G:5747

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Official Symbol PTK2
Aliases FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
EntrezGene 5747
UniProt Coming Soon
Unique Molecular Interactions 33
Total Molecular Interactions 47
Total Single Events 401
Unique Interaction Partners 22

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PTK2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PTK2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PTK2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
2 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
3 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
4 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
5 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
6 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
7 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
8 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
9 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
10 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
11 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
12 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
13 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
14 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
15 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 0.09 0.74 0.09
16 INT355582 VEGFA Regulation of Positive_regulation of PTK2 1 0.05 1.46 0.08
17 INT346280 Binding of COL5A2 and PTK2 1 0.01 0.1 0.05
18 INT292464 Binding of PTK2 and MMRN1 1 0.03 0.26 0
19 INT292505 PTK2 Regulation of Birc5 1 0.29 0.76 0
20 INT292444 BAD Positive_regulation of Phosphorylation of PTK2 1 0.13 0.9 0
21 INT292463 LAMB2 Positive_regulation of Phosphorylation of PTK2 1 0.01 0.7 0
22 INT292497 Mlph Positive_regulation of Phosphorylation of PTK2 1 0.05 7.24 0
23 INT292498 Mlph Regulation of Phosphorylation of PTK2 1 0.02 0.33 0
24 INT292452 Gene_expression of PTK2 Negative_regulation of Positive_regulation of AKT1 1 0.14 0.6 0
25 INT292453 PTK2 Regulation of Gene_expression of GEM 1 0.16 0.42 0
26 INT283863 Binding of MAPK1 and PTK2 1 0.12 0.97 0
27 INT292495 Mlph Regulation of Gene_expression of PTK2 1 0.03 0.21 0
28 INT292461 PTK2 Regulation of BCL2 1 0.02 0.76 0
29 INT292451 PTK2 Regulation of BAX 1 0.02 0.76 0
30 INT292448 Positive_regulation of PTK2 Positive_regulation of Phosphorylation of AKT1 1 0.15 0.28 0
31 INT292457 PTK2 Regulation of BAD 1 0.03 0.76 0
32 INT292506 Mlph Regulation of PTK2 1 0.01 0.21 0
33 INT292460 GEM Positive_regulation of Phosphorylation of PTK2 1 0.20 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5747. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5747. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
2 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
3 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
4 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
5 INT87346 Binding of PTK2 6 0.37 4.03 1.18
6 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
7 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
8 INT87341 Regulation of Gene_expression of PTK2 2 0.62 8.34 0.77
9 INT119080 Negative_regulation of PTK2 15 0.56 8.88 0.23
10 INT87338 Regulation of PTK2 10 0.62 4.75 0.21
11 INT292483 Negative_regulation of Positive_regulation of PTK2 2 0.41 3.51 0.18
12 INT147730 Regulation of Positive_regulation of PTK2 1 0.35 0.33 0.15
13 INT147735 Regulation of Binding of PTK2 1 0.35 0.23 0.08
14 INT144400 Positive_regulation of Gene_expression of PTK2 33 0.70 21.24 0.06
15 INT329775 Regulation of Regulation of PTK2 1 0.11 0.49 0.05
16 INT292474 Negative_regulation of Gene_expression of PTK2 8 0.41 5.17 0
17 INT262779 Localization of PTK2 3 0.71 2.75 0
18 INT292478 Negative_regulation of Negative_regulation of PTK2 1 0.41 0.97 0
19 INT329769 Positive_regulation of Localization of PTK2 1 0.17 1.42 0
20 INT292481 Negative_regulation of Localization of PTK2 1 0.41 0.07 0
21 INT329766 Positive_regulation of Positive_regulation of PTK2 1 0.11 0.51 0
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