G:7076

From wiki-pain
Jump to: navigation, search
Official Symbol TIMP1
Aliases EPA, EPO, HCI, CLGI, TIMP, FLJ90373
EntrezGene 7076
UniProt Coming Soon
Unique Molecular Interactions 87
Total Molecular Interactions 109
Total Single Events 829
Unique Interaction Partners 56

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to TIMP1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to TIMP1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to TIMP1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
2 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
3 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74
4 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71
5 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
6 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
7 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
8 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56
9 INT173555 TIMP1 Negative_regulation of MMP7 1 0.01 0 0.56
10 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
11 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
12 INT173557 TIMP1 Negative_regulation of MMP3 1 0.02 0 0.56
13 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55
14 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55
15 INT285758 RETNLB Positive_regulation of Gene_expression of TIMP1 1 0.01 1.79 0.55
16 INT196522 Binding of MMP1 and TIMP1 1 0.39 0.29 0.53
17 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
18 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
19 INT277064 CRP Positive_regulation of Gene_expression of TIMP1 1 0.15 1.47 0.45
20 INT181995 TIMP1 Negative_regulation of Mmp9 1 0.01 1.38 0.4
21 INT198969 GAPDH Negative_regulation of TIMP1 1 0.47 0 0.35
22 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29
23 INT335307 SLC15A4 Regulation of TIMP1 1 0.01 0.69 0.29
24 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29
25 INT55682 IL1B Positive_regulation of TIMP1 2 0.46 0.17 0.28
26 INT218709 Mmp1a Negative_regulation of TIMP1 1 0.00 1.84 0.28
27 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28
28 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28
29 INT55683 IL1B Positive_regulation of Gene_expression of TIMP1 1 0.64 0.17 0.28
30 INT55681 IL1B Regulation of Gene_expression of TIMP1 1 0.56 0.18 0.28
31 INT275556 Il10 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28
32 INT275509 IL8 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28
33 INT172140 CSF2 Positive_regulation of Gene_expression of TIMP1 1 0.07 0.72 0.27
34 INT34231 PTGER2 Positive_regulation of Gene_expression of TIMP1 1 0.13 0.23 0.27
35 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
36 INT277066 MMP1 Positive_regulation of Gene_expression of TIMP1 1 0.16 0.76 0.24
37 INT227905 IL10 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.48 0.22
38 INT220192 PTGER2 Negative_regulation of Positive_regulation of TIMP1 1 0.04 0.99 0.22
39 INT205051 MMP3 Negative_regulation of TIMP1 1 0.36 3.02 0.2
40 INT336379 TIMP1 Negative_regulation of FADS1 1 0.01 0.52 0.2
41 INT21576 NT5C3 Negative_regulation of Gene_expression of TIMP1 1 0.03 0.25 0.2
42 INT214590 TIMP1 Regulation of ICAM1 1 0.10 0.29 0.19
43 INT21577 IL4I1 Positive_regulation of Gene_expression of TIMP1 1 0.11 0.24 0.19
44 INT335299 IRF6 Positive_regulation of TIMP1 1 0.03 0.21 0.19
45 INT181996 TNFRSF11B Positive_regulation of Gene_expression of TIMP1 1 0.00 0.67 0.18
46 INT181928 RLN1 Positive_regulation of TIMP1 1 0.00 0.1 0.17
47 INT97820 Serpine1 Negative_regulation of TIMP1 1 0.00 0.29 0.17
48 INT185808 SPP1 Positive_regulation of TIMP1 1 0.64 0.33 0.16
49 INT290444 S100A4 Regulation of TIMP1 1 0.00 1.3 0.14
50 INT281267 Binding of CRP and TIMP1 1 0.06 0.82 0.13
51 INT170991 FGF2 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.72 0.13
52 INT337676 Binding of TIMP1 and Scrib 1 0.01 1.24 0.13
53 INT185416 MUC1 Negative_regulation of TIMP1 1 0.18 0.84 0.13
54 INT185418 IGHG1 Negative_regulation of TIMP1 1 0.11 0.84 0.13
