G:760

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Official Symbol CA2
Aliases CAII, Car2, CA-II
EntrezGene 760
UniProt Coming Soon
Unique Molecular Interactions 97
Total Molecular Interactions 115
Total Single Events 886
Unique Interaction Partners 66

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CA2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CA2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CA2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
2 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
3 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
4 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
5 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02
6 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
7 INT69506 CA2 Positive_regulation of PRKCA 1 0.50 0.42 0.98
8 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73
9 INT272147 PTAFR Positive_regulation of CA2 1 0.13 0 0.71
10 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63
11 INT275063 CA2 Positive_regulation of Positive_regulation of CAMK4 1 0.01 0 0.59
12 INT240070 KCNIP3 Regulation of CA2 1 0.02 0.72 0.59
13 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51
14 INT272148 PTAFR Regulation of Localization of CA2 1 0.14 0 0.38
15 INT235083 CA2 Positive_regulation of Gene_expression of CALM1 1 0.01 0.63 0.37
16 INT195146 Cpm Regulation of Localization of CA2 1 0.00 0.22 0.32
17 INT261047 MZB1 Positive_regulation of Positive_regulation of CA2 1 0.02 0.09 0.3
18 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27
19 INT323147 Binding of CA2 and DBT 1 0.01 0.17 0.26
20 INT130691 CA2 Positive_regulation of EIF2AK3 1 0.16 0.59 0.24
21 INT130714 CA2 Positive_regulation of Eif2s1 1 0.16 0.59 0.24
22 INT130689 CA2 Positive_regulation of ATF4 1 0.13 0.59 0.24
23 INT309751 Binding of CA2 and TRPV4 1 0.08 0 0.23
24 INT89238 Positive_regulation of RUNX1 Positive_regulation of Positive_regulation of CA2 1 0.01 0 0.22
25 INT264778 Binding of CA2 and Gabbr1 1 0.02 0 0.21
26 INT80620 CA2 Regulation of KCNIP3 1 0.11 0.08 0.21
27 INT261048 CHR Positive_regulation of CA2 1 0.03 0.21 0.21
28 INT291797 Binding of CA2 and Positive_regulation of MYLK 1 0.15 0.33 0.19
29 INT11790 CA2 Regulation of Localization of PRL 1 0.23 0 0.18
30 INT235085 NOS1 Positive_regulation of CA2 1 0.07 0.18 0.15
31 INT77121 WDTC1 Positive_regulation of Localization of CA2 1 0.10 0.39 0.15
32 INT182937 KCNIP3 Regulation of Binding of CA2 1 0.05 0.2 0.14
33 INT182958 Binding of CA2 and CREB1 1 0.04 0.25 0.13
34 INT323149 Positive_regulation of DBT Regulation of CA2 1 0.01 0 0.13
35 INT309743 Binding of CA2 and CALM3 1 0.04 0 0.13
36 INT48595 NT5C3 Positive_regulation of CA2 1 0.01 0 0.13
37 INT323151 DBT Regulation of CA2 1 0.01 0 0.13
38 INT335300 SLC15A4 Regulation of CA2 1 0.00 0.19 0.12
39 INT182951 Binding of CA2 and Positive_regulation of Localization of KCNIP3 1 0.09 0.17 0.12
40 INT350736 PRKDC Negative_regulation of CA2 1 0.02 0.16 0.11
41 INT309738 CALM3 Positive_regulation of CA2 1 0.04 0 0.08
