G:81648

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Official Symbol Crh
Aliases CRF
EntrezGene 81648
UniProt Coming Soon
Unique Molecular Interactions 168
Total Molecular Interactions 307
Total Single Events 2287
Unique Interaction Partners 72

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Crh. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Crh. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Crh. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
2 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
3 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
4 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
5 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
6 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
7 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
8 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
9 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
10 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
11 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
12 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
13 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
14 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
15 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
16 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
17 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
18 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
19 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
20 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
21 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
22 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
23 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
24 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
25 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
26 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
27 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
28 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
29 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
30 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
31 INT29713 Crh Negative_regulation of Localization of Gnrhr 1 0.39 0 1.12
32 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
33 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
34 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
35 INT5612 Cck Positive_regulation of Localization of Crh 1 0.65 0.16 1
36 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99
37 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
38 INT36002 Negative_regulation of Crh Negative_regulation of LH 2 0.29 0.66 0.96
39 INT62449 Gnrh1 Regulation of Crh 1 0.40 0.34 0.91
40 INT66371 Pomc Regulation of Gene_expression of Crh 2 0.49 0 0.88
41 INT21006 Oprl1 Regulation of Localization of Crh 1 0.19 0 0.84
42 INT64629 Binding of Gal and Crh 1 0.18 0.1 0.83
43 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
44 INT36003 Crh Positive_regulation of Localization of LH 2 0.45 0 0.79
45 INT79532 Crh Regulation of Ugt1a10 1 0.00 0 0.76
46 INT28620 Penk Regulation of Crh 2 0.40 0.25 0.75
47 INT30838 Crh Negative_regulation of D230030E09Rik 1 0.17 0.1 0.73
48 INT5971 Il1a Positive_regulation of Crh 2 0.51 0.57 0.71
49 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 0.05 0.66 0.71
50 INT12022 Crh Positive_regulation of Localization of Prl 1 0.02 0.14 0.7
51 INT26198 Positive_regulation of Crh Positive_regulation of Localization of POMC 1 0.38 0 0.7
52 INT55205 Prl Positive_regulation of Localization of Crh 1 0.47 0 0.69
53 INT55209 Prl Positive_regulation of Crh 1 0.51 0 0.69
54 INT253825 Cck Positive_regulation of Crh 1 0.74 0 0.69
55 INT135119 Binding of Pomc and Crh 1 0.35 0 0.67
56 INT103905 Gh Positive_regulation of Positive_regulation of Crh 1 0.08 0.9 0.66
57 INT97508 Negative_regulation of Il1b Positive_regulation of Crh 1 0.31 0.89 0.65
58 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64
59 INT34212 PSG2 Regulation of Localization of Crh 1 0.02 0.09 0.63
60 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
61 INT23576 Binding of Penk and Crh 2 0.18 0 0.62
62 INT20162 Crh Regulation of GNRH1 2 0.02 0.07 0.62
63 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61
64 INT91391 Crh Regulation of Localization of Gnrh1 2 0.36 1.78 0.61
65 INT62461 Pomc Regulation of Il2 Positive_regulation of Crh 1 0.12 0.13 0.6
66 INT57246 Crh Positive_regulation of Positive_regulation of Caprin2 1 0.01 0.55 0.6
67 INT104050 Binding of Crh and Nts 1 0.40 0 0.6
