G:5781

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Official Symbol PTPN11
Aliases CFC, NS1, SHP2, BPTP3, PTP2C, PTP-1D, SH-PTP2, SH-PTP3, MGC14433
EntrezGene 5781
UniProt Coming Soon
Unique Molecular Interactions 4
Total Molecular Interactions 6
Total Single Events 91
Unique Interaction Partners 4

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PTPN11. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PTPN11. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PTPN11. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT338898 Binding of PECAM1 and PTPN11 1 0.04 0.38 0.19
2 INT285580 Binding of PTPN11 and S100A8 1 0.05 0.2 0
3 INT279534 Binding of CFH and PTPN11 1 0.02 2.54 0
4 INT241300 Binding of IGHG3 and PTPN11 1 0.01 1.47 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5781. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5781. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT119827 Gene_expression of PTPN11 31 0.75 24.21 1.22
2 INT119836 Positive_regulation of Gene_expression of PTPN11 5 0.67 3.44 0.69
3 INT119826 Positive_regulation of PTPN11 2 0.45 2.67 0.43
4 INT241304 Regulation of Transcription of PTPN11 3 0.43 4.49 0.41
5 INT241302 Transcription of PTPN11 3 0.67 2.81 0.2
6 INT241305 Binding of PTPN11 9 0.46 6.08 0.1
7 INT267568 Negative_regulation of PTPN11 7 0.28 0.36 0.1
8 INT331322 Protein_catabolism of PTPN11 1 0.06 0.96 0.08
9 INT241303 Localization of PTPN11 8 0.77 10.23 0.06
10 INT326329 Regulation of Localization of PTPN11 1 0.20 0.74 0.06
11 INT285583 Regulation of PTPN11 3 0.44 1.17 0
12 INT332190 Regulation of Regulation of PTPN11 1 0.13 0.34 0
13 INT241301 Positive_regulation of Localization of PTPN11 1 0.45 2.78 0
14 INT285584 Positive_regulation of Binding of PTPN11 1 0.06 0 0
15 INT347597 Negative_regulation of Gene_expression of PTPN11 1 0.42 0.44 0
16 INT306211 Phosphorylation of PTPN11 1 0.79 1.13 0
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