G:7299

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Official Symbol TYR
Aliases CMM8, OCA1A, OCAIA, SHEP3
EntrezGene 7299
UniProt Coming Soon
Unique Molecular Interactions 14
Total Molecular Interactions 21
Total Single Events 133
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to TYR. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to TYR. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to TYR. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
2 INT102762 Binding of POMC and TYR 1 0.12 0.35 0.69
3 INT31531 Mif-ps1 Regulation of TYR 1 0.11 0 0.49
4 INT35685 TYR Regulation of Oxt 1 0.14 0.32 0.36
5 INT71640 Binding of HLA-A and TYR 1 0.16 0.36 0.27
6 INT86634 POMC Positive_regulation of TYR 2 0.42 0 0.24
7 INT131603 POMC Regulation of TYR 1 0.52 0 0.13
8 INT154736 TYR Regulation of POMC 1 0.30 0.33 0.12
9 INT55459 Binding of OPRM1 and TYR 1 0.08 0 0.1
10 INT313806 Binding of TYR and YOD1 1 0.01 0.49 0.06
11 INT313810 Binding of MET and TYR 1 0.02 0 0
12 INT313808 Binding of TYR and SPG16 1 0.01 0 0
13 INT313801 Binding of TYR and TYRP1 1 0.03 0 0
14 INT313800 Binding of HLA-B and TYR 1 0.04 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 7299. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 7299. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13010 Gene_expression of TYR 38 0.65 14.81 8.84
2 INT5481 Binding of TYR 26 0.47 1.3 7.95
3 INT49025 Positive_regulation of TYR 14 0.69 7.15 5.84
4 INT31528 Regulation of TYR 6 0.44 0.83 3.63
5 INT49020 Negative_regulation of TYR 11 0.58 1.97 2.68
6 INT71780 Phosphorylation of TYR 12 0.34 17.21 1.62
7 INT2293 Localization of TYR 3 0.61 0.16 1.06
8 INT49021 Transcription of TYR 2 0.68 0.58 0.99
9 INT148282 Positive_regulation of Gene_expression of TYR 3 0.56 0.6 0.73
10 INT49023 Regulation of Gene_expression of TYR 1 0.27 0.42 0.28
11 INT49026 Regulation of Positive_regulation of TYR 1 0.27 0.4 0.27
12 INT146028 Negative_regulation of Positive_regulation of TYR 1 0.43 0.69 0.26
13 INT212444 Positive_regulation of Phosphorylation of TYR 4 0.18 4.83 0.12
14 INT212446 Negative_regulation of Phosphorylation of TYR 1 0.11 3.4 0.04
15 INT283887 Positive_regulation of Binding of TYR 1 0.07 0.06 0
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