G:842

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Official Symbol CASP9
Aliases MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, CASPASE-9c
EntrezGene 842
UniProt Coming Soon
Unique Molecular Interactions 24
Total Molecular Interactions 26
Total Single Events 179
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CASP9. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CASP9. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CASP9. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130921 HMHA1 Positive_regulation of CASP9 1 0.03 1.37 0.14
2 INT130919 HMHA1 Positive_regulation of Protein_catabolism of CASP9 1 0.03 1.37 0.14
3 INT193697 Apaf1 Positive_regulation of CASP9 1 0.02 1.84 0.12
4 INT302161 AKT1 Negative_regulation of CASP9 1 0.03 0.87 0.11
5 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
6 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
7 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
8 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
9 INT265462 CSPG4 Negative_regulation of Positive_regulation of CASP9 1 0.07 1.2 0.04
10 INT265461 CSPG4 Negative_regulation of Gene_expression of CASP9 1 0.06 1.2 0.04
11 INT201770 Binding of CASP9 and Apaf1 1 0.04 0.89 0.03
12 INT327981 CASP9 Positive_regulation of CASP3 2 0.29 1.34 0
13 INT322559 TNFSF10 Positive_regulation of CASP9 1 0.03 1.79 0
14 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0
15 INT327978 PNLIP Regulation of Regulation of CASP9 1 0.19 0.57 0
16 INT322561 Negative_regulation of TNFSF10 Positive_regulation of CASP9 1 0.03 1.15 0
17 INT348530 CASP10 Positive_regulation of CASP9 1 0.02 0.3 0
18 INT336036 Positive_regulation of CASP9 Positive_regulation of CASP3 1 0.05 0.75 0
19 INT336037 CASP8 Positive_regulation of Positive_regulation of CASP9 1 0.01 0.59 0
20 INT348536 Positive_regulation of TP63 Positive_regulation of Gene_expression of CASP9 1 0.02 0.55 0
21 INT201769 Akt1 Negative_regulation of Phosphorylation of CASP9 1 0.00 0.82 0
22 INT327979 Positive_regulation of CASP9 Positive_regulation of Gene_expression of CASP3 1 0.07 0.78 0
23 INT318223 BAX Regulation of CASP9 1 0.09 0.18 0
24 INT200646 AKT1 Regulation of CASP9 1 0.10 1.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 842. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 842. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95120 Positive_regulation of CASP9 76 0.67 67.55 5.33
2 INT151467 Localization of CASP9 9 0.73 7.62 2.04
3 INT122488 Protein_catabolism of CASP9 8 0.46 8.64 1.8
4 INT122487 Positive_regulation of Positive_regulation of CASP9 16 0.67 17.88 1.79
5 INT122485 Negative_regulation of CASP9 18 0.46 15.78 1.12
6 INT151466 Binding of CASP9 3 0.36 2.44 0.5
7 INT292751 Negative_regulation of Localization of CASP9 1 0.41 2.11 0.22
8 INT125101 Gene_expression of CASP9 24 0.35 16.54 0.17
9 INT125103 Positive_regulation of Gene_expression of CASP9 5 0.31 2.52 0.06
10 INT265496 Positive_regulation of Localization of CASP9 2 0.25 1.89 0.05
11 INT265492 Negative_regulation of Positive_regulation of CASP9 4 0.57 3.61 0
12 INT318238 Regulation of CASP9 2 0.25 1.29 0
13 INT200680 Phosphorylation of CASP9 2 0.25 1.33 0
14 INT300640 Transcription of CASP9 1 0.23 1.11 0
15 INT322583 Positive_regulation of Protein_catabolism of CASP9 1 0.06 1.14 0
16 INT318229 Regulation of Gene_expression of CASP9 1 0.13 0.18 0
17 INT200674 Regulation of Positive_regulation of CASP9 1 0.09 1.24 0
18 INT122484 Negative_regulation of Negative_regulation of CASP9 1 0.34 1.03 0
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