G:81649

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Official Symbol Mapk14
Aliases RK, Hog, p38, CRK1, CSBP, Exip, Mxi2, CSPB1, Csbp1, Csbp2, Prkm14, Prkm15, Sapk2A, p38Hog, p38alpha, MGC105413
EntrezGene 81649
UniProt Coming Soon
Unique Molecular Interactions 74
Total Molecular Interactions 83
Total Single Events 1203
Unique Interaction Partners 47

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Mapk14. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Mapk14. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Mapk14. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
2 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
3 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
4 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
5 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
6 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
7 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
8 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
9 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09
10 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
11 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
12 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
13 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
14 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95
15 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
16 INT318461 Nnat Positive_regulation of Mapk14 1 0.05 0.97 0.92
17 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
18 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
19 INT128590 Mapk14 Regulation of Nav1 1 0.21 0.25 0.82
20 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
21 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
22 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
23 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
24 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
25 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68
26 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
27 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
28 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
29 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
30 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63
31 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
32 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
33 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61
34 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59
35 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55
36 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55
37 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
38 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54
39 INT313376 Cnr1 Positive_regulation of Phosphorylation of Mapk14 1 0.20 0.38 0.5
40 INT104960 Ephb1 Regulation of Positive_regulation of Mapk14 1 0.15 0.42 0.5
41 INT313375 Cnr2 Positive_regulation of Phosphorylation of Mapk14 1 0.18 0.39 0.5
42 INT104961 Mapk14 Regulation of Positive_regulation of Ephb1 1 0.15 0.42 0.5
43 INT131504 Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.14 0.2 0.47
44 INT131507 Ngf Positive_regulation of Mapk14 1 0.13 0.2 0.47
45 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
46 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44
47 INT264479 Il1a Positive_regulation of Gene_expression of Mapk14 1 0.02 0 0.43
48 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42
49 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
50 INT95402 Mapk14 Regulation of Positive_regulation of Trib3 1 0.06 0.19 0.41
51 INT264482 Il1a Positive_regulation of Phosphorylation of Mapk14 1 0.02 0 0.37
52 INT264481 Il1a Positive_regulation of Mapk14 1 0.02 0 0.37
53 INT167982 Mapk14 Negative_regulation of gr 1 0.02 0.45 0.29
54 INT196584 Binding of Mapk14 and NeuN 1 0.02 0.39 0.27
55 INT270216 Mapk14 Positive_regulation of Mknk1 1 0.10 0.5 0.26
56 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25
57 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24
58 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17
59 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11
60 INT300306 Agt Positive_regulation of Mapk14 1 0.14 1.51 0.11
61 INT218662 Olr811 Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.54 0.08
62 INT268925 Igfbp2 Negative_regulation of Phosphorylation of Mapk14 1 0.01 0.35 0.08
63 INT300304 Positive_regulation of Mapk14 Positive_regulation of Agt 1 0.14 1.5 0.08
64 INT300308 Positive_regulation of Mapk14 Positive_regulation of Trib3 1 0.03 1.42 0.07
65 INT243670 Mp Regulation of Positive_regulation of Mapk14 1 0.00 0.06 0.06
66 INT218704 Mapk14 Regulation of EPHB2 1 0.01 0.33 0.05
67 INT218666 Olr811 Regulation of Mapk14 1 0.00 0.33 0.05
68 INT218676 Mapk8 Regulation of Mapk14 1 0.00 0.33 0.05
69 INT200889 Acsl1 Positive_regulation of Mapk14 1 0.01 0.09 0.05
70 INT295294 Tlr4 Positive_regulation of Mapk14 1 0.00 0.39 0.05
71 INT352460 Gse1 Negative_regulation of Gene_expression of Mapk14 1 0.02 0.05 0.03
72 INT295291 Mapk14 Positive_regulation of Gene_expression of Nos2 1 0.04 0.05 0
73 INT216284 Bdnf Negative_regulation of Phosphorylation of Mapk14 1 0.04 0.97 0
74 INT295293 Kcnn3 Regulation of Positive_regulation of Mapk14 1 0.11 0.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 81649. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 81649. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
2 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
3 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
4 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
5 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
6 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
7 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
8 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
9 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31
10 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63
11 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81
12 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14
13 INT128587 Localization of Mapk14 15 0.81 8.41 6.1
14 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03
15 INT171472 Binding of Mapk14 10 0.36 6.79 4.83
16 INT131782 Regulation of Positive_regulation of Mapk14 7 0.43 2.68 4.02
17 INT155453 Protein_catabolism of Mapk14 6 0.36 4.24 2.85
18 INT96901 Regulation of Negative_regulation of Mapk14 3 0.45 4.07 2.79
19 INT118907 Negative_regulation of Negative_regulation of Mapk14 2 0.57 2.09 1.77
20 INT168686 Transcription of Mapk14 6 0.52 2.96 1.67
21 INT145028 Positive_regulation of Localization of Mapk14 2 0.20 0.85 0.96
22 INT301057 Regulation of Transcription of Mapk14 1 0.25 0.5 0.29
23 INT345923 Positive_regulation of Transcription of Mapk14 1 0.07 0.41 0.25
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