G:81646

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Official Symbol Creb1
Aliases Creb
EntrezGene 81646
UniProt Coming Soon
Unique Molecular Interactions 114
Total Molecular Interactions 171
Total Single Events 1820
Unique Interaction Partners 62

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Creb1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Creb1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Creb1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
2 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
3 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
4 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
5 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
6 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
7 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
8 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
9 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
10 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
11 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
12 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
13 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
14 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
15 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
16 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
17 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
18 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
19 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
20 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
21 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
22 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
23 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
24 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
25 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
26 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
27 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
28 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
29 INT186448 Prkcg Regulation of Trib3 Regulation of Creb1 1 0.02 0.23 0.92
30 INT186447 Trib3 Regulation of Trib3 Regulation of Creb1 1 0.00 0.23 0.92
31 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
32 INT186446 Prkaca Regulation of Trib3 Regulation of Creb1 1 0.01 0.23 0.92
33 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
34 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
35 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
36 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
37 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
38 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
39 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
40 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
41 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
42 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
43 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
44 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
45 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
46 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
47 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
48 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
49 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
50 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
51 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
52 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
53 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
54 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
55 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
56 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
57 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
58 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
59 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
60 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
61 INT317637 Ngf Regulation of Creb1 1 0.10 0.11 0.57
62 INT73656 Creb1 Positive_regulation of Transcription of Pdyn 1 0.42 0.97 0.56
63 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56
64 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55
65 INT114921 Binding of Oprm1 and Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.06 0.05 0.54
66 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54
67 INT114930 Binding of Oprm1 and Crebbp Positive_regulation of Positive_regulation of Creb1 1 0.06 0 0.51
68 INT114931 Binding of Oprm1 and Creb1 Positive_regulation of Positive_regulation of Creb1 1 0.16 0 0.51
69 INT309168 Pik3cb Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.01 0.37 0.5
70 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
71 INT309169 Ephb1 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.01 0.37 0.48
72 INT309167 Akt1 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.01 0.37 0.48
73 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
74 INT317640 Slc3a1 Positive_regulation of Creb1 1 0.12 0.58 0.46
75 INT161162 Creb1 Regulation of Nts 1 0.19 0.15 0.45
76 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
77 INT317636 Creb1 Positive_regulation of Phosphorylation of Hmmr 1 0.04 0.55 0.45
