G:5777

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Official Symbol PTPN6
Aliases HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1
EntrezGene 5777
UniProt Coming Soon
Unique Molecular Interactions 6
Total Molecular Interactions 6
Total Single Events 15
Unique Interaction Partners 5

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PTPN6. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PTPN6. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PTPN6. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT338901 Binding of PECAM1 and PTPN6 1 0.03 0.18 0.1
2 INT276386 Gtf3a Regulation of PTPN6 1 0.00 0.86 0.04
3 INT276392 Timp1 Regulation of PTPN6 1 0.02 0.87 0.04
4 INT322546 Negative_regulation of PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
5 INT194924 CD22 Positive_regulation of PTPN6 1 0.05 0.08 0
6 INT322545 PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
7 INT322487 PTPN6 Positive_regulation of Binding of CDK2 and CCNE2 1 0.00 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5777. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5777. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT321429 Positive_regulation of Gene_expression of PTPN6 1 0.03 1.78 0.41
2 INT252757 Negative_regulation of PTPN6 4 0.10 0.74 0.25
3 INT321425 Gene_expression of PTPN6 1 0.03 0.89 0.2
4 INT252729 Phosphorylation of PTPN6 2 0.03 0.67 0.08
5 INT194938 Regulation of PTPN6 2 0.29 0.48 0.08
6 INT276339 Localization of PTPN6 1 0.10 1.31 0.08
7 INT194944 Positive_regulation of PTPN6 1 0.06 0.46 0
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