G:7248

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Official Symbol TSC1
Aliases LAM, TSC, KIAA0243, MGC86987
EntrezGene 7248
UniProt Coming Soon
Unique Molecular Interactions 24
Total Molecular Interactions 28
Total Single Events 265
Unique Interaction Partners 20

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to TSC1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to TSC1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to TSC1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
2 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
3 INT74014 Binding of TSC1 and XRCC1 1 0.02 1.98 0.09
4 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09
5 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09
6 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08
7 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
8 INT341537 F2RL1 Positive_regulation of TSC1 1 0.01 0.76 0.03
9 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0
10 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0
11 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0
12 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0
13 INT259093 Binding of TSC1 and LMO4 1 0.02 0.74 0
14 INT217786 TSC1 Regulation of MITF 1 0.00 1.27 0
15 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
16 INT259092 TSC1 Positive_regulation of Gene_expression of TCEAL1 1 0.01 4.58 0
17 INT268596 Mir10a Regulation of TSC1 1 0.01 0.44 0
18 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0
19 INT300337 Gene_expression of MITF Negative_regulation of Gene_expression of TSC1 1 0.00 0.65 0
20 INT217784 Binding of MITF and TSC1 1 0.00 1.21 0
21 INT217774 TP53 Regulation of TSC1 1 0.02 1.28 0
22 INT217791 TP53 Positive_regulation of TSC1 1 0.04 0.61 0
23 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0
24 INT268509 MIR146B Regulation of TSC1 1 0.03 0.44 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 7248. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 7248. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
2 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
3 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
4 INT214073 Binding of TSC1 9 0.37 22 1.34
5 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
6 INT74019 Regulation of TSC1 27 0.35 23.61 0.79
7 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45
8 INT184803 Localization of TSC1 5 0.37 6.13 0.32
9 INT256540 Regulation of Gene_expression of TSC1 4 0.07 4.74 0.3
10 INT217832 Negative_regulation of Gene_expression of TSC1 5 0.04 5.45 0.21
11 INT173222 Negative_regulation of Negative_regulation of TSC1 1 0.01 0.92 0.09
12 INT190703 Regulation of Negative_regulation of TSC1 3 0.06 3.08 0.07
13 INT190057 Positive_regulation of Negative_regulation of TSC1 2 0.01 1.08 0.03
14 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03
15 INT190054 Negative_regulation of Positive_regulation of TSC1 1 0.01 0.83 0.03
16 INT175424 Regulation of Transcription of TSC1 2 0.05 1.39 0
17 INT271963 Phosphorylation of TSC1 2 0.31 2.02 0
18 INT271965 Negative_regulation of Binding of TSC1 1 0.33 0.44 0
19 INT322758 Positive_regulation of Localization of TSC1 1 0.06 1.4 0
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