78 INT283731 Trib3 Positive_regulation of Creb1 2 0.01 0.16 0.44
79 INT309113 Edc4 Positive_regulation of Gene_expression of Creb1 1 0.03 0.45 0.43
80 INT106333 Olr1254 Positive_regulation of Creb1 1 0.02 0 0.43
81 INT106337 Olr1254 Positive_regulation of Olr1254 Positive_regulation of Creb1 1 0.00 0 0.43
82 INT309145 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.02 0.35 0.42
83 INT340607 Bdnf Regulation of Gene_expression of Creb1 1 0.36 0.31 0.36
84 INT126851 Prkcg Positive_regulation of Creb1 1 0.46 0.09 0.32
85 INT126852 Prkaca Positive_regulation of Creb1 1 0.27 0.09 0.32
86 INT186430 Creb1 Positive_regulation of Trib3 1 0.04 0.17 0.3
87 INT118655 Bdnf Positive_regulation of Phosphorylation of Creb1 1 0.44 0.16 0.3
88 INT118653 Binding of Bdnf and Creb1 1 0.39 0.19 0.3
89 INT73657 Binding of Jun and Creb1 1 0.25 0.5 0.29
90 INT179425 Fig4 Regulation of Creb1 1 0.02 0.32 0.28
91 INT283732 Prkaca Positive_regulation of Creb1 1 0.03 0 0.28
92 INT51858 Akr1d1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0 0.27
93 INT95741 Creb1 Regulation of Mapk8 1 0.39 0 0.23
94 INT150582 Creb1 Positive_regulation of Gene_expression of Homer1 1 0.00 0 0.22
95 INT87169 Creb1 Positive_regulation of Gene_expression of Nkx1-1 1 0.11 0.17 0.21
96 INT137228 MAPK1 Positive_regulation of Phosphorylation of Creb1 1 0.46 0 0.2
97 INT99797 Jun Positive_regulation of Creb1 1 0.15 0.19 0.2
98 INT320260 Binding of Atf4 and Creb1 1 0.15 0.36 0.17
99 INT114936 Myoz1 Positive_regulation of Creb1 1 0.00 0 0.17
100 INT320257 Binding of Atf3 and Creb1 1 0.15 0.36 0.17
101 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
102 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
103 INT309130 Edc4 Regulation of Creb1 1 0.02 0.12 0.13
104 INT266063 PAG1 Regulation of Gene_expression of Creb1 1 0.06 0.53 0.12
105 INT286046 Binding of Wwox and Creb1 1 0.14 1.67 0.1
106 INT171163 Creb1 Regulation of Sp1 1 0.03 0.62 0.1
107 INT261892 Creb1 Regulation of Gene_expression of Ppp1r1b 1 0.31 1.46 0.09
108 INT114932 Slc12a6 Positive_regulation of Phosphorylation of Creb1 1 0.00 0 0.08
109 INT249466 Slc6a4 Positive_regulation of Phosphorylation of Creb1 1 0.09 0.36 0.07
110 INT77722 Ptger2 Positive_regulation of Phosphorylation of Creb1 1 0.13 0 0.07
111 INT254462 Binding of Ca2 and Creb1 1 0.16 0 0.07
112 INT303062 Rorb Regulation of Creb1 1 0.00 1.06 0.06
113 INT92567 Creb1 Positive_regulation of Binding of Prkaca 1 0.06 0 0.05
114 INT309137 Edc4 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.04
115 INT309111 Dlat Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.04
116 INT307450 Bdnf Positive_regulation of Transcription of Creb1 1 0.07 0.25 0.04
117 INT50695 Crem Positive_regulation of Phosphorylation of Creb1 1 0.07 0 0
118 INT286728 Creb1 Regulation of Ppargc1a 1 0.29 0 0
119 INT267018 Bdnf Positive_regulation of Gene_expression of Creb1 1 0.10 0 0
120 INT74028 Creb1 Positive_regulation of Penk 1 0.43 0.07 0
121 INT163238 Creb1 Positive_regulation of Positive_regulation of Ltp 1 0.09 0.06 0
122 INT74025 Creb1 Regulation of Transcription of Penk 1 0.57 0 0
123 INT286030 Creb1 Regulation of Transcription of Bcl2 1 0.07 0.34 0
124 INT50693 Binding of Penk and Creb1 1 0.49 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 81646. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 81646. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
2 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
3 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
4 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
5 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
6 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
7 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
8 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
9 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
10 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
11 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
12 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
13 INT16713 Binding of Creb1 53 0.48 20.24 13.06
14 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
15 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
16 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
17 INT61986 Localization of Creb1 16 0.69 2.12 5.66
18 INT111554 Positive_regulation of Regulation of Creb1 4 0.50 2.12 2.85
19 INT156021 Positive_regulation of Transcription of Creb1 8 0.57 3.36 2.83
20 INT87168 Positive_regulation of Binding of Creb1 4 0.48 4.6 2.21
21 INT98923 Negative_regulation of Localization of Creb1 3 0.50 0.66 1.26
22 INT71476 Negative_regulation of Regulation of Creb1 1 0.18 0.17 1.06
23 INT93674 Regulation of Binding of Creb1 1 0.38 0.1 0.62
24 INT317620 Negative_regulation of Binding of Creb1 1 0.40 0.81 0.46
25 INT266053 Positive_regulation of Protein_catabolism of Creb1 1 0.50 0.96 0.17
26 INT266056 Protein_catabolism of Creb1 1 0.88 0.95 0.16
27 INT338872 Regulation of Regulation of Creb1 1 0.21 0.28 0.15
28 INT266058 Regulation of Localization of Creb1 1 0.39 0.38 0.11
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