G:6532

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Official Symbol SLC6A4
Aliases HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR
EntrezGene 6532
UniProt Coming Soon
Unique Molecular Interactions 11
Total Molecular Interactions 14
Total Single Events 317
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to SLC6A4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to SLC6A4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to SLC6A4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
2 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
3 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
4 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
5 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
6 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
7 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
8 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
9 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
10 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
11 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 6532. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 6532. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
2 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
3 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
4 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
5 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
6 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
7 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
8 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
9 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
10 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
11 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
12 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
13 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
14 INT147809 Localization of SLC6A4 5 0.71 1.69 0.74
15 INT129524 Regulation of Regulation of SLC6A4 1 0.26 0.16 0.5
16 INT352021 Negative_regulation of Negative_regulation of SLC6A4 1 0.08 0.2 0.5
17 INT150168 Negative_regulation of Transcription of SLC6A4 1 0.42 0.16 0.47
18 INT150167 Positive_regulation of Transcription of SLC6A4 1 0.45 0.16 0.46
19 INT140668 Positive_regulation of Negative_regulation of SLC6A4 1 0.56 0.23 0.36
20 INT124930 Positive_regulation of Binding of SLC6A4 1 0.40 0.06 0.33
21 INT341784 Positive_regulation of Phosphorylation of SLC6A4 1 0.29 0.07 0.26
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