G:63873

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Official Symbol Trpv4
Aliases Trp12, VRL-2, VROAC, OTRPC4, VR-OAC, MGC150050, 0610033B08Rik
EntrezGene 63873
UniProt Coming Soon
Unique Molecular Interactions 32
Total Molecular Interactions 51
Total Single Events 358
Unique Interaction Partners 18

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Trpv4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Trpv4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Trpv4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
2 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
3 INT159688 Trpv4 Negative_regulation of Trpv3 1 0.31 0.41 0.76
4 INT159689 Trpv4 Negative_regulation of Trpv1 1 0.36 0.41 0.76
5 INT159687 Trpv4 Negative_regulation of Trpv2 1 0.32 0.41 0.76
6 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
7 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5
8 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5
9 INT137672 Baa1 Positive_regulation of Trpv4 1 0.17 0 0.11
10 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07
11 INT196124 Trpm5 Negative_regulation of Trpv4 1 0.13 0.08 0.06
12 INT196134 Gopc Negative_regulation of Trpv4 1 0.07 0.08 0.06
13 INT196126 Gopc Negative_regulation of Gene_expression of Trpv4 1 0.15 0.08 0.06
14 INT196131 Trpm7 Negative_regulation of Trpv4 1 0.14 0.08 0.06
15 INT196130 Trpm5 Negative_regulation of Gene_expression of Trpv4 1 0.30 0.08 0.06
16 INT196129 Trpm7 Negative_regulation of Gene_expression of Trpv4 1 0.32 0.08 0.06
17 INT333034 Trpv4 Positive_regulation of Localization of Car2 1 0.06 0 0.05
18 INT333032 Binding of Trpv4 and Gopc 1 0.05 0 0.04
19 INT241253 Gene_expression of Trpv4 Positive_regulation of Gene_expression of Pkd2 1 0.52 0.29 0.03
20 INT333037 Binding of Agt and Trpv4 1 0.09 0 0.03
21 INT333035 Positive_regulation of Binding of Agt and Trpv4 1 0.11 0 0
22 INT333030 Binding of Itch and Trpv4 1 0.14 0 0
23 INT333046 Binding of Trpv4 and ITCH 1 0.39 0 0
24 INT333036 Trpv4 Positive_regulation of Gene_expression of Agt 1 0.12 0 0
25 INT261833 Binding of Add3 and Trpv4 1 0.00 0.12 0
26 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0
27 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0
28 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0
29 INT333044 Positive_regulation of Binding of AGTR1 and Trpv4 1 0.48 0 0
30 INT261844 Lyn Positive_regulation of Lyn Regulation of Trpv4 1 0.01 0.19 0
31 INT333038 Agt Positive_regulation of Positive_regulation of Trpv4 1 0.12 0 0
32 INT333043 Binding of AGTR1 and Trpv4 1 0.50 0 0
33 INT261837 Binding of Aqp5 and Trpv4 1 0.05 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 63873. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 63873. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11
2 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3
3 INT124881 Binding of Trpv4 35 0.47 7.71 6.24
4 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86
5 INT109821 Negative_regulation of Trpv4 19 0.55 6.86 3.98
6 INT168744 Negative_regulation of Regulation of Trpv4 1 0.42 3.26 2.87
7 INT115852 Transcription of Trpv4 9 0.71 2.23 2.65
8 INT109822 Negative_regulation of Gene_expression of Trpv4 8 0.55 1.98 2.53
9 INT115199 Localization of Trpv4 12 0.79 3.65 2.5
10 INT137670 Positive_regulation of Gene_expression of Trpv4 12 0.68 3.42 1.77
11 INT261816 Positive_regulation of Localization of Trpv4 2 0.47 1.16 1.07
12 INT263225 Positive_regulation of Positive_regulation of Trpv4 3 0.46 0.75 0.7
13 INT125188 Negative_regulation of Transcription of Trpv4 3 0.42 0.44 0.56
14 INT263224 Phosphorylation of Trpv4 2 0.76 0.73 0.49
15 INT137671 Negative_regulation of Positive_regulation of Trpv4 3 0.58 0.25 0.48
16 INT212307 Regulation of Gene_expression of Trpv4 8 0.44 2.85 0.39
17 INT333015 Regulation of Binding of Trpv4 1 0.42 0.43 0.13
18 INT333013 Positive_regulation of Protein_catabolism of Trpv4 1 0.43 0 0
19 INT333010 Positive_regulation of Binding of Trpv4 1 0.47 0 0
20 INT333022 Positive_regulation of Phosphorylation of Trpv4 1 0.47 0 0
21 INT333018 Positive_regulation of Negative_regulation of Trpv4 1 0.43 0 0
22 INT333016 Protein_catabolism of Trpv4 1 0.93 0 0
23 INT333026 Regulation of Localization of Trpv4 1 0.42 0 0
24 INT333027 Negative_regulation of Binding of Trpv4 1 0.40 0 0
25 INT333017 Negative_regulation of Localization of Trpv4 1 0.40 0 0
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