G:836

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Official Symbol CASP3
Aliases CPP32, SCA-1, CPP32B
EntrezGene 836
UniProt Coming Soon
Unique Molecular Interactions 28
Total Molecular Interactions 30
Total Single Events 606
Unique Interaction Partners 23

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CASP3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CASP3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CASP3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66
2 INT11558 POMC Positive_regulation of CASP3 1 0.05 0 0.62
3 INT234609 Binding of CASP3 and IMMT 1 0.00 0.5 0.5
4 INT121249 Binding of ANXA5 and CASP3 1 0.36 0.67 0.25
5 INT121248 MEFV Positive_regulation of Binding of ANXA5 and CASP3 1 0.45 0.67 0.25
6 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24
7 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
8 INT175966 Kctd1 Negative_regulation of Positive_regulation of CASP3 1 0.09 0.82 0.06
9 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
10 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06
11 INT344254 Binding of PARP1 and CASP3 1 0.06 0.94 0.06
12 INT302162 CASP8 Positive_regulation of CASP3 2 0.01 2.07 0.04
13 INT234379 BAX Positive_regulation of CASP3 1 0.04 1.16 0.04
14 INT193778 ITIH4 Positive_regulation of CASP3 1 0.03 0.98 0.03
15 INT175946 RSF1 Positive_regulation of Positive_regulation of CASP3 1 0.01 0.41 0.03
16 INT327981 CASP9 Positive_regulation of CASP3 2 0.29 1.34 0
17 INT348532 TP63 Positive_regulation of CASP3 1 0.04 0.55 0
18 INT279798 APAF1 Positive_regulation of CASP3 1 0.01 1 0
19 INT349220 Binding of CASP3 and CD8A 1 0.00 0.18 0
20 INT186096 EGF Regulation of Positive_regulation of CASP3 1 0.01 0.28 0
21 INT327982 PNLIP Regulation of Gene_expression of CASP3 1 0.13 0.58 0
22 INT167401 Ros1 Positive_regulation of CASP3 1 0.15 0.71 0
23 INT336036 Positive_regulation of CASP9 Positive_regulation of CASP3 1 0.05 0.75 0
24 INT265460 CSPG4 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.27 0
25 INT247888 Narfl Positive_regulation of CASP3 1 0.00 0.77 0
26 INT327979 Positive_regulation of CASP9 Positive_regulation of Gene_expression of CASP3 1 0.07 0.78 0
27 INT348535 CASP10 Positive_regulation of CASP3 1 0.03 0.3 0
28 INT247889 Positive_regulation of Narfl Positive_regulation of CASP3 1 0.00 0.84 0
29 INT122482 Negative_regulation of CASP3 Negative_regulation of Positive_regulation of CASP8 1 0.14 1.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 836. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 836. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
2 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
3 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
4 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
5 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45
6 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95
7 INT88805 Protein_catabolism of CASP3 24 0.86 18.38 3.7
8 INT97126 Regulation of CASP3 9 0.40 8.15 3.6
9 INT108589 Negative_regulation of Gene_expression of CASP3 13 0.57 10.52 2.14
10 INT102845 Localization of CASP3 7 0.81 2.81 1.06
11 INT131976 Positive_regulation of Protein_catabolism of CASP3 4 0.49 3.76 0.64
12 INT132496 Regulation of Gene_expression of CASP3 6 0.20 4.59 0.42
13 INT159320 Negative_regulation of Protein_catabolism of CASP3 1 0.21 0.59 0.27
14 INT178607 Binding of CASP3 5 0.19 1.06 0.16
15 INT190821 Positive_regulation of Negative_regulation of CASP3 1 0.06 0.51 0.1
16 INT265483 Phosphorylation of CASP3 1 0.22 0.25 0.04
17 INT243797 Transcription of CASP3 2 0.09 0.82 0
18 INT348502 Regulation of Negative_regulation of CASP3 1 0.09 0.38 0
19 INT208466 Positive_regulation of Localization of CASP3 1 0.01 0.98 0
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