G:5879

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Official Symbol RAC1
Aliases Rac-1, TC-25, p21-Rac1, MGC111543
EntrezGene 5879
UniProt Coming Soon
Unique Molecular Interactions 29
Total Molecular Interactions 32
Total Single Events 125
Unique Interaction Partners 18

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to RAC1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to RAC1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to RAC1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
2 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32
3 INT118848 GNA14 Positive_regulation of RAC1 1 0.01 0.14 0.26
4 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
5 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
6 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09
7 INT348167 Thbs1 Positive_regulation of RAC1 1 0.04 0.71 0.08
8 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05
9 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04
10 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04
11 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04
12 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03
13 INT194707 RAC1 Positive_regulation of PAK1 1 0.01 0 0.03
14 INT194738 Binding of PAK1 and RAC1 1 0.01 0 0.03
15 INT254511 RAC1 Positive_regulation of Positive_regulation of CYBB 1 0.14 0.39 0.03
16 INT225898 Positive_regulation of RAC1 Positive_regulation of PAK1 1 0.01 0.08 0
17 INT295710 PTGER2 Regulation of Positive_regulation of RAC1 1 0.01 1.62 0
18 INT295701 Positive_regulation of Binding of RAC1 and Racgap1 1 0.28 0.16 0
19 INT235011 Ctnnd1 Positive_regulation of RAC1 1 0.00 0.07 0
20 INT306269 Binding of MAPK8 and RAC1 1 0.25 0 0
21 INT101591 Binding of RAC1 and RAC3 1 0.13 0.52 0
22 INT225908 Binding of RAC1 and IQGAP1 1 0.00 0.09 0
23 INT225890 Binding of RAC1 and STAT3 1 0.01 0 0
24 INT295700 Binding of RAC1 and Racgap1 1 0.21 0.16 0
25 INT206077 RAC1 Positive_regulation of Phosphorylation of STAT3 1 0.07 0.35 0
26 INT194695 RAC1 Positive_regulation of PAK4 1 0.00 0 0
27 INT348534 ELMO1 Positive_regulation of RAC1 1 0.02 0.7 0
28 INT225891 DOCK1 Positive_regulation of RAC1 1 0.01 0 0
29 INT225899 Binding of DOCK1 and RAC1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5879. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5879. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
2 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
3 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
4 INT70987 Binding of RAC1 14 0.37 12.14 2.13
5 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4
6 INT175904 Localization of RAC1 7 0.41 5.05 0.86
7 INT111943 Negative_regulation of Positive_regulation of RAC1 2 0.46 1.33 0.86
8 INT111945 Protein_catabolism of RAC1 1 0.31 0.67 0.79
9 INT147734 Phosphorylation of RAC1 3 0.64 1.33 0.58
10 INT127736 Regulation of Gene_expression of RAC1 2 0.27 2 0.53
11 INT164267 Negative_regulation of Phosphorylation of RAC1 1 0.33 0.96 0.46
12 INT164266 Positive_regulation of Phosphorylation of RAC1 1 0.39 0.95 0.45
13 INT282160 Regulation of Binding of RAC1 1 0.18 0.45 0.13
14 INT176593 Positive_regulation of Gene_expression of RAC1 2 0.17 0.97 0.08
15 INT159858 Negative_regulation of Negative_regulation of RAC1 1 0.40 0.17 0.07
16 INT254550 Negative_regulation of Gene_expression of RAC1 1 0.13 0.63 0.04
17 INT254537 Negative_regulation of Binding of RAC1 1 0.13 0.64 0.04
18 INT206165 Positive_regulation of Localization of RAC1 1 0.16 0.07 0.03
19 INT257362 Negative_regulation of Localization of RAC1 1 0.24 0.58 0
20 INT295687 Positive_regulation of Binding of RAC1 1 0.25 0 0
21 INT295678 Regulation of Positive_regulation of RAC1 1 0.23 1.55 0
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