68 INT59540 Crh Regulation of Gnrh1 2 0.36 2.61 0.58
69 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58
70 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58
71 INT62445 Pomc Negative_regulation of Localization of Crh 1 0.12 0.07 0.58
72 INT30268 Binding of Gnrh1 and Crh 1 0.45 0.65 0.57
73 INT77367 IFNA1 Positive_regulation of Positive_regulation of Crh 1 0.05 0.76 0.57
74 INT30267 Binding of Crh and Gnrhr 1 0.33 0.65 0.57
75 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
76 INT141020 Crh Positive_regulation of Gene_expression of Pomc 1 0.05 0.17 0.55
77 INT87557 Crh Positive_regulation of Prkaca 1 0.27 0 0.52
78 INT55208 Prl Negative_regulation of Localization of Crh 1 0.43 0 0.51
79 INT127337 Crh Regulation of LOC308670 1 0.01 0 0.51
80 INT62446 Il6 Positive_regulation of Crh 1 0.22 0.05 0.5
81 INT27066 Crh Positive_regulation of Localization of Oxt 1 0.40 0 0.48
82 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47
83 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47
84 INT28619 Negative_regulation of Penk Regulation of Crh 1 0.41 0 0.46
85 INT62447 Gnrh1 Regulation of Localization of Crh 1 0.40 0.17 0.45
86 INT57983 Il1b Regulation of Crh 1 0.37 0.09 0.44
87 INT57981 Regulation of Il1b Positive_regulation of Crh 1 0.22 0.1 0.44
88 INT30083 Binding of Crh and Lvp1 1 0.00 0.35 0.44
89 INT139486 Oprm1 Positive_regulation of Crh 1 0.27 0.1 0.42
90 INT55202 Crh Positive_regulation of Negative_regulation of Prl 1 0.51 0 0.41
91 INT91107 Positive_regulation of Ptgs1 Positive_regulation of Localization of Crh 1 0.00 0.56 0.41
92 INT59541 Crh Positive_regulation of Crh Regulation of Gnrh1 1 0.26 0.55 0.4
93 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38
94 INT41460 Crh Regulation of Pomc 1 0.10 0.1 0.36
95 INT26197 Qrfp Regulation of Localization of Crh 1 0.02 0 0.36
96 INT41461 Crh Regulation of Localization of Pomc 1 0.10 0.1 0.36
97 INT66368 Pomc Regulation of Positive_regulation of Crh 1 0.36 0 0.35
98 INT37552 Crh Regulation of Avp 1 0.22 0 0.34
99 INT37551 Positive_regulation of Crh Regulation of Avp 1 0.38 0 0.34
100 INT37553 Crh Regulation of FDX1 1 0.03 0 0.34
101 INT30418 Crh Negative_regulation of Localization of Gh1 1 0.41 0.72 0.33
102 INT30524 Crh Regulation of Oprl1 1 0.15 0.15 0.33
103 INT82904 Crh Negative_regulation of ge 1 0.00 1.3 0.33
104 INT26196 Npy Positive_regulation of Localization of Crh 1 0.40 0 0.33
105 INT26071 Adarb1 Regulation of Localization of Crh 1 0.01 0.21 0.32
106 INT30420 Crh Positive_regulation of Localization of Gh1 1 0.67 0.47 0.32
107 INT107944 Crh Regulation of Adarb1 1 0.06 0 0.32
108 INT141019 Crh Positive_regulation of Gene_expression of Pomc 1 0.20 0.1 0.31
109 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29
110 INT74331 Crh Regulation of Transcription of Penk 1 0.40 0.25 0.29
111 INT74335 Penk Regulation of Transcription of Crh 1 0.40 0.25 0.29
112 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
113 INT74330 Crh Regulation of Transcription of Fos 1 0.49 0.24 0.28
114 INT56978 Crh Positive_regulation of Localization of Gnrh1 1 0.10 0 0.24
115 INT154523 Binding of Oxt and Crh 1 0.11 0 0.24
116 INT177477 Crh Positive_regulation of Crh Regulation of POMC 1 0.02 0.86 0.22
117 INT92205 Crh Positive_regulation of Localization of SST 1 0.30 0.87 0.21
118 INT177479 Negative_regulation of Crh Regulation of POMC 1 0.05 0.84 0.21
119 INT33560 Binding of POMC and Crh 1 0.24 0.22 0.2
120 INT62451 Il2 Regulation of Localization of Crh 1 0.53 0.19 0.2
121 INT25053 Crh Regulation of PLOD1 1 0.11 0 0.19
122 INT25052 Crh Regulation of FSHR 1 0.08 0 0.19
123 INT59589 Npy Regulation of Crh 1 0.27 0 0.18
124 INT55988 POMC Positive_regulation of Negative_regulation of Crh 1 0.01 0 0.18
125 INT342647 Negative_regulation of Binding of Avp and Crh 1 0.37 0.64 0.18
126 INT59588 Npy Positive_regulation of Crh 1 0.41 0 0.18
127 INT59587 Npy Regulation of Gene_expression of Crh 1 0.27 0 0.18
128 INT33694 Crh Negative_regulation of Rhd 1 0.08 1.41 0.18
129 INT124236 Crh Regulation of Localization of BTF3 1 0.00 0.32 0.18
130 INT34351 Crh Regulation of DBI 1 0.00 0.25 0.17
131 INT222505 Gene_expression of Crh Negative_regulation of Gene_expression of Hpse 1 0.02 0.55 0.17
132 INT25050 Crh Negative_regulation of PLOD1 1 0.11 0 0.17
133 INT25054 Crh Negative_regulation of FSHR 1 0.07 0 0.17
134 INT17922 Positive_regulation of Crh Positive_regulation of Fos 1 0.23 0.19 0.17
135 INT5520 Negative_regulation of Dbi Negative_regulation of Gene_expression of Crh 1 0.21 0.44 0.16
