G:6347

Official Symbol CCL2 Aliases HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30, MGC9434 EntrezGene 6347 UniProt Coming Soon

Unique Molecular Interactions 84 Total Molecular Interactions 124 Total Single Events 1141 Unique Interaction Partners 49

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CCL2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CCL2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CCL2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT149492	PNOC Negative_regulation of Gene_expression of CCL2	1	0.15	0.68	3.17
2	INT124121	IL6 Positive_regulation of CCL2	1	0.26	1.84	2.25
3	INT124120	IL6 Regulation of CCL2	1	0.15	1.8	2.22
4	INT200455	OPRK1 Positive_regulation of Gene_expression of CCL2	1	0.19	0.07	1.21
5	INT124119	IL6 Regulation of IL6 Positive_regulation of CCL2	1	0.12	0.92	1.13
6	INT260810	Binding of CXCL10 and CCL2	1	0.10	1.37	1.12
7	INT135585	CSF2 Regulation of CCL2	1	0.13	2.51	0.95
8	INT287494	CRP Positive_regulation of Gene_expression of CCL2	2	0.30	2.33	0.83
9	INT149561	Tgfb1 Positive_regulation of Gene_expression of CCL2	1	0.00	0	0.83
10	INT149563	Tgfb1 Positive_regulation of CCL2	1	0.00	0	0.83
11	INT87489	CALCA Positive_regulation of Gene_expression of CCL2	1	0.43	0.14	0.81
12	INT149495	PNOC Negative_regulation of CCL2	1	0.11	0.16	0.77
13	INT258644	Binding of CCL2 and CCL5	1	0.36	1.6	0.74
14	INT258643	Positive_regulation of Binding of CCL2 and CCL5	1	0.49	1.61	0.74
15	INT120017	CCL2 Positive_regulation of CCL3	1	0.01	0.99	0.7
16	INT120020	VEGFA Positive_regulation of CCL2	1	0.00	1	0.7
17	INT120035	CCL2 Positive_regulation of Prap1	1	0.00	0.99	0.7
18	INT130717	Binding of OPRM1 and Positive_regulation of Localization of CCL2	1	0.00	0.72	0.68
19	INT116441	IL1B Positive_regulation of Gene_expression of CCL2	2	0.04	0.62	0.65
20	INT153750	Binding of CCL2 and Crp	1	0.02	1.8	0.65
21	INT153751	Regulation of Binding of CCL2 and Crp	1	0.03	1.8	0.65
22	INT174860	VEGFA Positive_regulation of Localization of CCL2	1	0.21	1.68	0.63
23	INT252772	ELANE Regulation of Gene_expression of CCL2	1	0.05	2.16	0.62
24	INT252826	ROS1 Regulation of Gene_expression of CCL2	1	0.20	2.17	0.62
25	INT176470	TNF Positive_regulation of Gene_expression of CCL2	1	0.15	0.62	0.58
26	INT147201	Binding of CCL2 and Hsp70-2os	1	0.00	0.76	0.57
27	INT295708	Binding of EGF and CCL2	1	0.01	0.79	0.49
28	INT217040	Negative_regulation of IRF6 Positive_regulation of CCL2	1	0.00	1.24	0.47
29	INT217039	IRF6 Positive_regulation of CCL2	1	0.00	1.24	0.47
30	INT112800	CASP1 Positive_regulation of Gene_expression of CCL2	1	0.04	0.48	0.43
31	INT345288	AGT Positive_regulation of Localization of CCL2	1	0.01	1.5	0.43
32	INT345291	AGT Positive_regulation of CCL2	1	0.01	1.39	0.43
33	INT163909	CCL2 Positive_regulation of Positive_regulation of Ccr2	1	0.05	0.19	0.36
34	INT163906	CCL2 Positive_regulation of CCR2	1	0.18	0.2	0.35
35	INT163908	CCL2 Positive_regulation of Ccr2	1	0.05	0.2	0.35
36	INT134888	Negative_regulation of TNFRSF11A Negative_regulation of Gene_expression of CCL2	1	0.24	0.38	0.33
37	INT171257	TNFSF12 Positive_regulation of CCL2	1	0.01	0.3	0.29
38	INT306107	Binding of CCL2 and Ccr2	1	0.06	0	0.28
39	INT294709	IRF6 Positive_regulation of Gene_expression of CCL2	1	0.08	0.14	0.28
40	INT252806	F2 Positive_regulation of Gene_expression of CCL2	1	0.01	0.8	0.27
41	INT306941	Tnfsf12 Positive_regulation of Gene_expression of CCL2	1	0.03	1.65	0.27
42	INT342458	CSF1 Positive_regulation of Gene_expression of CCL2	1	0.17	0.84	0.27
43	INT353448	BRCA1 Positive_regulation of CCL2	1	0.01	1.37	0.26
44	INT120896	Binding of CCL2 and Il6	1	0.08	1.2	0.26
45	INT252822	CCL2 Positive_regulation of Positive_regulation of FOS	1	0.04	0.75	0.25
46	INT342456	AGT Positive_regulation of Gene_expression of CCL2	1	0.07	0.63	0.25
47	INT252786	CCL2 Regulation of Positive_regulation of FOS	1	0.05	0.75	0.25
48	INT252777	ROS1 Positive_regulation of Gene_expression of CCL2	1	0.31	0.77	0.23
49	INT112796	IL4I1 Positive_regulation of Gene_expression of CCL2	1	0.07	0	0.23
50	INT112801	IL4I1 Positive_regulation of CCL2	1	0.03	0	0.23
51	INT112798	CASP1 Positive_regulation of CCL2	1	0.02	0.19	0.21
52	INT252814	ELANE Positive_regulation of Positive_regulation of CCL2	1	0.05	0.8	0.2
