G:596

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Official Symbol BCL2
Aliases Bcl-2, PPP1R50
EntrezGene 596
UniProt Coming Soon
Unique Molecular Interactions 52
Total Molecular Interactions 70
Total Single Events 899
Unique Interaction Partners 41

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to BCL2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to BCL2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to BCL2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
2 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
3 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
4 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
5 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
6 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
7 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
8 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
9 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
10 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
11 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
12 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
13 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
14 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
15 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
16 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
17 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
18 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
19 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
20 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
21 INT265878 IGF1 Negative_regulation of Binding of BCL2 and BCL2L11 1 0.03 1.03 0.09
22 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
23 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
24 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
25 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
26 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
27 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03
28 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
29 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0
30 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0
31 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0
32 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0
33 INT197999 Binding of BCL2 and MCL1 Negative_regulation of C12orf65 1 0.00 1.21 0
34 INT321406 VEGFA Regulation of BCL2 1 0.01 0.75 0
35 INT292503 Mlph Regulation of Gene_expression of BCL2 1 0.00 0.4 0
36 INT348531 Binding of BCL2 and BECN1 1 0.06 0.43 0
37 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0
38 INT315060 PAR4 Regulation of BCL2 1 0.53 0.48 0
39 INT327972 Negative_regulation of BCL2 Positive_regulation of BAX 1 0.22 0.82 0
40 INT268516 Gene_expression of MIR16-2 Positive_regulation of Gene_expression of BCL2 1 0.00 1.15 0
41 INT335953 Binding of BCL2 and Bad 1 0.14 0.37 0
42 INT198021 Binding of BCL2 and MCL1 1 0.17 2.88 0
43 INT292458 Negative_regulation of Binding of BAD and BCL2 1 0.01 0.81 0
44 INT327977 TNFRSF11A Regulation of BCL2 1 0.05 0.67 0
45 INT189673 BCL2 Positive_regulation of Transcription of TERT 1 0.09 0 0
46 INT201774 Binding of BCL2 and BCL2L1 1 0.00 0.37 0
47 INT292461 PTK2 Regulation of BCL2 1 0.02 0.76 0
48 INT217141 Binding of BCL2 and MIR15B 1 0.21 1.26 0
49 INT193965 Binding of BCL2 and Ps 1 0.05 0.59 0
50 INT327976 PNLIP Negative_regulation of Gene_expression of BCL2 1 0.29 0.53 0
51 INT217146 Binding of BCL2 and MIR16-2 1 0.12 1.25 0
52 INT327974 GOPC Regulation of Gene_expression of BCL2 1 0.13 0.6 0
53 INT201538 Binding of BCL2 and NPC1 1 0.17 1.41 0
54 INT185853 Binding of BCL2 and BIK 1 0.36 0.59 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 596. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 596. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
2 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
3 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
4 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
5 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
6 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
7 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
8 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
9 INT70021 Localization of BCL2 23 0.74 21.6 1.09
10 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
11 INT70019 Binding of BCL2 25 0.47 17.55 0.79
12 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
13 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
14 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
15 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
16 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
17 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
18 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
19 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
20 INT302229 Negative_regulation of Negative_regulation of BCL2 3 0.21 2.69 0.04
21 INT258045 Positive_regulation of Regulation of BCL2 2 0.36 1.78 0.03
22 INT310419 Negative_regulation of Localization of BCL2 3 0.41 2.51 0
23 INT185909 Regulation of Phosphorylation of BCL2 3 0.24 1.63 0
24 INT185887 Regulation of Binding of BCL2 2 0.24 2.22 0
25 INT183619 Negative_regulation of Regulation of BCL2 2 0.33 1.01 0
26 INT153083 Positive_regulation of Negative_regulation of BCL2 2 0.32 2.9 0
27 INT330962 Negative_regulation of Transcription of BCL2 1 0.10 1.21 0
28 INT356124 Positive_regulation of Transcription of BCL2 1 0.45 0.3 0
29 INT184508 Positive_regulation of Localization of BCL2 1 0.07 0.87 0
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