136 INT5521 Oprd1 Negative_regulation of Gene_expression of Crh 1 0.11 0.43 0.16
137 INT5517 Negative_regulation of Dbi Negative_regulation of Crh 1 0.27 0.44 0.16
138 INT5522 Pomc Negative_regulation of Gene_expression of Crh 1 0.27 0.39 0.16
139 INT5516 Oprd1 Negative_regulation of Crh 1 0.15 0.43 0.16
140 INT30084 Lvp1 Regulation of Localization of Crh 1 0.00 0.14 0.16
141 INT30421 Gnrhr Regulation of Crh 1 0.11 0.27 0.15
142 INT39154 Crh Positive_regulation of Avp 2 0.11 0.15 0.14
143 INT177480 Positive_regulation of Crh Positive_regulation of Regulation of POMC 1 0.06 0.46 0.14
144 INT293119 Agtr1a Regulation of Positive_regulation of Crh 1 0.12 0.37 0.14
145 INT293115 Agt Regulation of Positive_regulation of Crh 1 0.16 0.37 0.14
146 INT33749 Crh Positive_regulation of Localization of Agt 1 0.31 0 0.13
147 INT8162 Fos Regulation of Gene_expression of Crh 1 0.35 0.31 0.13
148 INT62748 Crh Regulation of Gal 1 0.27 0.36 0.12
149 INT168578 Crh Positive_regulation of Hrasls 1 0.06 0 0.12
150 INT5519 Dbi Negative_regulation of Crh 1 0.31 0.28 0.1
151 INT186539 Crh Regulation of Hpse 1 0.09 0.52 0.1
152 INT124235 Crh Regulation of BTF3 1 0.00 0.16 0.09
153 INT75372 ecs Positive_regulation of Gene_expression of Crh 1 0.03 0.62 0.09
154 INT81424 Binding of Crh and Olr1000 1 0.06 0.17 0.09
155 INT25950 Ins1 Regulation of Crh 1 0.14 0.07 0.09
156 INT33471 POMC Positive_regulation of Localization of Crh 1 0.11 0 0.08
157 INT94353 Crh Negative_regulation of Positive_regulation of Dbi 1 0.03 0.14 0.08
158 INT94354 Crh Negative_regulation of Dbi 1 0.03 0.14 0.08
159 INT32745 Crh Positive_regulation of Localization of Pomc 2 0.16 0.49 0.07
160 INT25296 Oxt Regulation of Localization of Crh 1 0.01 0.18 0.07
161 INT53857 Negative_regulation of Crh Positive_regulation of GNRH1 1 0.13 0.5 0.07
162 INT75373 ecs Regulation of Gene_expression of Crh 1 0.01 1.18 0.06
163 INT29385 Positive_regulation of Crh Regulation of Pomc 1 0.00 0.21 0.06
164 INT37493 Crh Negative_regulation of Gnrh1 1 0.36 0 0.05
165 INT222544 Binding of Ucn and Crh 1 0.02 0 0.05
166 INT222565 Crh Positive_regulation of Transcription of Pomc 1 0.10 0.35 0.03
167 INT33690 Crh Regulation of Regulation of Gnrh1 1 0.31 0.95 0.03
168 INT25051 Crh Negative_regulation of Localization of FSHR 1 0.07 0 0
169 INT25049 Crh Negative_regulation of Localization of PLOD1 1 0.10 0 0
170 INT222413 Nps Positive_regulation of Localization of Crh 1 0.03 0.66 0
171 INT33693 Crh Regulation of Regulation of Rhd 1 0.06 0.86 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 81648. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 81648. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1562 Localization of Crh 499 0.81 126.74 236.68
2 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
3 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
4 INT1898 Regulation of Crh 220 0.62 61.33 102.64
5 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
6 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
7 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
8 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
9 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
10 INT16879 Binding of Crh 72 0.48 21.65 28.43
11 INT21379 Transcription of Crh 65 0.72 15.64 27.92
12 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
13 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
14 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
15 INT22336 Positive_regulation of Transcription of Crh 18 0.68 4.61 6.91
16 INT22485 Negative_regulation of Positive_regulation of Crh 13 0.59 4.49 5.46
17 INT18244 Regulation of Positive_regulation of Crh 11 0.45 3.87 5.41
18 INT22338 Negative_regulation of Transcription of Crh 11 0.43 2.09 5.24
19 INT63441 Regulation of Transcription of Crh 9 0.60 4.51 3.9
20 INT28715 Negative_regulation of Regulation of Crh 7 0.43 0.97 3.06
21 INT5510 Negative_regulation of Negative_regulation of Crh 8 0.43 1.05 2.61
22 INT22339 Positive_regulation of Negative_regulation of Crh 5 0.67 1.36 2.59
23 INT30834 Regulation of Negative_regulation of Crh 3 0.45 0.62 1.81
24 INT18710 Regulation of Regulation of Crh 6 0.60 0.79 1.6
25 INT25043 Positive_regulation of Regulation of Crh 5 0.50 1 1.06
26 INT58050 Regulation of Binding of Crh 2 0.42 0.84 0.86
27 INT83897 Protein_catabolism of Crh 2 0.86 1.75 0.39
28 INT55986 Positive_regulation of Binding of Crh 1 0.48 0.76 0.19
29 INT92090 Negative_regulation of Protein_catabolism of Crh 1 0.04 0.99 0.12
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