G:672

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Official Symbol BRCA1
Aliases IRIS, PSCP, BRCAI, BRCC1, PNCA4, RNF53, BROVCA1, PPP1R53
EntrezGene 672
UniProt Coming Soon
Unique Molecular Interactions 13
Total Molecular Interactions 17
Total Single Events 106
Unique Interaction Partners 12

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to BRCA1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to BRCA1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to BRCA1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
2 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
3 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
4 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
5 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
6 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
7 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
8 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05
9 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
10 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
11 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0
12 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0
13 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 672. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 672. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
2 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
3 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
4 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
5 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
6 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34
7 INT221419 Regulation of BRCA1 5 0.35 6.18 0.31
8 INT221268 Localization of BRCA1 7 0.63 4.83 0.18
9 INT119061 Negative_regulation of Gene_expression of BRCA1 4 0.51 0.85 0.18
10 INT344009 Negative_regulation of Localization of BRCA1 1 0.30 0.18 0.03
11 INT259116 Transcription of BRCA1 3 0.44 3.77 0
12 INT119064 Regulation of Gene_expression of BRCA1 1 0.53 0.05 0
13 INT221271 Negative_regulation of Binding of BRCA1 1 0.28 0.93 0
14 INT334189 Regulation of Binding of BRCA1 1 0.13 0.8 0
15 INT234188 Positive_regulation of Localization of BRCA1 1 0.42 0.68 0
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