G:6714

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Official Symbol SRC
Aliases ASV, SRC1, c-SRC, p60-Src
EntrezGene 6714
UniProt Coming Soon
Unique Molecular Interactions 46
Total Molecular Interactions 51
Total Single Events 187
Unique Interaction Partners 32

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to SRC. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to SRC. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to SRC. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
2 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
3 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
4 INT299263 PTPN3 Negative_regulation of VEGFA Positive_regulation of SRC 1 0.03 0.35 0.57
5 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
6 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
7 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
8 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
9 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
10 INT118853 Negative_regulation of SRC Negative_regulation of Positive_regulation of STAT3 1 0.41 0.08 0.28
11 INT118855 Binding of SRC and GNA14 1 0.01 0.13 0.27
12 INT100680 IL4 Positive_regulation of SRC 1 0.42 0.66 0.26
13 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
14 INT118858 PRKCA Regulation of Phosphorylation of SRC 1 0.10 0.15 0.24
15 INT118850 GNA14 Positive_regulation of Phosphorylation of SRC 1 0.02 0.15 0.23
16 INT292087 SRC Regulation of IL8 1 0.02 1.43 0.11
17 INT299291 Negative_regulation of PTPN3 Positive_regulation of Phosphorylation of SRC 1 0.07 0.12 0.07
18 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05
19 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05
20 INT238113 SRC Regulation of Phosphorylation of STAT3 1 0.46 0 0.04
21 INT302126 PTGER2 Positive_regulation of SRC 1 0.11 1.08 0.03
22 INT213905 ESR1 Positive_regulation of SRC 1 0.14 0.31 0.03
23 INT338198 SRC Positive_regulation of STAT3 1 0.11 0.34 0
24 INT299303 SRC Regulation of Phosphorylation of VEGFA 1 0.12 0.05 0
25 INT285579 Binding of S100A8 and SRC 1 0.05 0.2 0
26 INT299305 VEGFA Positive_regulation of Positive_regulation of SRC 1 0.22 0 0
27 INT299300 SRC Positive_regulation of Phosphorylation of AKT1 1 0.24 0 0
28 INT279289 TXK Regulation of SRC 1 0.04 0.68 0
29 INT299296 SRC Regulation of RPTOR 1 0.32 0 0
30 INT114712 SRC Positive_regulation of Gene_expression of IGF1R 1 0.63 0.51 0
31 INT338189 SRC Positive_regulation of HGFAC 1 0.00 0.4 0
32 INT299285 SRC Regulation of Gene_expression of QPCT 1 0.03 0 0
33 INT302174 Positive_regulation of SRC Positive_regulation of Phosphorylation of STAT3 1 0.11 1.01 0
34 INT302142 PTGER3 Positive_regulation of SRC 1 0.09 1.07 0
35 INT299308 SRC Regulation of PI3 1 0.20 0 0
36 INT299298 SRC Negative_regulation of PI3 1 0.19 0 0
37 INT338178 Binding of CDCP1 and CDCP1 Positive_regulation of SRC 1 0.00 0.31 0
38 INT338195 Binding of SRC and FIBP 1 0.00 0.31 0
39 INT309906 Binding of EGF and SRC 1 0.11 0.64 0
40 INT114713 Binding of IGF1R and SRC 1 0.33 0.6 0
41 INT340928 Negative_regulation of SRC Negative_regulation of Positive_regulation of AKT1 1 0.00 0 0
42 INT299294 SRC Regulation of VEGFA 1 0.20 0 0
43 INT238120 SRC Positive_regulation of Positive_regulation of STAT3 1 0.71 0 0
44 INT238114 Binding of CSK and SRC 1 0.07 0 0
45 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
46 INT338196 Binding of SRC and CDCP1 1 0.00 0.31 0
47 INT198019 NPY6R Negative_regulation of Gene_expression of SRC 1 0.06 1.75 0
48 INT114711 SRC Positive_regulation of Gene_expression of INSRR 1 0.01 0.51 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 6714. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 6714. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
2 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
3 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08
4 INT98464 Positive_regulation of Positive_regulation of SRC 10 0.67 5.71 1.86
5 INT82609 Phosphorylation of SRC 17 0.80 6.45 1.7
6 INT114715 Binding of SRC 8 0.36 4.26 1.32
7 INT219950 Negative_regulation of Gene_expression of SRC 2 0.29 1.32 1.15
8 INT118004 Positive_regulation of Gene_expression of SRC 13 0.49 11.05 0.8
9 INT82608 Positive_regulation of Phosphorylation of SRC 3 0.49 1.28 0.48
10 INT138051 Negative_regulation of Positive_regulation of SRC 3 0.57 0.84 0.33
11 INT164162 Negative_regulation of Phosphorylation of SRC 3 0.29 2.12 0.21
12 INT235725 Regulation of SRC 7 0.44 4.71 0.19
13 INT299357 Localization of SRC 1 0.51 0 0.09
14 INT238187 Regulation of Positive_regulation of SRC 2 0.26 1.37 0.05
15 INT238193 Regulation of Gene_expression of SRC 1 0.44 0 0.03
16 INT238185 Regulation of Binding of SRC 1 0.44 0.06 0
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