G:7077

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Official Symbol TIMP2
Aliases CSC-21K
EntrezGene 7077
UniProt Coming Soon
Unique Molecular Interactions 28
Total Molecular Interactions 32
Total Single Events 116
Unique Interaction Partners 17

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to TIMP2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to TIMP2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to TIMP2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
2 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71
3 INT150795 ZNF398 Positive_regulation of Localization of TIMP2 1 0.06 0.51 0.53
4 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
5 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
6 INT150798 THBS3 Negative_regulation of TIMP2 1 0.18 0.49 0.52
7 INT196521 Binding of MMP2 and TIMP2 1 0.30 0.68 0.52
8 INT150783 ZNF398 Positive_regulation of THBS1 Negative_regulation of TIMP2 1 0.04 0.5 0.52
9 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
10 INT150799 ZNF398 Positive_regulation of TIMP2 1 0.09 0.49 0.51
11 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5
12 INT345306 Binding of MMP14 and TIMP2 1 0.04 0.21 0.48
13 INT345301 Binding of MMP14 and TIMP2 Positive_regulation of MMP2 1 0.02 0.21 0.48
14 INT187102 Negative_regulation of Binding of MMP9 and TIMP2 1 0.36 0.69 0.3
15 INT187106 Binding of MMP9 and TIMP2 1 0.30 0.69 0.3
16 INT187110 Binding of TIMP2 and GOPC 1 0.07 0.64 0.29
17 INT187105 TIMP2 Negative_regulation of Positive_regulation of MMP9 1 0.36 0.36 0.29
18 INT187107 Binding of IGHG3 and TIMP2 1 0.01 0.62 0.28
19 INT187117 Negative_regulation of TIMP2 Negative_regulation of MMP9 1 0.36 0.6 0.22
20 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
21 INT323884 BMI1 Regulation of Gene_expression of TIMP2 1 0.01 0.64 0.21
22 INT290443 Gene_expression of TIMP2 Negative_regulation of MMP2 1 0.06 1.56 0.13
23 INT203628 Cxcl1 Negative_regulation of TIMP2 1 0.01 0 0.1
24 INT203583 IL8 Negative_regulation of TIMP2 1 0.03 0 0.1
25 INT187112 Binding of TIMP2 and Positive_regulation of TIMP1 1 0.32 0.26 0.1
26 INT203590 Negative_regulation of IL6 Negative_regulation of TIMP2 1 0.07 0 0.1
27 INT203586 IL6 Negative_regulation of TIMP2 1 0.07 0 0.1
28 INT94426 CTS Positive_regulation of Gene_expression of TIMP2 1 0.04 0 0
29 INT94424 IL1B Negative_regulation of Negative_regulation of TIMP2 1 0.06 0 0
30 INT94425 IL1B Negative_regulation of Transcription of TIMP2 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 7077. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 7077. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93664 Gene_expression of TIMP2 33 0.67 36.67 7.14
2 INT94433 Negative_regulation of TIMP2 16 0.55 9.38 4.78
3 INT101912 Regulation of TIMP2 8 0.44 5.55 2
4 INT52508 Positive_regulation of TIMP2 7 0.43 8.1 1.96
5 INT187128 Binding of TIMP2 11 0.41 6.43 1.9
6 INT150809 Localization of TIMP2 7 0.65 2.6 1.43
7 INT187026 Positive_regulation of Gene_expression of TIMP2 3 0.47 2.05 0.96
8 INT101913 Regulation of Gene_expression of TIMP2 2 0.44 1.2 0.93
9 INT93665 Negative_regulation of Gene_expression of TIMP2 4 0.37 2.47 0.82
10 INT94429 Transcription of TIMP2 3 0.61 4.05 0.67
11 INT94430 Positive_regulation of Transcription of TIMP2 2 0.24 2.25 0.39
12 INT187136 Negative_regulation of Localization of TIMP2 1 0.37 0.69 0.3
13 INT187130 Positive_regulation of Negative_regulation of TIMP2 1 0.43 0.78 0.29
14 INT323894 Negative_regulation of Regulation of TIMP2 1 0.20 1.04 0.23
15 INT187124 Positive_regulation of Positive_regulation of TIMP2 1 0.40 0.22 0.11
16 INT323892 Regulation of Transcription of TIMP2 1 0.21 0.9 0.08
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