G:8654

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Official Symbol PDE5A
Aliases CN5A, PDE5, CGB-PDE
EntrezGene 8654
UniProt Coming Soon
Unique Molecular Interactions 4
Total Molecular Interactions 4
Total Single Events 328
Unique Interaction Partners 3

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PDE5A. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PDE5A. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PDE5A. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT263180 Binding of PDE5A and COPD 1 0.01 1 0.15
2 INT263175 PDE5A Regulation of COPD 1 0.00 1 0.15
3 INT331897 Binding of PDE5A and Pde5a 1 0.02 0.64 0.03
4 INT209159 Binding of LHCGR and PDE5A 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 8654. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 8654. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09
2 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7
3 INT242945 Localization of PDE5A 9 0.75 4.57 1.28
4 INT79598 Regulation of PDE5A 16 0.60 8.68 1.17
5 INT103043 Binding of PDE5A 16 0.37 7.79 1.12
6 INT242944 Negative_regulation of Localization of PDE5A 3 0.35 3.18 0.59
7 INT130371 Negative_regulation of Gene_expression of PDE5A 3 0.43 1.59 0.45
8 INT79597 Positive_regulation of Negative_regulation of PDE5A 5 0.50 3.39 0.41
9 INT130372 Transcription of PDE5A 7 0.72 1.93 0.4
10 INT79599 Protein_catabolism of PDE5A 7 1.00 3.16 0.39
11 INT117995 Regulation of Negative_regulation of PDE5A 3 0.44 2.4 0.29
12 INT303483 Positive_regulation of PDE5A 2 0.39 1.5 0.23
13 INT213222 Negative_regulation of Protein_catabolism of PDE5A 1 0.24 0.65 0.16
14 INT263121 Negative_regulation of Negative_regulation of PDE5A 2 0.43 1.33 0.14
15 INT242949 Phosphorylation of PDE5A 2 0.68 0.05 0.13
16 INT303482 Positive_regulation of Protein_catabolism of PDE5A 1 0.20 1.27 0.1
17 INT213216 Positive_regulation of Gene_expression of PDE5A 2 0.37 2.08 0.04
18 INT269744 Negative_regulation of Binding of PDE5A 2 0.43 0.74 0
19 INT162907 Regulation of Gene_expression of PDE5A 2 0.51 0 0
20 INT269741 Positive_regulation of Localization of PDE5A 1 0.04 0.65 0
21 INT162922 Negative_regulation of Transcription of PDE5A 1 0.41 0 0
22 INT92876 Regulation of Protein_catabolism of PDE5A 1 0.45 0.71 0
23 INT162912 Regulation of Transcription of PDE5A 1 0.44 0 0
24 INT162915 Positive_regulation of Regulation of PDE5A 1 0.40 0 0
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