G:6387

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Official Symbol CXCL12
Aliases IRH, PBSF, SDF1, TLSF, SDF1A, SDF1B, TPAR1, SCYB12
EntrezGene 6387
UniProt Coming Soon
Unique Molecular Interactions 19
Total Molecular Interactions 47
Total Single Events 155
Unique Interaction Partners 17

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CXCL12. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CXCL12. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CXCL12. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
2 INT182208 Binding of CXCR2 and CXCL12 1 0.29 1.26 0.95
3 INT182198 Binding of CXCR5 and CXCL12 1 0.33 1.25 0.94
4 INT182209 Binding of CXCL12 and CXCL13 1 0.30 1.24 0.93
5 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66
6 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
7 INT190290 Binding of CXCL12 and VIPR1 1 0.06 0 0.33
8 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22
9 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
10 INT291358 Binding of CXCL12 and CXCR7 1 0.20 0.11 0.09
11 INT291355 CXCL12 Positive_regulation of Gene_expression of HGF 1 0.06 1.53 0.06
12 INT345307 CXCL12 Positive_regulation of Gene_expression of MMP15 1 0.00 2.5 0.05
13 INT224310 EPAS1 Positive_regulation of CXCL12 1 0.02 0.63 0.05
14 INT291356 CXCL12 Positive_regulation of AKT1 1 0.04 1.28 0.03
15 INT121650 Negative_regulation of Binding of CXCL12 and CXCR4 2 0.47 1.61 0
16 INT245071 Binding of CXCL12 and KDELR1 1 0.04 1.49 0
17 INT121652 Binding of CCR5 and CXCL12 1 0.33 0.2 0
18 INT121649 Binding of CD4 and CXCL12 1 0.29 0.2 0
19 INT245077 Binding of ESR1 and CXCL12 1 0.06 1.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 6387. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 6387. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79
2 INT121661 Binding of CXCL12 25 0.37 11.27 3.82
3 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48
4 INT121659 Positive_regulation of CXCL12 8 0.53 9.17 2.36
5 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36
6 INT113110 Negative_regulation of CXCL12 8 0.43 6.01 1.63
7 INT130647 Regulation of Gene_expression of CXCL12 6 0.39 5.01 1.38
8 INT245089 Localization of CXCL12 8 0.65 10.17 1.28
9 INT291371 Positive_regulation of Localization of CXCL12 2 0.35 2.8 0.65
10 INT291367 Negative_regulation of Gene_expression of CXCL12 3 0.32 4.15 0.47
11 INT245087 Transcription of CXCL12 2 0.46 2.04 0.2
12 INT312713 Protein_catabolism of CXCL12 1 0.37 0.45 0.17
13 INT291363 Positive_regulation of Binding of CXCL12 1 0.38 0.36 0.03
14 INT245083 Regulation of Positive_regulation of CXCL12 1 0.39 1.6 0
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