INT62468 Protein_catabolism of PTGS1 2 0.18 0.14 0.15
25 INT185690 Regulation of Phosphorylation of PTGS1 1 0.10 0.07 0.15
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