55 INT126882 Negative_regulation of TIMP1 Regulation of NA 1 0.28 0 0.12
56 INT213144 TIMP1 Negative_regulation of THBD 1 0.04 1.16 0.12
57 INT220197 PTGER2 Negative_regulation of TIMP1 1 0.03 0.23 0.12
58 INT181929 GOPC Regulation of Gene_expression of TIMP1 1 0.00 0 0.12
59 INT126883 TIMP1 Regulation of NA 1 0.17 0 0.12
60 INT245313 Negative_regulation of Binding of MMP2 and TIMP1 1 0.01 0.45 0.11
61 INT187112 Binding of TIMP2 and Positive_regulation of TIMP1 1 0.32 0.26 0.1
62 INT218713 Mmp1a Negative_regulation of Gene_expression of TIMP1 1 0.00 0.18 0.1
63 INT213145 DAK Positive_regulation of TIMP1 1 0.02 0.36 0.09
64 INT277053 Protein_catabolism of TIMP1 Positive_regulation of COL5A2 1 0.01 0.14 0.07
65 INT336383 TIMP1 Positive_regulation of Ppara 1 0.08 0.77 0.07
66 INT187104 Binding of IGHG3 and TIMP1 1 0.01 0.22 0.07
67 INT266655 TIMP1 Regulation of Gene_expression of MMP9 1 0.18 0.11 0.06
68 INT266662 TIMP1 Regulation of Gene_expression of GOPC 1 0.06 0.11 0.06
69 INT182259 EDN1 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.27 0.05
70 INT209155 MMP9 Negative_regulation of TIMP1 1 0.01 0.17 0.05
71 INT220189 Binding of COL2A1 and TIMP1 1 0.04 0.1 0.05
72 INT209156 MMP2 Negative_regulation of TIMP1 1 0.00 0.17 0.05
73 INT192263 LTC4S Positive_regulation of Gene_expression of TIMP1 1 0.00 0.28 0.04
74 INT180955 PLG Regulation of Positive_regulation of TIMP1 1 0.21 0.38 0.04
75 INT270330 Binding of HYAL1 and TIMP1 1 0.00 0.2 0.04
76 INT274715 TBL1XR1 Positive_regulation of TIMP1 1 0.00 0.26 0.04
77 INT335289 IRF6 Positive_regulation of Gene_expression of TIMP1 1 0.03 0.16 0.04
78 INT335312 SLC15A4 Negative_regulation of TIMP1 1 0.01 0.07 0
79 INT213148 TIMP1 Regulation of DAK 1 0.01 0.73 0
80 INT156682 ASAP1 Negative_regulation of Gene_expression of TIMP1 1 0.17 0.07 0
81 INT281259 Binding of INS and TIMP1 1 0.04 0.27 0
82 INT339581 Binding of TIMP1 and TIMP3 1 0.30 0.54 0
83 INT185817 SPP1 Positive_regulation of Gene_expression of TIMP1 1 0.64 0 0
84 INT213146 TIMP1 Regulation of HSD11B1 1 0.02 0.7 0
85 INT213143 DAK Regulation of TIMP1 1 0.01 0.73 0
86 INT185801 SPP1 Regulation of Gene_expression of TIMP1 1 0.25 0 0
87 INT266657 TIMP1 Regulation of Localization of MMP9 1 0.18 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 7076. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 7076. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29
2 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54
3 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86
4 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98
5 INT55687 Localization of TIMP1 47 0.74 30.24 12.31
6 INT36678 Binding of TIMP1 33 0.36 14.99 7.87
7 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94
8 INT34232 Regulation of TIMP1 37 0.61 18.76 6.05
9 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51
10 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77
11 INT55690 Positive_regulation of Localization of TIMP1 8 0.50 4.77 3.28
12 INT53131 Transcription of TIMP1 8 0.68 3.89 1.5
13 INT172176 Regulation of Regulation of TIMP1 1 0.20 2.33 0.97
14 INT110739 Negative_regulation of Negative_regulation of TIMP1 4 0.41 3.29 0.95
15 INT295679 Regulation of Localization of TIMP1 1 0.17 2.7 0.93
16 INT178987 Positive_regulation of Positive_regulation of TIMP1 5 0.20 2.81 0.83
17 INT34233 Regulation of Negative_regulation of TIMP1 3 0.27 0.48 0.77
18 INT51053 Negative_regulation of Positive_regulation of TIMP1 6 0.35 1.67 0.69
19 INT55689 Positive_regulation of Transcription of TIMP1 3 0.46 1.02 0.67
20 INT213154 Positive_regulation of Binding of TIMP1 2 0.41 1.33 0.55
21 INT173583 Negative_regulation of Binding of TIMP1 1 0.13 0 0.48
22 INT110738 Positive_regulation of Negative_regulation of TIMP1 4 0.44 0.44 0.45
23 INT150095 Regulation of Positive_regulation of TIMP1 2 0.44 0.76 0.41
24 INT156686 Negative_regulation of Localization of TIMP1 2 0.35 1.29 0.22
25 INT341658 Negative_regulation of Regulation of TIMP1 1 0.33 0.91 0.21
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox