G:6490

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Official Symbol PMEL
Aliases P1, SI, SIL, ME20, P100, SILV, ME20M, gp100, ME20-M, PMEL17, D12S53E
EntrezGene 6490
UniProt Coming Soon
Unique Molecular Interactions 12
Total Molecular Interactions 14
Total Single Events 79
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PMEL. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PMEL. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PMEL. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227496 PTPN4 Regulation of PMEL 1 0.00 0.45 0.33
2 INT71642 Binding of HLA-A and PMEL 2 0.20 1.05 0.26
3 INT71639 Binding of MLANA and PMEL 1 0.27 0.36 0.26
4 INT120152 Binding of PMEL and SLC9A7 1 0.07 0 0.09
5 INT120153 Binding of PMEL and SLC9A3 1 0.07 0 0.09
6 INT140606 PMEL Negative_regulation of Gene_expression of ATF4 1 0.01 0.74 0.08
7 INT140609 PMEL Negative_regulation of Gene_expression of ATF6 1 0.01 0.74 0.08
8 INT140605 PMEL Negative_regulation of Transcription of ATF4 1 0.01 0.74 0.08
9 INT335240 Binding of CD8A and PMEL 1 0.28 0.81 0
10 INT140607 PMEL Positive_regulation of Gene_expression of DDIT3 1 0.01 0.75 0
11 INT335239 Binding of HLA-DOA and PMEL 1 0.04 0.68 0
12 INT335242 Binding of PMEL and CD160 1 0.36 0.85 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 6490. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 6490. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5789 Gene_expression of PMEL 23 0.75 13.18 2.67
2 INT11388 Positive_regulation of PMEL 11 0.67 5.9 2.09
3 INT99357 Positive_regulation of Localization of PMEL 1 0.67 0.51 1.52
4 INT69309 Positive_regulation of Gene_expression of PMEL 3 0.49 0.9 1.05
5 INT56148 Localization of PMEL 5 0.78 1.87 0.93
6 INT45093 Binding of PMEL 10 0.37 4.77 0.89
7 INT11387 Negative_regulation of PMEL 3 0.57 1.53 0.56
8 INT49022 Transcription of PMEL 1 0.46 0.41 0.28
9 INT111770 Regulation of PMEL 2 0.44 0.4 0.12
10 INT227247 Positive_regulation of Positive_regulation of PMEL 2 0.19 0.37 0.08
11 INT64844 Protein_catabolism of PMEL 1 0.75 0.22 0.05
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