G:60628

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Official Symbol Cxcr4
Aliases MGC108696
EntrezGene 60628
UniProt Coming Soon
Unique Molecular Interactions 21
Total Molecular Interactions 57
Total Single Events 192
Unique Interaction Partners 13

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Cxcr4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Cxcr4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Cxcr4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
3 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97
4 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97
5 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
6 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
7 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
8 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
9 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52
10 INT275399 Binding of ERVW-1 and Cxcr4 1 0.00 1.73 0.46
11 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44
12 INT253996 Binding of Cxcr2 and Cxcr4 1 0.18 0.81 0.44
13 INT281154 ITIH4 Positive_regulation of Cxcr4 1 0.09 0.71 0.37
14 INT281123 Binding of Cd4 and Cxcr4 1 0.24 0.92 0.37
15 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37
16 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
17 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
18 INT281133 Binding of Ccl2 and Cxcr4 1 0.06 0.63 0.24
19 INT253991 Negative_regulation of Binding of Cxcl12 and Cxcr4 1 0.43 0.41 0.21
20 INT249968 Cxcr4 Positive_regulation of Cxcl12 1 0.17 0.55 0.08
21 INT253993 Positive_regulation of Binding of Cxcr4 and Mif 1 0.50 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 60628. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 60628. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14
2 INT149069 Positive_regulation of Cxcr4 24 0.68 12.21 9.54
3 INT253974 Binding of Cxcr4 22 0.47 12.26 5.95
4 INT96744 Positive_regulation of Gene_expression of Cxcr4 14 0.68 7.92 5.75
5 INT96740 Transcription of Cxcr4 6 0.68 2.96 3.12
6 INT248177 Localization of Cxcr4 17 0.79 4.87 2.82
7 INT149068 Regulation of Cxcr4 3 0.44 3.77 2.46
8 INT110231 Regulation of Gene_expression of Cxcr4 7 0.44 3.18 2.44
9 INT126060 Negative_regulation of Gene_expression of Cxcr4 9 0.42 3.14 1.99
10 INT149553 Negative_regulation of Transcription of Cxcr4 2 0.36 0.29 1.06
11 INT253976 Positive_regulation of Positive_regulation of Cxcr4 1 0.46 1.19 0.96
12 INT149552 Negative_regulation of Positive_regulation of Cxcr4 1 0.09 0 0.88
13 INT281150 Regulation of Binding of Cxcr4 1 0.38 0.86 0.46
14 INT253984 Phosphorylation of Cxcr4 2 0.80 0.65 0.43
15 INT281143 Positive_regulation of Phosphorylation of Cxcr4 1 0.42 0.49 0.36
16 INT253973 Positive_regulation of Binding of Cxcr4 1 0.49 0.83 0.24
17 INT253978 Negative_regulation of Cxcr4 2 0.42 0.61 0.18
18 INT253971 Protein_catabolism of Cxcr4 1 0.98 0.62 0.12
19 INT253985 Regulation of Localization of Cxcr4 1 0.44 0.26 0.06
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