G:7097

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Official Symbol TLR2
Aliases TIL4, CD282
EntrezGene 7097
UniProt Coming Soon
Unique Molecular Interactions 50
Total Molecular Interactions 71
Total Single Events 498
Unique Interaction Partners 35

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to TLR2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to TLR2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to TLR2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
2 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
3 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
4 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
5 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
6 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44
7 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43
8 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41
9 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41
10 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41
11 INT306254 Binding of TLR2 and LY96 1 0.25 1.29 0.36
12 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35
13 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
14 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32
15 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32
16 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32
17 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
18 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
19 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31
20 INT193479 TLR2 Regulation of Binding of IRF6 1 0.04 0.75 0.28
21 INT230460 Binding of TLR2 and TLR6 2 0.07 1.9 0.25
22 INT175324 Hsp90b1 Positive_regulation of TLR2 1 0.00 0.65 0.23
23 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23
24 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23
25 INT231763 Binding of HSPD1 and TLR2 1 0.12 2 0.19
26 INT316124 TLR2 Positive_regulation of Gene_expression of HLA-DRA 1 0.14 0.34 0.16
27 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16
28 INT342520 HSP90B1 Positive_regulation of Gene_expression of TLR2 1 0.06 0.4 0.13
29 INT230463 Binding of MT1JP and TLR2 1 0.02 0.44 0.12
30 INT329797 Positive_regulation of TLR2 Positive_regulation of Gene_expression of IL6 1 0.02 1.67 0.11
31 INT242881 SPI1 Negative_regulation of Regulation of TLR2 1 0.04 1.13 0.11
32 INT294778 PAM Positive_regulation of Gene_expression of TLR2 1 0.01 0.41 0.11
33 INT329802 Positive_regulation of TLR2 Regulation of Gene_expression of IL6 1 0.01 1.67 0.11
34 INT294772 PAM Positive_regulation of TLR2 1 0.00 0.17 0.1
35 INT294779 IRF6 Positive_regulation of TLR2 1 0.06 0.17 0.1
36 INT175325 Binding of TLR2 and Tlr6 1 0.00 0.39 0.09
37 INT175327 Binding of TLR2 and Tlr1 1 0.00 0.39 0.09
38 INT285424 Regulation of Binding of TLR1 and TLR2 1 0.25 0.09 0.09
39 INT185383 IL10 Regulation of TLR2 1 0.06 0.68 0.04
40 INT294680 Binding of TLR2 and Tlr4 1 0.09 0.58 0.04
41 INT185378 IL1B Regulation of TLR2 1 0.04 0.68 0.04
42 INT185374 CSF2 Regulation of TLR2 1 0.04 0.68 0.04
43 INT185388 Binding of PVRL1 and TLR2 1 0.15 0.75 0.04
44 INT185382 IFNG Regulation of TLR2 1 0.09 0.69 0.04
45 INT341506 TLR2 Positive_regulation of Negative_regulation of Pdcd1 1 0.01 0.54 0.03
46 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
47 INT341486 Positive_regulation of TLR2 Positive_regulation of CD8A 1 0.11 0.3 0
48 INT283979 TLR2 Positive_regulation of Gene_expression of IL23A 1 0.09 0.96 0
49 INT341507 Positive_regulation of TLR2 Negative_regulation of Gene_expression of Pdcd1 1 0.01 0.3 0
50 INT341488 Binding of CD8A and TLR2 1 0.08 0.31 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 7097. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 7097. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
2 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
3 INT150540 Binding of TLR2 50 0.45 35.86 10.43
4 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4
5 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73
6 INT264970 Positive_regulation of Localization of TLR2 1 0.11 4.21 3.37
7 INT186805 Transcription of TLR2 12 0.63 9.66 3.04
8 INT133029 Regulation of TLR2 18 0.56 11.31 2.62
9 INT186799 Localization of TLR2 5 0.68 2.51 2.58
10 INT175307 Regulation of Gene_expression of TLR2 9 0.56 7.08 1.58
11 INT146914 Negative_regulation of TLR2 12 0.53 7.41 1.23
12 INT188575 Positive_regulation of Transcription of TLR2 1 0.30 1.37 0.88
13 INT186801 Positive_regulation of Binding of TLR2 3 0.42 2.05 0.67
14 INT290394 Negative_regulation of Positive_regulation of TLR2 4 0.34 2.8 0.65
15 INT180531 Positive_regulation of Positive_regulation of TLR2 4 0.32 4.28 0.62
16 INT325457 Negative_regulation of Binding of TLR2 1 0.04 1.3 0.43
17 INT294788 Regulation of Positive_regulation of TLR2 2 0.36 1.41 0.21
18 INT294789 Negative_regulation of Transcription of TLR2 2 0.39 0.73 0.1
19 INT341500 Regulation of Binding of TLR2 1 0.12 0.25 0
20 INT294786 Regulation of Localization of TLR2 1 0.41 0 0
21 INT294781 Negative_regulation of Negative_regulation of TLR2 1 0.39 0.08 0
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