G:6093

Official Symbol ROCK1 Aliases ROCK-I, PRO0435, MGC43611, P160ROCK, MGC131603 EntrezGene 6093 UniProt Coming Soon

Unique Molecular Interactions 11 Total Molecular Interactions 16 Total Single Events 60 Unique Interaction Partners 8

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to ROCK1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to ROCK1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to ROCK1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT193031	CHRM2 Positive_regulation of ROCK1	1	0.00	0.12	0.24
2	INT343547	ROCK1 Positive_regulation of Gene_expression of PTHLH	1	0.15	0.2	0.2
3	INT193080	ROCK1 Positive_regulation of Ppp1r14a	1	0.00	0.13	0.18
4	INT343542	ROCK1 Positive_regulation of Positive_regulation of PTHLH	1	0.21	0	0.12
5	INT269584	Binding of CFL1 and ROCK1	1	0.03	0.05	0.03
6	INT343546	Negative_regulation of ROCK1 Negative_regulation of Gene_expression of PTHLH	1	0.16	3.28	0.03
7	INT343545	Binding of GLI2 and ROCK1	1	0.07	0.65	0.03
8	INT343537	ROCK1 Regulation of Gene_expression of PTHLH	1	0.08	0.09	0.03
9	INT258209	ROCK1 Regulation of ARR3	1	0.00	0.2	0
10	INT258202	ROCK1 Positive_regulation of MYL2	1	0.14	0.2	0
11	INT261730	ROCK1 Positive_regulation of Positive_regulation of F2R	1	0.37	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 6093. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 6093. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT126534	Negative_regulation of ROCK1	18	0.49	14.32	1.13
2	INT185436	Gene_expression of ROCK1	5	0.52	6.85	0.29
3	INT258250	Positive_regulation of ROCK1	7	0.51	2.07	0.22
4	INT185443	Regulation of ROCK1	4	0.18	3.32	0.21
5	INT341887	Positive_regulation of Positive_regulation of ROCK1	1	0.01	0.12	0.05
6	INT343555	Regulation of Gene_expression of ROCK1	1	0.15	1.02	0.04
7	INT192237	Phosphorylation of ROCK1	2	0.19	0.39	0.03
8	INT343556	Positive_regulation of Gene_expression of ROCK1	1	0.23	1.05	0.03
9	INT269651	Positive_regulation of Phosphorylation of ROCK1	1	0.11	0.29	0
10	INT258237	Negative_regulation of Negative_regulation of ROCK1	1	0.32	0.16	0
11	INT269645	Negative_regulation of Positive_regulation of ROCK1	1	0.10	0	0