42 INT249198 CD38 Positive_regulation of CA2 1 0.16 0.16 0.08
43 INT261049 PLA2G6 Regulation of CA2 1 0.08 0 0.08
44 INT309722 TRPV4 Positive_regulation of CA2 1 0.11 0 0.08
45 INT249162 CYBB Regulation of CA2 1 0.17 0.31 0.08
46 INT309737 Binding of CALM3 and Positive_regulation of CA2 1 0.04 0 0.08
47 INT275064 Binding of CA2 and CALM1 2 0.06 0 0.07
48 INT231635 Binding of CA2 and NUCB1 1 0.09 0.05 0.07
49 INT309723 CALM1 Regulation of CA2 1 0.01 0 0.06
50 INT309739 CA2 Negative_regulation of TRPV1 1 0.04 0 0.06
51 INT113862 Binding of CA2 and NR1H4 1 0.00 0 0.06
52 INT275103 CA2 Positive_regulation of Prkcg 1 0.01 0 0.06
53 INT309748 CALM3 Regulation of CA2 1 0.02 0 0.06
54 INT309752 CALM3 Positive_regulation of Gene_expression of CA2 1 0.04 0 0.06
55 INT350219 ITPR3 Positive_regulation of CA2 1 0.22 0 0.05
56 INT249193 Negative_regulation of CA2 Negative_regulation of Binding of AKT1 1 0.03 0.08 0.05
57 INT249160 CA2 Positive_regulation of PLA2G6 1 0.10 0 0.05
58 INT177281 Binding of CA2 and CXADR 1 0.31 0 0.04
59 INT249158 CD38 Regulation of CA2 1 0.13 0.07 0.04
60 INT309717 CALM3 Negative_regulation of Binding of CA2 and CA2 1 0.01 0 0.04
61 INT311535 ROS1 Negative_regulation of CA2 1 0.19 0.61 0.04
62 INT177275 Binding of CA2 and SV2A 1 0.30 0 0.04
63 INT249199 CA2 Positive_regulation of PLA2G4A 1 0.15 0 0.04
64 INT269596 TMPO Positive_regulation of Localization of CA2 1 0.12 0.06 0.03
65 INT317073 NA Regulation of Localization of CA2 1 0.01 0.1 0.03
66 INT317070 DNAH8 Regulation of Localization of CA2 1 0.01 0.1 0.03
67 INT249165 Binding of CA2 and Positive_regulation of CYBB 1 0.18 0 0
68 INT249200 ATP2A2 Negative_regulation of CA2 1 0.01 0 0
69 INT249178 Negative_regulation of CA2 Positive_regulation of TRPC4 1 0.16 0 0
70 INT322728 LPA Positive_regulation of CA2 1 0.04 0.09 0
71 INT308125 Binding of CA2 and F2 1 0.01 0.23 0
72 INT284143 EDN1 Positive_regulation of CA2 1 0.03 0.37 0
73 INT309719 Binding of GOPC and Positive_regulation of Binding of CA2 GOPC 1 0.01 0 0
74 INT269552 TMPO Regulation of Localization of CA2 1 0.11 0 0
75 INT179302 Gene_expression of GNAS Negative_regulation of CA2 1 0.01 0 0
76 INT249195 Binding of CA2 and S100B 1 0.07 0 0
77 INT309721 Binding of GOPC and Positive_regulation of Binding of CA2 CALM3 1 0.01 0 0
78 INT189203 CHGB Regulation of CA2 1 0.04 0.95 0
79 INT317074 CA2 Regulation of SCNN1G 1 0.01 0.08 0
80 INT75104 Binding of CA2 and PIAS1 1 0.15 0.06 0
81 INT265964 TNNI2 Regulation of CA2 1 0.22 0.09 0
82 INT189201 CHGB Regulation of Localization of CA2 1 0.04 0.95 0
83 INT309749 Binding of CA2 and GOPC 1 0.03 0 0
84 INT249167 CISH Regulation of CA2 1 0.01 0 0
85 INT249164 Negative_regulation of CA2 Positive_regulation of Gene_expression of STIM1 1 0.14 0 0
86 INT269591 MAPKAP1 Positive_regulation of CA2 1 0.04 0 0
87 INT309712 Binding of CA2 and Positive_regulation of Binding of GOPC TRPV4 1 0.03 0 0
88 INT179301 CA2 Regulation of KCNMA1 1 0.11 0 0
89 INT322729 Negative_regulation of LPA Positive_regulation of CA2 1 0.04 0.09 0
