G:718

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Official Symbol C3
Aliases ASP, AHUS5, ARMD9, CPAMD1
EntrezGene 718
UniProt Coming Soon
Unique Molecular Interactions 29
Total Molecular Interactions 43
Total Single Events 452
Unique Interaction Partners 22

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to C3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to C3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to C3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT46964 C3 Positive_regulation of Tcm 1 0.00 1.26 0.66
2 INT30129 Binding of C3 and Gast 1 0.06 0.09 0.62
3 INT149479 CEBPD Positive_regulation of C3 1 0.30 0.14 0.57
4 INT331731 Binding of C3 and CD79A 1 0.02 0.85 0.46
5 INT116358 Binding of C3 and ELANE 1 0.12 0 0.29
6 INT116356 Positive_regulation of Binding of C3 and ELANE 1 0.16 0 0.29
7 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27
8 INT24223 Ifng Negative_regulation of Gene_expression of C3 1 0.01 0 0.26
9 INT218510 Binding of C3 and Cfb 1 0.02 0.53 0.2
10 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17
11 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17
12 INT41831 Binding of ALB and C3 1 0.22 0.07 0.08
13 INT218503 Cfb Positive_regulation of C3 1 0.01 0.29 0.06
14 INT229982 Binding of C3 and amd 1 0.02 1.14 0.06
15 INT171543 IL4 Positive_regulation of Transcription of C3 1 0.28 0 0.05
16 INT171542 IL4 Positive_regulation of Gene_expression of C3 1 0.19 0 0.05
17 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05
18 INT245218 Binding of C3 and C5AR1 2 0.29 2.94 0.04
19 INT245216 Binding of C3 and C3AR1 1 0.19 1.21 0.04
20 INT281652 GOPC Positive_regulation of C3 1 0.22 0.22 0.04
21 INT279533 CFH Positive_regulation of C3 1 0.07 1.8 0
22 INT229934 Binding of C3 and GPI 1 0.01 0 0
23 INT218508 Negative_regulation of Binding of C3 and Cfb 1 0.01 0 0
24 INT279530 MBL2 Positive_regulation of Positive_regulation of C3 1 0.26 1.71 0
25 INT229930 C3AR1 Positive_regulation of C3 1 0.00 0 0
26 INT229932 C4B Positive_regulation of C3 1 0.07 0 0
27 INT345059 Binding of C3 and C2 1 0.00 0 0
28 INT279537 ICAM3 Positive_regulation of C3 1 0.06 0.85 0
29 INT299708 Binding of C3 and PSMC2 1 0.00 0.14 0
30 INT229919 GPI Negative_regulation of Binding of C3 and GPI 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 718. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 718. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT756 Gene_expression of C3 138 0.75 100.6 19.2
2 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63
3 INT573 Negative_regulation of C3 60 0.59 41.37 7.78
4 INT29094 Binding of C3 39 0.37 12.65 2.27
5 INT35689 Localization of C3 17 0.75 5.3 1.98
6 INT16385 Regulation of C3 20 0.41 9.98 1.92
7 INT46044 Positive_regulation of Gene_expression of C3 23 0.53 20.07 1.06
8 INT116360 Protein_catabolism of C3 19 0.64 4.4 1
9 INT79956 Positive_regulation of Positive_regulation of C3 4 0.35 4.17 0.86
10 INT28689 Negative_regulation of Positive_regulation of C3 4 0.23 1.28 0.85
11 INT149485 Regulation of Gene_expression of C3 5 0.60 3.39 0.75
12 INT116361 Positive_regulation of Protein_catabolism of C3 6 0.45 1.86 0.69
13 INT46173 Transcription of C3 4 0.61 3.54 0.53
14 INT46045 Negative_regulation of Gene_expression of C3 5 0.30 3.15 0.45
15 INT46174 Positive_regulation of Transcription of C3 1 0.13 0.25 0.3
16 INT79957 Regulation of Positive_regulation of C3 2 0.32 1.55 0.13
17 INT218489 Negative_regulation of Localization of C3 1 0.08 0.24 0.04
18 INT218479 Negative_regulation of Protein_catabolism of C3 1 0.09 0.24 0.04
19 INT218481 Positive_regulation of Binding of C3 2 0.35 1.23 0.03
20 INT246352 Positive_regulation of Regulation of C3 1 0.03 1.05 0.03
21 INT218480 Negative_regulation of Binding of C3 5 0.10 1.54 0
22 INT279566 Negative_regulation of Transcription of C3 1 0.30 1.49 0
23 INT218495 Negative_regulation of Negative_regulation of C3 1 0.08 0 0
24 INT218491 Phosphorylation of C3 1 0.19 0 0
25 INT218476 Regulation of Protein_catabolism of C3 1 0.06 0 0
26 INT218483 Regulation of Binding of C3 1 0.10 0 0
27 INT218475 Regulation of Phosphorylation of C3 1 0.10 0 0
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