53	INT306108	CCL2 Positive_regulation of Positive_regulation of Mapk3	1	0.03	0.15	0.2
54	INT252782	ROS1 Positive_regulation of Positive_regulation of CCL2	1	0.22	0.8	0.2
55	INT116440	LY9 Negative_regulation of Gene_expression of CCL2	1	0.14	0.09	0.16
56	INT303941	CCL2 Positive_regulation of Protein_catabolism of GLI2	1	0.01	0	0.16
57	INT220318	Binding of CPB1 and CCL2	1	0.01	0.46	0.13
58	INT355590	VEGFA Positive_regulation of Gene_expression of CCL2	1	0.07	1.35	0.1
59	INT294453	KLK4 Negative_regulation of CCL2	1	0.00	0	0.1
60	INT213416	Binding of CCL2 and SET	1	0.11	0.17	0.1
61	INT355585	VEGFA Positive_regulation of Positive_regulation of CCL2	1	0.07	1.35	0.1
62	INT132804	Positive_regulation of IL4 Positive_regulation of CCL2	1	0.22	0.6	0.09
63	INT132794	Positive_regulation of IL13 Positive_regulation of CCL2	1	0.21	0.6	0.09
64	INT294711	CRP Regulation of CCL2	1	0.12	0	0.09
65	INT132815	Positive_regulation of TNF Positive_regulation of CCL2	1	0.21	0.6	0.09
66	INT132793	IL4 Positive_regulation of CCL2	1	0.22	0.73	0.08
67	INT132816	IL13 Positive_regulation of CCL2	1	0.21	0.73	0.08
68	INT116439	CD8B Negative_regulation of Gene_expression of CCL2	1	0.02	0	0.08
69	INT286899	Binding of IL6 and CCL2	1	0.03	0.92	0.08
70	INT132811	IL1B Positive_regulation of CCL2	1	0.15	0.6	0.08
71	INT132814	TNF Positive_regulation of CCL2	1	0.21	0.6	0.08
72	INT288027	VEGFA Regulation of CCL2	1	0.44	0.26	0.03
73	INT132799	IL4 Positive_regulation of Localization of CCL2	1	0.22	0.13	0
74	INT164895	IL33 Positive_regulation of Gene_expression of CCL2	1	0.16	0.05	0
75	INT103680	Serpinf1 Negative_regulation of Positive_regulation of CCL2	1	0.00	0.15	0
76	INT206082	IL6 Positive_regulation of Gene_expression of CCL2	1	0.07	0.3	0
77	INT132790	IL13 Positive_regulation of Localization of CCL2	1	0.21	0.13	0
78	INT83446	CD40LG Positive_regulation of Localization of CCL2	1	0.00	0.17	0
79	INT355638	OLR1 Positive_regulation of Localization of CCL2	1	0.02	1.42	0
80	INT132797	IL1B Positive_regulation of Localization of CCL2	1	0.48	0.12	0
81	INT132798	TNF Positive_regulation of Localization of CCL2	1	0.29	0.12	0
82	INT355642	OLR1 Positive_regulation of Gene_expression of CCL2	1	0.03	2.85	0
83	INT232514	RS1 Regulation of Gene_expression of CCL2	1	0.00	0.26	0
84	INT103678	Serpinf1 Negative_regulation of CCL2	1	0.00	0.28	0
85	INT103679	Serpinf1 Negative_regulation of Gene_expression of CCL2	1	0.00	0.15	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 6347. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 6347. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT55879	Gene_expression of CCL2	421	0.78	240.74	166.02
2	INT67981	Positive_regulation of CCL2	165	0.70	136.84	61.85
3	INT81498	Positive_regulation of Gene_expression of CCL2	107	0.70	53.89	45.22
4	INT65698	Localization of CCL2	118	0.81	77.54	32.69
5	INT66857	Regulation of CCL2	39	0.53	28.55	18.35
6	INT55880	Negative_regulation of Gene_expression of CCL2	49	0.59	22.37	18.09
7	INT55878	Regulation of Gene_expression of CCL2	34	0.62	15.71	17.97
8	INT96850	Negative_regulation of CCL2	42	0.59	24.89	12.55
9	INT83450	Positive_regulation of Localization of CCL2	28	0.70	22.14	9.83
10	INT81493	Transcription of CCL2	20	0.65	13.63	6.78
11	INT120895	Binding of CCL2	22	0.37	15.86	6.55
12	INT96851	Negative_regulation of Localization of CCL2	14	0.53	5.98	4.57
13	INT113906	Regulation of Positive_regulation of CCL2	4	0.27	3.2	2.17
14	INT113907	Regulation of Localization of CCL2	5	0.62	2.46	2.05
15	INT100490	Negative_regulation of Positive_regulation of CCL2	6	0.23	1.48	1.96
16	INT67980	Positive_regulation of Positive_regulation of CCL2	7	0.49	5.89	1.85
17	INT81497	Positive_regulation of Transcription of CCL2	4	0.63	2	1.25
18	INT117552	Regulation of Regulation of CCL2	1	0.13	0.57	0.8
19	INT120010	Negative_regulation of Transcription of CCL2	1	0.02	0.99	0.72
20	INT222998	Positive_regulation of Negative_regulation of CCL2	1	0.12	1.11	0.59
21	INT102776	Phosphorylation of CCL2	1	0.65	1.55	0.56
22	INT290397	Positive_regulation of Binding of CCL2	1	0.22	0.99	0.46
23	INT306938	Regulation of Transcription of CCL2	1	0.05	0.81	0.13
24	INT239550	Negative_regulation of Binding of CCL2	1	0.18	0	0.13
25	INT152022	Regulation of Negative_regulation of CCL2	1	0.14	0	0