90 INT309720 Binding of CA2 and Positive_regulation of Binding of CA2 GOPC 1 0.01 0 0
91 INT249161 CA2 Regulation of CYBB 1 0.23 0 0
92 INT249172 Binding of CA2 and S100A8 1 0.14 0 0
93 INT249157 Negative_regulation of CA2 Positive_regulation of TRPC5 1 0.14 0 0
94 INT235486 S100B Positive_regulation of Binding of CA2 1 0.13 0.08 0
95 INT261040 Regulation of CHR Regulation of CA2 1 0.03 0 0
96 INT309715 Binding of CA2 and Positive_regulation of Binding of CALM3 TRPV4 1 0.04 0 0
97 INT249197 Negative_regulation of CA2 Positive_regulation of TRPC1 1 0.16 0 0
98 INT261051 CHR Regulation of CA2 1 0.03 0 0
99 INT249182 CISH Regulation of Localization of CA2 1 0.04 0 0
100 INT308121 Binding of CA2 and F10 1 0.04 0.23 0
101 INT249189 CA2 Regulation of PRKCA 1 0.04 0 0
102 INT279708 Binding of CA2 and CIB1 1 0.01 0.09 0
103 INT249190 Binding of CA2 and S100A9 1 0.13 0 0
104 INT309714 Binding of CA2 and Positive_regulation of Binding of CA2 CALM3 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 760. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 760. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97
2 INT5489 Localization of CA2 172 0.80 39.46 33.56
3 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4
4 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35
5 INT3535 Regulation of CA2 61 0.32 16.48 10.8
6 INT23535 Positive_regulation of Localization of CA2 41 0.41 13.52 9.43
7 INT195145 Positive_regulation of Gene_expression of CA2 25 0.37 7.2 6.59
8 INT5490 Binding of CA2 52 0.36 9.73 5.53
9 INT91520 Negative_regulation of Positive_regulation of CA2 7 0.30 0.99 2.92
10 INT93562 Negative_regulation of Localization of CA2 15 0.59 1.87 2.51
11 INT24283 Regulation of Positive_regulation of CA2 8 0.30 3.06 1.74
12 INT64807 Positive_regulation of Positive_regulation of CA2 10 0.41 1.21 1.7
13 INT35325 Regulation of Localization of CA2 10 0.32 1.13 1.69
14 INT23847 Phosphorylation of CA2 8 0.61 0.67 1.12
15 INT70327 Regulation of Gene_expression of CA2 11 0.28 1.92 1.05
16 INT70323 Negative_regulation of Gene_expression of CA2 13 0.41 6.55 0.97
17 INT47757 Transcription of CA2 5 0.67 1.16 0.97
18 INT264594 Negative_regulation of Binding of CA2 4 0.20 1.1 0.52
19 INT248783 Positive_regulation of Protein_catabolism of CA2 1 0.13 0 0.52
20 INT248784 Protein_catabolism of CA2 1 0.22 0 0.52
21 INT348865 Regulation of Transcription of CA2 1 0.21 0.69 0.43
22 INT47758 Positive_regulation of Transcription of CA2 3 0.49 0.54 0.42
23 INT249246 Positive_regulation of Phosphorylation of CA2 2 0.26 0.06 0.42
24 INT249273 Regulation of Regulation of CA2 3 0.23 0.26 0.31
25 INT318561 Negative_regulation of Phosphorylation of CA2 1 0.02 0 0.18
26 INT249242 Positive_regulation of Negative_regulation of CA2 1 0.26 0.34 0.09
27 INT249292 Negative_regulation of Negative_regulation of CA2 1 0.22 0 0.08
28 INT183004 Positive_regulation of Binding of CA2 1 0.10 0.07 0.04
29 INT249272 Regulation of Negative_regulation of CA2 1 0.14 0 0
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